Planetary boundaries are either being approached or already crossed, and there is no evidence for an absolute decoupling of GDP growth, resource use and greenhouse gas emissions. How economic and social systems may be reembedded into environmental limits in the absence of growth is a crucial issue within and beyond economics. This paper outlines some of the elements and analytical steps that may t

Wind energy is an important field of development for the island of Gotland, Sweden, especially since the island has set targets to generate 100% of its energy from renewable sources by 2025. Due to the variability of wind conditions, energy storage will be an important technology to facilitate the continued development of wind energy on Gotland and ensure a stable and secure supply of electricity.

The ecosystem services approach can inform decision-making by accounting for both short- and long-term benefits from different land use options. Here we used the InVEST toolkit to quantify and map key ecosystem services at the largest publicly-owned agro-silvo-pastoral farmstead in Portugal–a site representative for the montado landscape. We analyzed how Provisioning (cork production) and Regulati

BACKGROUND: Registry-based randomized clinical trials have emerged as useful tools to provide evidence on the comparative efficacy and safety of different therapeutic strategies. However, it remains unknown whether the results of registry-based randomized clinical trials have a sizable impact on daily clinical practice. We sought, therefore, to describe the temporal trends in thrombus aspiration (

Objectives To assess whether chronic kidney disease of unknown aetiology (CKDu) is present in India and to identify risk factors for it using population-based data and standardised methods. Design Secondary data analysis of three population-based cross-sectional studies conducted between 2010 and 2014. Setting Urban and rural areas of Northern India (states of Delhi and Haryana) and Southern India

The development of cancer is driven by the accumulation of many oncogenesis-related genetic alterations and tumorigenesis is triggered by complex networks of involved genes rather than independent actions. To explore the epistasis existing among oncogenesis-related genes in lung cancer development, we conducted pairwise genetic interaction analyses among 35,031 SNPs from 2027 oncogenesis-related g

The efficiency of the photon identification criteria in the ATLAS detector is measured using 36.1fb1 to 36.7fb1 of pp collision data at s=13 TeV collected in 2015 and 2016. The efficiencies are measured separately for converted and unconverted isolated photons, in four different pseudorapidity regions, for transverse momenta between 10 GeV and 1.5 TeV. The results from the combination of three dat

Purpose: The purpose of this paper is to determine associations between initially recorded deviations in individual bedside vital parameters that contribute to total Modified Early Warning Score (MEWS) levels 2 or 3 and further clinical deterioration (MEWS level=4). Design/methodology/approach: This was a prospective study in which 27,504 vital parameter values, corresponding to a total MEWS level

In this article, we study the fully differential observables of the exclusive production of heavy (charm and bottom) quark pairs in high-energy ultraperipheral pA and AA collisions. In these processes, the nucleus A serves as an efficient source of the photon flux, while the QCD interaction of the produced heavy-quark pair with the target (p or A) proceeds via an exchange of gluons in a color sing

A unification of left-right SU(3)L×SU(3)R, color SU(3)C, and family SU(3)F symmetries in a maximal rank-8 subgroup of E8 is proposed as a landmark for future explorations beyond the Standard Model (SM). We discuss the implications of this scheme in a supersymmetric (SUSY) model based on the trinification gauge [SU(3)]3 and global SU(3)F-family symmetries. Among the key properties of this model are

Extensively managed grasslands are recognized globally for their high biodiversity and their social and cultural values. However, their capacity to deliver multiple ecosystem services (ES) as parts of agricultural systems is surprisingly understudied compared to other production systems. We undertook a comprehensive overview of ES provided by natural and semi-natural grasslands, using southern Afr

Twenty years have passed since first light for the Sloan Digital Sky Survey (SDSS). Here, we release data taken by the fourth phase of SDSS (SDSS-IV) across its first three years of operation (2014 July-2017 July). This is the third data release for SDSS-IV, and the 15th from SDSS (Data Release Fifteen; DR15). New data come from MaNGA - we release 4824 data cubes, as well as the first stellar spec

Intergenerational mobility studies are now expanding in three directions – including different regions and time periods, using different outcomes to measure mobility, and investigating the mechanisms that affect mobility. We investigate, for the first time, wealth mobility in the Cape Colony. We compare a number of outcomes, and consider several mechanisms to explain our results. Our data allow us

The production yield of prompt D mesons and their elliptic flow coefficient v 2 were measured with the Event-Shape Engineering (ESE) technique applied to mid-central (10–30% and 30–50% centrality classes) Pb-Pb collisions at the centre-of-mass energy per nucleon pair sNN=5.02 TeV, with the ALICE detector at the LHC. The ESE technique allows the classification of events, belonging to the same centr

BACKGROUND: Most evidence for TSC-associated neuropsychiatric disorders (TAND) to date have come from small studies and case reports, and very little is known about TAND in adults. We explored baseline TAND data from the large-scale international TOSCA natural history study to compare childhood and adult patterns, describe age-based patterns, and explore genotype-TAND correlations.RESULTS: The stu

Objective: To present the baseline data of the international TuberOus SClerosis registry to increase disease Awareness (TOSCA) with emphasis on the characteristics of epilepsies associated with tuberous sclerosis complex (TSC).Methods: Retrospective and prospective patients' data on all aspects of TSC were collected from multiple countries worldwide. Epilepsy variables included seizure type, age a