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Background: Bone erosions may appear early or later during rheumatoid arthritis (RA), causing joint damage and functional impairment. However, in some patients erosions do not occur, even after several years of disease. This study evaluates the prevalence, clinical relevance and possible predictors of erosion-free RA. Methods: Six hundred and eight patients from an early RA cohort (BARFOT) having
The Gaia spacecraft presents an unprecedented opportunity to reveal the population of long period (a > 1 au) exoplanets orbiting stars across the H-R diagram, including white dwarfs. White dwarf planetary systems have played an important role in the study of planetary compositions, from their unique ability to provide bulk elemental abundances of planetary material in their atmospheres. Yet, very
Context. Phosphorus (P) is considered to be one of the key elements for life, making it an important element to look for in the abundance analysis of spectra of stellar systems. Yet, only a select number of spectroscopic studies exist to estimate the phosphorus abundances and investigate its trend across a range of metallicities. This is due to the lack of good phosphorus lines in the optical wave
We present the analysis of a spectroscopic secondary eclipse of the hottest transiting exoplanet detected to date, KELT-9b, obtained with the Wide Field Camera 3 aboard the Hubble Space Telescope. We complement these data with literature information on stellar pulsations and Spitzer/Infrared Array Camera and Transiting Exoplanet Survey Satellite eclipse depths of this target to obtain a broadband
Context. The Gaia-ESO Survey (GES) is a large public spectroscopic survey that was carried out using the multi-object FLAMES spectrograph at the Very Large Telescope. The survey provides accurate radial velocities, stellar parameters, and elemental abundances for ~115 000 stars in all Milky Way components. Aims. In this paper, we describe the method adopted in the final data release to derive lith
We present an upgraded version of the mocca code for the study of dynamical evolution of globular clusters (GCs) and its first application to the study of evolution of multiple stellar populations. We explore initial conditions spanning different structural parameters for the first (FG) and second generation of stars (SG) and we analyse their effect on the binary dynamics and survival. Here, we fo
Context. The chemical makeup of a star provides the fossil information of the environment where it formed. Under this premise, it should be possible to use chemical abundances to tag stars that formed within the same stellar association. This idea - known as chemical tagging - has not produced the expected results, especially within the thin disk where open stellar clusters have chemical patterns
The structural addictive characteristics of gambling products are important targets for prevention, but can be unintuitive to laypeople. In the PictoGRRed (Pictograms for Gambling Risk Reduction) study, we aimed to develop pictograms that illustrate the main addictive characteristics of gambling products and to assess their impact on identifying the addictiveness of gambling products by laypeople.
The Baltic Sea coast is a primary recreation and tourism space for both Swedish population and incoming tourists, not least from neighboring countries. Depending on the geographical preconditions, activities in the littoral zone comprise both typical beach activities and boating, and bohemian lifestyle. Second homes are a common form of accommodation, attracting Swedes to the shore during summer- The Baltic Sea coast is a primary recreation and tourism space for both the Swedish population and incoming tourists, not least from neighbouring countries. Depending on the geographical preconditions, activities in the littoral zone comprise both typical beach activities and boating, and bohemian lifestyle. Second homes are a common form of accommodation, attracting Swedes to the shore during sum
The frst May Measurement Month (MMM) campaign, a global blood pressure (BP) screening programme, began in 2017 as an initiative of the International Society of Hypertension.1 Two subsequent annual campaigns have also been completed in consecutive years2,3 and having had to defer activities due to the COVID-19 pandemic in 2020 the fourth campaign was run in 2021, the results of which are currently
Cardiovascular disease (CVD) remains one of the leading causes for increased morbidity and mortality in chronic kidney disease (CKD). Kidney transplantation is the preferred treatment option for CKD G5. Improved perioperative and postoperative care, personalized immunosuppressive regimes, and refined matching procedures of kidney transplants improves cardiovascular health in the early posttranspla
Current visual text analysis approaches rely on sophisticated processing pipelines. Each step of such a pipeline potentially amplifies any uncertainties from the previous step. To ensure the comprehensibility and interoperability of the results, it is of paramount importance to clearly communicate the uncertainty not only of the output but also within the pipeline. In this paper, we characterize t
Increased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been deIncreased platelet destruction is central in the pathogenesis of immune thrombocytopenia. However, impaired platelet production is also relevant and its significance underlies the rationale for treatment with thrombopoietin receptor agonists (TPO-RAs). Previous studies have associated enhanced complement activation with increased disease severity. Additionally, treatment refractoriness has been de
Growing global demand for extractive resources, such as metals and minerals, particularly to produce low-carbon products, requires international society to develop effective global governance mechanisms to mitigate some of the environmentally and socially negative impacts of mining operations beyond national borders. Since early 2000, several transnational extractive governance initiatives (TEGI)
This paper investigates an integrated traffic environment modeling and model predictive control (MPC) system to realize interaction-aware dynamic motion planning of an autonomous vehicle with multiple surrounding vehicles. The interaction-aware interacting multiple model Kalman filter (IAIMM-KF) from the literature is used to hierarchically predict maneuvers and trajectories of surrounding vehicle
China became one of the biggest players in the global extractive resource supply chain, along with increasing extractive resource demand for green industries. Interestingly, over the last two decades, Chinese actors started participating in transnational extractive governance initiatives (TEGI) supporting transparency, a norm for governance-by-disclosure. This article aims to answer the question o
