At present our knowledge of enteric peptide-containing neurons in man is limited. In this study we have used human appendices removed at surgery to examine the peptidergic innervation by immunocytochemistry, immunochemistry, and pharmacological in vitro experiments. Immunocytochemistry revealed a variety of peptide-containing nerve fiber populations in the human appendix. VIP/PHI-, VIP/PHI/NPY-, S

Computed tomography (CT) was performed in 9 patients with faecal incontinence more than 8 years after rectoplasty for high imperforate anus. The radiologic findings were correlated with the clinical evaluation of faecal incontinence. No statistically significant correlation was found between function and anatomic findings as demonstrated by CT. Thus, although CT demonstrates the post-operative ana

Computerised tomography and magnetic resonance tomography were performed in nine faecally incontinent patients more than eight years after rectoplasty for high imperforate anus. No statistically significant correlation was found between function, i. e. degree of faecal incontinence, and anatomical findings. Thus, in spite of a detailed demonstration of the post-operative anatomy, the information d

This paper reports on two cases of incarcerated congenital diaphragmatic hernia presenting as intestinal obstruction without any signs or symptoms or respiratory tract illness.

Open testicular wedge biopsy has electively been performed prior to completion of maintenance therapy for acute lymphoblastic leukemia. 25 boys during 6 years were included in this prospective study. Three boys developed testicular enlargement while on maintenance therapy and biopsies confirmed testicular leukemia. The remaining 22 boys were biopsied at termination of maintenance therapy. Occult t

Domestic social capabilities are a set of national characteristics for understanding why some countries grow faster than others. Yet there is no clear agreement on the main characteristics of these capabilities and therefore they have been neglected in the income convergence debate. The paper presents an index for revisiting the role of social capabilities in this debate. A relatively socially adv

In this paper, we inductively explore how within-firm goal conflict influences inter-firm collaboration over time. Based on our findings, we challenge current theorizing on collaborative dynamics in inter-organizational relationships, positioning firms as polilithic entities, where within-firm goal conflict can spur complex and unexpected between-firm collaborative processes and outcomes.

Today's IT organizations must ensure that IT services are aligned to business needs and actively support ongoing business processes. This means that internal IT service management processes are under constant improvement. However, to be able to know if the IT service provision develops in the right direction, there is a need to perform some kind of self-assessment of IT process maturity. In this p

It is clear that the formal inclusion of the national parliament as a political actor within the EU decision-making process has been one of the most important innovations of the Lisbon Treaty.Their role, however, remains controversial. It is on the one hand disputed whether national parliaments enjoy sufficient powers to tame'competence creep’. On the other hand, it is contested to what extent it

Flying insects are of utmost importance in ecology and for human living conditions. Certain species serve as indispensable pollinators to ensure the availability of food stuffs, while others are dangerous vectors for spreading deadly diseases, such as malaria. Agricultural pests reduce the yield of crops, and their abatement through pesticides cause many additional problems. Birds and bats are fre

The human host defense peptide LL-37 possesses antimicrobial activity but also affects host cell function and viability. Mast cells are involved in innate immunity but no data have been presented on effects of LL-37 on human mast cell viability and export of nucleic acids. Here, we demonstrated by immunofluorescence microscopy that synthesized LL-37 was internalized by human LAD2 mast cells and de

Digital activism, political activism mediated by digital technologies, offers the promise of increased visibility and political power for marginalized groups. Yet, this has not been the case outside of a few exceptions such as Black Lives Matter. This paper offers theoretical, conceptual critical research that explores why successful digital activism may elude marginalized groups. We ask why many

The integration of III-V semiconductors with Si in device fabrication is facilitated by the use of nanoscale structures such as nanowires. Nanowires are predominantly grown using Au seed particles; however, the seed material is known to affect the nanowire growth and properties. Here we present growth of GaAs nanowires using three different seed particle materials: Au, Ag, and a AgAu alloy. By com

In the past years Centers of Excellence (CoE) has risen to prominence as a funding instrument in science. The idea is that by focusing resources, people and attention within a center environment, and over a substantial time span, excellence in science can be promoted. Similarly, interdisciplinarity is often seen as an enabling condition or even necessary for frontier research. This article builds

Introduction: Cardiac syncope heralds significantly higher mortality compared with syncope due to noncardiac causes or unknown etiology, commonly considered a benign event. A few epidemiologic studies have examined the outcome of noncardiac/unexplained syncope comparing individuals with and without syncope, but with controversial results. We performed a systematic review and meta-analysis to clari

Age-related macular degeneration (AMD) is a progressive disease of the central retina and the leading cause of irreversible vision loss in the western world. The involvement of abnormal complement activation in AMD has been suggested by association of variants in genes encoding complement proteins with disease development. A low-frequency variant (p.P167S) in the complement component C9 (C9) gene

The first step of the adaptive immune response involves the interaction of T cells that express T-cell receptors (TCRs) with peptide-loaded major histocompatibility complexes expressed by antigen-presenting cells (APCs). Exactly how this leads to activation of the TCR and to downstream signaling is uncertain, however. Recent findings suggest that one of the key events is the exclusion of the large

The use of wood as construction material in multi-story buildings increased in Europe during the last decades. Wood buildings are more sensitive to dynamic loading compared to conventional concrete buildings, especially in terms of vibroacoustic comfort. Furthermore, it is more difficult to predict the accurate response due to dynamic loading for wood buildings. This is due to factors such as a co