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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy

Background: Progressive accumulation of α-synuclein is a key step in the pathological development of Parkinson's disease. Impaired protein degradation and increased levels of α-synuclein may trigger a pathological aggregation in vitro and in vivo. The chaperone-mediated autophagy (CMA) pathway is involved in the intracellular degradation processes of α-synuclein. Dysfunction of the CMA pathway imp

An in-situ XANES investigation of the interactions between iron, manganese and antimony in silicate melts

The analysis of iron, manganese and antimony in silicate glass is of great interest in chemistry, materials science, earth sciences and archaeological sciences. Yet, conclusions from different fields appear to be contradictory and many questions about redox reactions in glass remain. The purpose of this study is thus to discuss whether and how these multivalent elements interact in glass. Soda-lim

Photoinduced electron transfer in a molecular dyad by nanosecond pump-pump-probe spectroscopy

The design of robust and inexpensive molecular photocatalysts for the conversion of abundant stable molecules like H 2 O and CO 2 into an energetic carrier is one of the major fundamental questions for scientists nowadays. The outstanding challenge is to couple single photoinduced charge separation events with the sequential accumulation of redox equivalents at the catalytic unit for performing m

ASEAN Voices (e100, 2017) for erhu and 10 mixed ASEAN ensemble players

#100. ASEAN Voices, for erhu and 10 mixed ASEAN ensemble players (2017). Premiere: Premiered by C asean Consonant (an ASEAN traditional ensemble), during the 2017 China-ASEAN Music Week at the Guangxi University of the Arts on May 27, 2017. The conductor was Knote KnocKnote with erhu soloist Hu Liu.