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AIMS: The clinical usefulness of historical concentrations of high-sensitivity cardiac troponin T (hs-cTnT) is unknown. This study investigated the ability to rule out myocardial infarction (MI) with the use of historical hs-cTnT concentrations among patients with chest pain in the emergency department (ED).METHODS AND RESULTS: The derivation cohort consisted of patients presenting with chest pain
A circular economy (CE) calls for the value of materials and products to be maintained and recovered through narrowing, closing, and slowing loops. However, there remain challenges in capturing value through reuse of components in refurbished and repaired products. In this paper, we provide an overview of the research and practice of harvesting spare parts from used and waste electrical and electr
Corrosion in leak-tight plate structures, such as the containment liner in Nuclear Power Plants (NPPs), is detrimental to their operational state. To tackle this issue, the present work aims to assess the feasibility of using nonlinear ultrasound to detect corrosion. The corrosion product of main concern in the present study contains several microscopic and macroscopic cracks and delaminations. Th
This article contributes to debates on public sector innovation by empirically analysing and conceptually unpacking organizational resistance. It is based on research following the attempts to launch a particular public sector innovation, Social Impact Bonds (SIB), in Swedish local government. Drawing on the literature on productive resistance, the analysis shows how a range of different actors, f
Photoionization of atoms and molecules is one of the fastest processes in nature. The understanding of the ultrafast temporal dynamics of this process often requires the characterization of the different angular momentum channels over a broad energy range. Using a two-photon interferometry technique based on extreme ultraviolet and infrared ultrashort pulses, we measure the phase and amplitude of
SMAP/Sentinel-1 soil moisture is the latest SMAP (Soil Moisture Active Passive) product derived from synergistic utilization of the radiometry observations of SMAP and radar backscattering data of Sentinel-1. This product is the first and only global soil moisture (SM) map at 1 km and 3 km spatial resolutions. In this paper, we evaluated the SMAP/Sentinel-1 SM product from different viewpoints to
Recent advances have extended the scope of Bayesian optimization (BO) to expensive-to-evaluate black-box functions with dozens of dimensions, aspiring to unlock impactful applications, for example, in the life sciences, neural architecture search, and robotics. However, a closer examination reveals that the state-of-the-art methods for high-dimensional Bayesian optimization (HDBO) suffer from degr
Objective: To develop a method for detection of bradycardia and ventricular tachycardia using the photoplethysmogram (PPG). Approach: The detector is based on a dual-branch convolutional neural network (CNN), whose input is the scalograms of the continuous wavelet transform computed in 5-s segments. Training and validation of the CNN is accomplished using simulated PPG signals generated from RR in
Solid-state properties of dried protein formulations are important for stability and functionality of the product. This study investigates how different drying technologies (freeze-drying with and without annealing, spray drying and spray-freeze drying) affect the structure and solid-state properties of a set of matrix formulations composed of trehalose (glass former) and mannitol (scaffolding age
Reconstruction of movement control properties of the brain could result in many potential advantages for application in robotics. However, a hampering factor so far has been the lack of knowledge of the structure and function of brain circuitry in vivo during movement control. Much more detailed information has recently become available for the area of the cerebellum that controls arm-hand movemen
Plant development is regulated by transcription factors that often act in more than one process and stage of development. Yet the molecular mechanisms that govern the functional diversity and specificity of these proteins remains far from understood. Flower development provides an ideal context to study these mechanisms since the development of distinct floral organs depends on similar but distinc
Background: Around 70% of all ICU patients are treated with antibiotics whereas up to 30% are suggested as unnecessary. Measuring antibiotic consumption is a prerequisite to improving its use and the purpose of the present investigation was to explore the use of antibiotics in Swedish ICUs. Material and methods: Daily Defined Doses (DDDs) of antimicrobials delivered to Swedish ICUs, 2016–2018, wer
Jet impingement cooling was investigated on a flat heating surface placed in a flow channel, including single jet cooling, in-line double jet cooling, and combined crossflow and jet cooling; cross-flow cooling was a baseline for comparison. In addition, the in-line double jet cooling was explored with various jet distances. Local Nusselt number distribution was experimentally achieved by the liqui
This paper highlights changes in perceived room for agency and local institutions (formal and informal) in old Swedish mill regions. The paper draws on recent literature on change agency (Grillitsch & Sotarauta, 2020) and reproductive agency (Bækkelund, 2021; Jolly et al., 2020) as well as the role of institutions in local communities (Bole, 2021; Rodríguez-Pose, 2013) and builds on material f
Aim: To investigate school nurses’ experiences of health-promoting work to prevent stress in Swedish adolescents. Materials and methods: Swedish school nurses (n = 225) responded to a web survey with open-ended questions. The results were subjected to a qualitative content analysis. Results: Six categories were identified from the analysis: (1) Knowledge of body and soul, (2) Identifying stress an
Objective: To estimate the genetic contribution to doctor-diagnosed hand osteoarthritis (OA). Methods: Using data from the Swedish Twin Registry and National Patient Register, we conducted a 20-year population-based longitudinal cohort study including 59,970 twins aged 35 years or older. We studied inpatient and outpatient doctor-diagnosed hand OA using ICD-10 codes from 1997 until 2016, including
