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H-Diplo

Chester A. Crocker, Fen Osler Hampson and Pamela Aall, eds. Diplomacy and the Future of World Order. Washington DC: Georgetown University Press, 2021. IBSN: 9781647120931 (hardcover $110.95), 9781647120948 (paperback $36.95).

Associations of CSF PDGFRβ With Aging, Blood-Brain Barrier Damage, Neuroinflammation, and Alzheimer Disease Pathologic Changes

BACKGROUND AND OBJECTIVES: Injured pericytes in the neurovascular unit release platelet-derived growth factor β (PDGFRβ) into the cerebrospinal fluid (CSF). However, it is not clear how pericyte injury contributes to Alzheimer's disease (AD)-related changes and blood brain barrier (BBB) damage. We aimed to test if CSF PDGFRβ was associated with different AD- and age-associated pathological changes

High Prevalence of SARS-CoV-2 Omicron Infection Despite High Seroprevalence, Sweden, 2022

We performed 2 surveys during 2022 to estimate point prevalences of SARS-CoV-2 infection compared with overall viral seroprevalence in Sweden. Point prevalence was 1.4% in March and 1.5% in September. Estimated seroprevalence was >80%, including among unvaccinated children. Continued SARS-CoV-2 surveillance is necessary for detecting emerging, possibly more pathogenic variants.

Ivacaftor therapy post myocardial infarction augments systemic inflammation and evokes contrasting effects with respect to tissue inflammation in brain and lung

Acquired cystic fibrosis transmembrane regulator (CFTR) dysfunctions have been associated with several conditions, including myocardial infarction (MI). Here, CFTR is downregulated in brain, heart, and lung tissue and associates with inflammation and degenerative processes. Therapeutically increasing CFTR expression attenuates these effects. Whether potentiating CFTR function yields similar benefi

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Detta är en bearbetad version på nederländska av min tidigare på svenska utgivna biografi om den engelske kungen Henrik VIII.De Zweedse hoogleraar Dick Harrison vertelt het kleurrijke levensverhaal van Hendrik VIII (1491-1547). Hendrik werd, na de dood van zijn vader, de tweede Tudor-koning van Engeland. Hij leidde een roemrucht bestaan. Hij had zes echtgenotes, van wie hij er twee liet onthoofden. Hij scheidde, voor eigen gewin, de Anglicaanse kerk af van de Kerk van Rome, en hij verenigde Engeland en Wales wettelijk i

Well-being Processes : Insights into Personal Growth and Adolescent Mental Health

Denna avhandling belyser välbefinnandeprocesser utifrån två olika angreppssätt: 1)dels teoretiska beskrivningar av personligt växande, där personligt växandedefinieras som den gradvisa processen av förändring i välbefinnande, 2) delsempiriska undersökningar av välbefinnande och mental hälsa med fokus på eleversmentala hälsoprofiler och självuppfattning. Sammanlagt ingår fem studier iavhandlingen, This thesis follows two main lines of inquiry into well-being processes: 1) atheoretical exploration of personal growth, defined as the gradual growth of wellbeing, and 2) an empirical exploration of students’ mental health profiles and sense of self. Altogether five studies are included in the thesis, two of which follow thefirst line of inquiry (articles I and II) and three of which follow the s

Towards optimization of anomaly detection in DevOps

Context: DevOps has recently become a mainstream solution for bridging the gaps between development (Dev) and operations (Ops) enabling cross-functional collaboration. The DevOps concept of continuous monitoring may bring a lot of benefits to development teams such as early detection of run-time errors and various performance anomalies. Objective: We aim to explore deep learning (DL) solutions for

Hypothermic versus Normothermic Temperature Control after Cardiac Arrest

BACKGROUNDThe evidence for temperature control for comatose survivors of cardiac arrest is inconclusive. Controversy exists as to whether the effects of hypothermia differ per the circumstances of the cardiac arrest or patient characteristics.METHODSAn individual patient data meta-analysis of the Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest (TTM) and Hypothermia versus

Rethinking the Haitian Turn : Beyond the Universality Paradigm and Its Enemies

Recent assessments of the literature on the Haitian Revolution (1791–1804) offer radically different images, ranging from the identification of a politics of universal human rights to objections against conservative assumptions. The present article instead uncovers an overarching conflict between what is named the universality paradigm and the sceptical responses. However, in the outskirts of the

The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data

Open science and collaboration are necessary to facilitate the advancement of Parkinson’s disease (PD) research. Hackathons are collaborative events that bring together people with different skill sets and backgrounds to generate resources and creative solutions to problems. These events can be used as training and networking opportunities, thus we coordinated a virtual 3-day hackathon event, duri

Pain and labor outcomes : A longitudinal study of adults with cerebral palsy in Sweden

BACKGROUND: Pain is a global health concern with substantial societal costs and limits the activity participation of individuals. The prevalence of pain is estimated to be high among individuals with cerebral palsy (CP).OBJECTIVES: To estimate the association between pain and labor outcomes for adults with CP in Sweden.METHODS: A longitudinal cohort study based on data from Swedish population-base

Predictions of Spray Combustion using Conventional Category A Fuels and Exploratory Category C Fuels

Aviation currently contributes about 3% of the world’s CO2 emissions, 5% of the global warming, and 35% of the trade. Reducing the emissions and the global warming from aviation is thus essential. Many approaches to achieve this goal are underway, including H2, fuel cells, and batteries, but also by replacing the fossil jet fuel with sustainable jet fuel from non-fossil feedstocks. This involves m

Do Exporters Import Gender Inequality?

We examine whether exposure to gender inequality at export destinations affects the gender wage gap in exporting firms. We motivate the analysis through a stylized model where wages depend on worker productivity, and men have a comparative advantage when trading with gender-unequal countries due to customer discrimination. Empirically, we use high-quality matched employer-employee data from Sweden