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Objective: To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC).Methods: Retrospective and prospective patients' data on all aspects of TSC were collected from multiple countries worldwide. Epilepsy variables included seizure type, age a
Essentials Protein S and FV-Short are synergistic cofactors to Tissue Factor Pathway Inhibitor α (TFPIα). An assay for the TFPIα synergistic cofactor activity of protein S with FV-Short was developed. The assay was specific for the synergistic TFPIα-cofactor activity of free protein S. Protein S deficient individuals with known mutations were correctly distinguished from controls. Summary: Backgro
Background: Reduced dexterity is common after stroke, which can affect the ability to perform upper limb daily activities. To improve upper limb function after stroke, it is important to understand which factors are most associated with dexterity. Objective: To evaluate how several factors are associated with dexterity after stroke. Design: Cross-sectional study. Setting: A university hospital. Pa
Photovoltaics is amongst the most important technologies for renewable energy sources, and plays a key role in the development of a society with a smaller environmental footprint. Key parameters for solar cells are their energy conversion efficiency, their operating lifetime, and the cost of the energy obtained from a photovoltaic system compared to other sources. The optimization of these aspects
In this report, we present a novel modular approach to the immobilization of a high density of boronic acid ligands on thermoresponsive block copolymer brushes for effective enrichment of glycoproteins via their synergistic multiple covalent binding with the immobilized boronic acids. Specifically, a two-step, consecutive surface-initiated atom transfer radical polymerization (SI-ATRP) was employe
Organometal halide perovskites have attracted tremendous attention for optoelectronic applications. Charge carrier trapping is one of the dominant processes often deteriorating the performance of devices. Here, we investigate the details of trap behavior in colloidal nanoparticles (NPs) of CH3NH3PbBr3 perovskites with mean size of 8 nm and the corresponding bulk crystals (BCs). We use excitation i
This book provides the first comprehensive discussion of conflicts between legal bases in EU law. It fills an important gap in the existing literature on the choice of legal basis in EU law by analysing the structure of legal bases and the resulting legal basis litigation in the European Union, thus identifying areas of conflict produced by overlapping competences, divergent inter-institutional in
This paper explains how corporations can develop market-based activities to influence environmental policies. The empirical focus is on how Swedish apparel retailers qualify take-back systems for used clothes and textiles as steps toward creating circular fashion. An analysis of the qualities that retailers attach to take-back systems shows how qualification helps corporations feature fashion as p
Context. Top-down chemistry is believed to be responsible for the formation of the large molecular compounds such as the polycyclicaromatic hydrocarbon-like molecules and the fullerenes observed in the interstellar medium. The release of these large molecules fromthe parent grains remains an important issue to be investigated.Aims. Cosmic rays irradiate the dust grains during their journey in the
This article analyses the impact of Brexit on devolved competences in environmental protection. It maps the post-Brexit division of the United Kingdom (UK)’s internal (devolved) and external (international) competences and how this may shift when competences are returned from the European Union (EU). Crucially, the article suggests that certain of these EU powers do not simply derive from the EU b
Signal processing complexity and required memory become problematic in massive MIMO systems as the dimension of channel state information (CSI) matrix grows significantly with the large number of antennas and users. To address these challenges, we propose the first angular-domain massive MIMO detection scheme, which is based on three concepts: transferring the baseband processing from the spatial
A considerable part of latency in the baseband of massive multiple-input multiple-output (MIMO) systems is introduced by orthogonal frequency division multiplexing (OFDM) (de)modulation. To address the low-latency demand of massive MIMO systems, a fast Fourier transform (FFT) processor and corresponding reordering scheme are proposed, which reduce the processing latency and reordering latency of O
Objective: To evaluate the hemostatic system in patients undergoing surgery for acute type A aortic dissection (ATAAD) compared with those undergoing elective aortic procedures. Design: This was a prospective, observational study. Setting: The study was performed at a single university hospital. Participants: Twenty-five patients with ATAAD were compared with 20 control patients undergoing electi
Eye tracking is a useful tool when studying the oscillatory eye movements associated with nystagmus. However, this oscillatory nature of nystagmus is problematic during calibration since it introduces uncertainty about where the person is actually looking. This renders comparisons between separate recordings unreliable. Still, the influence of the calibration protocol on eye movement data from peo
An integral equation-based numerical method for scattering from multi-dielectric cylinders is presented. Electromagnetic fields are represented via layer potentials in terms of surface densities with physical interpretations. The existence of null-field representations then adds superior flexibility to the modeling. Local representations are used for fast field evaluation at points away from their
Advanced combustion such as the partially premixed combustion (PPC) is characterized by high energy efficiency. However, they are sensitive to the inlet condition and injection of a combustion engine. Therefore, it is essential to use combustion feedback. The accuracy of the feedback variables, derived from the cylinder pressure signal, is crucial for effective combustion feedback control. This pa
The importance of semi-arid ecosystems in the global carbon cycle as sinks for CO 2 emissions has recently been highlighted. Africa is a carbon sink and nearly half its area comprises arid and semi-arid ecosystems. However, there are uncertainties regarding CO 2 fluxes for semi-arid ecosystems in Africa, particularly savannas and dry tropical woodlands. In order to improve on existing remote-se
