High-order harmonic generation (HHG) in gases has been established as an important technique for the generation of coherent extreme ultraviolet (XUV) pulses at ultrashort time scales. Its main drawback, however, is the low conversion efficiency, setting limits for many applications, such as ultrafast coherent imaging, nonlinear processes in the XUV range, or seeded free electron lasers. Here we in

Metalworking fluid (MWF) aerosols are associated with respiratory disorders including asthma and hypersensitivity pneumonitis. The aims of this study were to describe exposure to inhalable MWF aerosols and volatile compounds in machine shops, to estimate the influence of important determinants of exposure and to compare different sampling techniques for MWF aerosols. Personal full-shift air sample

There is an urgent need for biomarkers to enable early diagnosis of Alzheimer's disease (AD). It has recently been shown that a variant within the clusterin gene is associated with increased risk of AD and plasma levels of clusterin have been found to be associated with the risk of AD. We, therefore, investigated the diagnostic value of clusterin by quantifying clusterin using an ELISA in plasma f

Popular Abstract in Swedish Fysisk aktivitet har sedan länge sammankopplats med stark benstomme och stark muskulatur. Andra studier visar att hög fysisk aktivitet möjligen ger upphov till fler olyckor och frakturer. Man vet inte heller om ökad idrott i en oselekterade grupp med barn, inkluderande även de som inte gillar idrott, kan påverka skelettet och muskulaturen positivt. Bunkeflostudien, ellePhysical Activity (PA) can improve neuromuscular development. A high level of physical activity can perhaps however lead to more fractures. This is a longitudinal population-based exercise intervention study where the school-based physical education (PE) in one school is increased from mean 60 min/week to mean 200 min/ week. We registered fractures in all children during 6 years. We annually measu

Nurr1 is a nuclear hormone receptor (NucHR) strongly implicated in the growth, maintenance, and survival of dopaminergic neurons. Nurr1 may be unable to bind ligands directly, but it forms heterodimers with other NucHRs that do. Using bioluminescence resonance energy transfer (BRET) assays to directly monitor interactions of Nurr1 with other NucHRs, we found the cancer drug bexarotene (Targretin,

BACKGROUND: Restrictions in social and leisure activity can have negative consequences for the health and well-being of stroke survivors. To support the growing number of people who are ageing with stroke, knowledge is needed about factors that influence such activity in a long-term perspective. AIM: To identify long-term predictors of the frequency of social and leisure activities 10 years afte

Background Soft tissue massage is currently used in palliative care for the relief of anxiety and pain. Only few studies have focused on patients' deeper experience of receiving the massage. Aim The purpose of this study was to explore how patients with cancer in palliative home care experienced soft tissue massage. Materials and methods Twenty-two patients received soft tissue massage (hand or fo

Strong and independent associations between plasma concentration of cystatin C and risk of cardiovascular disease (CVD) suggests causal involvement of cystatin C.

Spruce chips steam-pretreated at various conditions, according to a central composite design, were used for investigating the influence of pretreatment conditions on enzymatic hydrolysis, accounting for the individual effects of pretreatment temperature (194-220°C), time (3-11min) and sulfur dioxide uptake (0.7-2.5%). The materials were analyzed for several surface characteristics, including IR ab

Background: Muscle function may influence the risk of knee injury and outcomes following injury. Clinical tests, such as a single-limb mini squat, resemble conditions of daily life and are easy to administer. Fewer squats per 30 seconds indicate poorer function. However, the quality of movement, such as the medio-lateral knee motion may also be important. The aim was to validate an observational c

Heavy neutron-rich nuclei were populated via the fragmentation of a E/A = 1 GeV Pb-208(82) beam. Secondary fragments were separated and identified and subsequently implanted in a passive stopper. By the detection of delayed gamma rays, isomeric decays associated with these nuclei have been identified. A total of 49 isomers were detected, with the majority of them observed for the first time. The n

Traumatic brain injury (TBI) has been shown to activate the peripheral innate immune system and systemic inflammatory response, possibly through the central release of damage associated molecular patterns (DAMPs). Our main purpose was to gain an initial understanding of the peripheral mitochondrial response following TBI, and how this response could be utilized to determine cerebral mitochondrial

Mounting evidence from proxy records suggests that variations in solar activity have played a significant role in triggering past climate changes. However, the mechanisms for sun-climate links remain a topic of debate. Here we present a high-resolution summer sea-surface temperature (SST) record covering the past 9300 yr from a site located at the present-day boundary between polar and Atlantic su

Cnidarians are often used as model animals in studies of eye and photopigment evolution. Most cnidarians display photosensitivity at some point in their life-cycle ranging from extraocular photoreception to image formation in camera-type eyes. The available information strongly suggests that some cnidarians even possess multiple photosystems. The evidence is strongest within Cubomedusae where all

The number of applications sharing the same embedded device is increasing dramatically. Very efficient mechanisms (resource managers) for assigning the CPU time to all demanding applications are needed. Unfortunately, existing optimization-based resource managers consume too much resource themselves. In this paper, we address the problem of distributed convergence to fair allocation of CPU resourc