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Intrathymic development of committed progenitor (pro)-T cells from multipotent hematopoietic precursors offers an opportunity to dissect the molecular circuitry establishing cell identity in response to environmental signals. This transition encompasses programmed shutoff of stem/progenitor genes, upregulation of T cell specification genes, proliferation, and ultimately commitment. To explain thes
Entropy production is a key concept of thermodynamics and allows one to analyze the operation of engines. For the Scovil-Schulz-DuBois heat engine, the archetypal three-level thermal maser coupled to thermal baths, it was argued that the common definition of heat flow may provide negative entropy production for certain parameters [Boukobza and Tannor, Phys. Rev. Lett. 98, 240601 (2007)PRLTAO0031-9
Catalytic breakdown of polysaccharides can be achieved more efficiently by means of the enzymes lytic polysaccharide monooxygenases (LPMOs). However, the LPMO mechanism has remained controversial, preventing full exploitation of their potential. One of the controversies has centered around an active site tyrosine, present in most LPMO classes. Recent investigations have for the first time obtained
Dryland ecosystems are a major source of land cover, account for about 40% of Earth's terrestrial surface and net primary productivity, and house more than 30% of the human population. These ecosystems are subject to climate extremes (e.g. large-scale droughts and extreme floods) that are projected to increase in frequency and severity under most future climate scenarios. In this modelling study w
En forskningsmässigt uppdaterad översikt av Tutankhamon och hans tid i skuggan av den fornegyptiska historien i allmänhet och Akhenatons politisk-religiösa reform i synnerhet.
Om gangsterväldet i New och Chicago på 1920-talet, med utblickar mot den historiska bakgrunden och maffians verksamhet senare under 1900-talet.
En översikt av häxförföljelser från antiken till nutiden, med fokus på europeisk tidigmodern tid.
En biografi om den svenska 1600-talsdrottningen Kristina.
Kopplingen mellan islamiska riksorganisationer och Centerpartiet går decennier tillbaka, skriver Sameh Egyptson, forskare i interreligiösa relationer. Partiet har fungerat som inkörsport och ett mål för infiltration från islamistiskt håll.
Att organisationer som anklagas för ekonomisk brottslighet utreder sig själva och fortsätter sitta på sina positioner är anmärkningsvärt. Det visar på ett förakt mot skattebetalarna.
Fuel and load flexibility have been increasingly important features of industrial gas turbines in order to meet the demand for increased utilization of renewable fuels and to provide a way to balance the grid fluctuations due to the unsteady supply of wind and solar power. Experimental investigations were performed using a standard 3rd generation dry low emission (DLE) burner under atmospheric pre
Efter flertalet uppmärksammade skandaler bör Centerpartiet föra ett ordentligt internt samtal om tolkningen av religionsfrihetslagen och om stödet till islamistiska organisationer.
Using x-ray photoelectron spectroscopy of the oxygen 1s core level, the ratio between intact (D2O) and dissociated (OD) water in the hydrated stoichiometric TiO2(110) surface is determined at varying coverage and temperature. In the submonolayer regime, both the D2O:OD ratio and the core-level binding energy of D2O (ΔBE) decrease with temperature. The observed variations in ΔBE are shown with dens
Det räcker med tjugo år av allmänna medel till en studieorganisation som sprider rasism, judehat och homofobi.
Folkbildningsrådets argumentation visar att de saknar kunskap om Muslimska brödraskapets ideologi och teologi.
Det är dags att Socialdemokraterna erkänner sina misstag, stoppar sitt stöd till islamister och stänger de skattefinansierade islamiska skolorna.
The effect of a Rotating Gliding Arc (RGA) plasma discharge on the flame in a scaled Siemens Dry Low Emission (DLE), SGT-750, burner was experimentally investigated under atmospheric combustion conditions. The central pilot section of the burner, named RPL (rich pilot lean), was redesigned with an integrated high voltage electrode to generate an RGA. The exhaust gas was sampled and analysed in ter
Mast cells play an important role in asthma, however, the interactions between mast cells, fibroblasts and epithelial cells in idiopathic pulmonary fibrosis (IPF) are less known. The objectives were to investigate the effect of mast cells on fibroblast activity and migration of epithelial cells. Lung fibroblasts from IPF patients and healthy individuals were co-cultured with LAD2 mast cells or sti
Corporate Social Responsibility (CSR) is regarded as an effort to be undertaken by the businesses to contribute towards society at large positively. The idea behind the concept of CSR is that businesses are required to pursue the notion of pro-social objectives along with economic objectives. Research has long established that corporate social responsibility, along with its philanthropic nature, c
Purpose: To evaluate the outcome of referrals for suspected glaucoma based on elevated intraocular pressure (IOP) made by optometric practitioners in Sweden. Methods: This prospective study included 95 individuals referred to the Skåne University Hospital Malmö, Sweden, during 2019, by optometric practitioners, based on elevated IOP. Positive outcome was defined as a diagnosis of glaucoma, or a di
