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Background: Neuroinflammation may be associated with global vascular dysfunction and damage. APOE-ε4, a major genetic risk factor for late onset AD, is expressed in neuroinflammatory cells and may lead to increased pro-inflammatory cytokine and nitric oxide production in response to injury. We examined the relationship of vascular dysfunction and damage with a magnetic resonance spectroscopy (MRS)
Accurate monitoring of glaciers’ extents and their dynamics is essential for improving our understanding of the impacts of climate and environmental changes in cold regions. The satellite-based Normalized Difference Snow Index (NDSI) has been widely used for mapping snow cover and glaciers around the globe. However, mapping glaciers in snow-covered areas using existing indices remains a challengin
The urgency of addressing the sustainability crisis requires a comprehensive approach encompassing both technological advancements and changes in human behavior. Food represents a crucial domain where everyday choices closely intertwine with environmental and social impacts. This study investigates the interplay between sustainable food strategies and rebound effects, which refer to the reduced ef
Collateralized Loan Obligations (CLOs) are non-bank entities securitizing high-yield loans and trading these on secondary markets. They are decisive for the functioning of the leveraged loan market and therefore refinancing opportunities of firms. We assess how CLOs change their trading behavior when public attention to climate change rises. We find that CLOs increase exposure to high emission loa
The Paris Agreement sets the goal of a complete global phase-out of fossil fuel use by the end of the 21st century and an 80-95% reduction of carbon emissions in affluent countries by 2050. Obviously, efficiency gains alone cannot deliver the required reductions (Alfredsson et al. 2018), due to rebound effects (York, Adua, and Clark 2022) and the increasing pace of growth (Hickel 2020). It is sugg
With the migration from traditional news media to social media, understanding how citizens learn about politics and current affairs from these sources has become increasingly important. The use of social networking sites has become fully integrated into the strategies of political parties. Visualizations of political communication are becoming increasingly available across a variety of platforms a
Athymic Nude Rat Brain Atlas will provide the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient rat model commonly used in experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal, and horizontal brain sections of an athymic rat brain rendered from a single cleared specimen, placed in a compu
Background: Huntington’s disease (HD) is a motor and cognitive neurodegenerative disorder due to prominent loss of striatal medium spiny neurons (MSNs). Cell replacement using human embryonic stem cells (hESCs) derivatives may offer new therapeutic opportunities to replace degenerated neurons and repair damaged circuits. Methods: With the aim to develop effective cell replacement for HD, we assess
To link geophysical field data to specific biological phenomena, controlled laboratory experiments are needed for the understanding of the response of geophysical parameters to changes in biological conditions. In this study, suspensions of bacteria were mixed with sand to create a biofilm growing on a surface and these mixtures were monitored using the geoelectrical spectral induced polarization
Publicering av delar av forskningsprojektet Tång + Keramik + Textil, om tångens olika uttrycksformer, projektet undersöker och problematiserar tångens roll genom dess uttryck och materialitet.
This chapter is a commentary on Principle 1 of the Principles for Responsible Contracts (PRC). The PRC were endorsed by the United Nations Human Rights Council in 2011 alongside the United Nations Guiding Principles on Business and Human Rights. The PRC were drafted because of the potential for investment contracts to act as an instrument through which States and businesses could affect the human
Sweden has during the past decades experienced increasing challenges in suburban, segregated areas: the inhabitants have different cultural and socio-economic backgrounds but despite that, face similar problems. Many inhabitants lack relevant networks as well as other opportunities to become a part of the society. These inhabitants claim they don´t have the “keys” to understand their society and iSweden has during the past decades experienced increasing challenges in suburban, segregated areas: the inhabitants have different cultural and socio-economic backgrounds but despite that, face similar problems. Many inhabitants lack relevant networks as well as other opportunities to become a part of the society. These inhabitants claim they don´t have the “keys” to understand their society and i
Introduction: Pelvic girdle pain during and after pregnancy is a major public health problem with significant daily problems for affected women and their families. There is now accumulating evidence that pregnancy-related pelvic girdle pain originates from the sacroiliac joints and the pubic symphysis as well as their extra-articular ligaments. However, the heritability of the disease remains to b
Computational notebooks (e.g. Jupyter notebook) are a popular choice for interactive scientific computing to convey descriptive information together with executable source code. The user can annotate the scientific development of the work, the methods applied, describe ancillary data or the analysis of results, with text, illustrations, figures, and equations. Such ‘executable’ documents provide a
