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Detection of lymph node metastases in patients with prostate cancer : Comparing conventional and digital [18F]-fluorocholine PET-CT using histopathology as a reference

Background: Positron emission tomography-computed tomography (PET-CT) with [18F]-fluorocholine (FCH) is used to detect and stage metastatic lymph nodes in patients with prostate cancer. Improvements to hardware and software have recently been made. We compared the capability of detecting regional lymph node metastases using conventional and digital silicon photomultiplier (SiPM)-based PET-CT techn

Patient trajectories after diagnosis of diffuse large B-cell lymphoma—a multistate modelling approach to estimate the chance of lasting remission

Background: Achieving lasting remission for at least 2 years is a good indicator for favourable prognosis long term after Diffuse large B-cell lymphoma (DLBCL). The aim of this study was to provide real-world probabilities, useful in risk communication and clinical decision-making, of the chance for lasting remissions by clinical characteristics. Methods: DLBCL patients in remission after primary

International experience makes a difference: Effects of studying abroad on students' self-efficacy

The present study examined whether students experience an increase in their general perceived self-efficacythrough international academic mobility. Two hundred and twenty-one students at Leuphana UniversityLüneburg were enrolled in a test-retest study with two points of measurement including a time interval of ap-proximately six months. Perceived self-efficacy was measured in a group of sojourners

International sojourn experience and personality development: Selection and socialization effects of studying abroad and the Big Five

As part of a multi-study project, this test-retest study seeks to identify the relations between studying abroad anda sojourner's personality as measured by the Big Five personality traits. It thereby attempts to answer the ques-tions of who chooses to study abroad and how study abroad changes personality. A total of 221 students from aGermanuniversity weretracked over the courseofa semester, with

Return to Sports : A Risky Business? A Systematic Review with Meta-Analysis of Risk Factors for Graft Rupture Following ACL Reconstruction

Background: The risk of sustaining a graft rupture after anterior cruciate ligament reconstruction (ACLR) is high. Contributing risk factors are, however, still not clearly identified. Objective: The aim of this systematic review was to identify and quantify risk factors for graft rupture after ACLR. Methods: A systematic review with meta-analysis (PROSPERO CRD42020140129) based on PRISMA guidelin

Talking, Listening and Emancipation : A Heideggerian Take on the Peer-Relation in Self-Help

This paper adds a phenomenological account to the discussion on what constitutes the favorable prospects of the peer-relation in the context of self-help. By drawing on Heidegger’s lectures on St Paul’s First Thessalonians, and engaging in dialogue with a fictive case, we show that more attention needs to be given to how meaning is enacted, rather than simply adopted, in the peer-relation; that is

Evaluation of 3D printed contrast detail phantoms for mammography quality assurance

Objects created by 3D printers are increasingly used in various medical applications. Today, affordable 3D printers, using Fused Deposition Modeling are widely available. In this project, a commercially available 3D printer was used to replicate a conventional radiographic contrast detail phantom. Printing materials were selected by comparing their x-ray attenuation properties. Two replicas were p

Kidney outcomes in early adolescence following perinatal asphyxia and hypothermia-treated hypoxic-ischaemic encephalopathy

Background: Acute kidney injury (AKI) remains common among infants with hypothermia-treated hypoxic-ischaemic encephalopathy (HIE). Little is known about long-term kidney outcomes following hypothermia treatment. We recently reported that 21% of survivors of hypothermia-treated HIE had decreased estimated glomerular filtration rate (eGFR) based on plasma creatinine in early adolescence. Here, we a

Coastal aeolian sediment transport in an active bed surface layer : Tracer study and conceptual model

Coastal aeolian sediment transport is influenced by supply-limiting factors caused by sediment sorting by grain size. Sorting processes can lead to coarsening of the bed surface and influence the formation of aeolian ripples. However, the influence sorting processes and bedforms might have on the magnitude of the transport is not fully understood. This study explores sorting processes and their in

The impact of myocardial fibrosis biomarkers in a heart failure population with atrial fibrillation—The HARVEST-Malmö study

Background: Several studies suggest that circulating biomarkers of myocardial fibrosis are associated with worse prognosis in subjects with atrial fibrillation (AF). Here, we aimed to explore associations between fibrosis biomarkers, prevalent AF, and left atrial volume (LAV) enlargement in subjects with heart failure (HF). Additionally, we evaluated the prognostic impact of fibrotic biomarkers in

Solving Exact Cover Instances with Molecular-Motor-Powered Network-Based Biocomputation

Information processing by traditional, serial electronic processors consumes an ever-increasing part of the global electricity supply. An alternative, highly energy efficient, parallel computing paradigm is network-based biocomputation (NBC). In NBC a given combinatorial problem is encoded into a nanofabricated, modular network. Parallel exploration of the network by a very large number of indepen

REM-Predominant Obstructive Sleep Apnea in Patients with Coronary Artery Disease

Obstructive sleep apnea (OSA) is common in adults with coronary artery disease (CAD). OSA that occurs predominantly during rapid-eye movement (REM) sleep has been identified as a specific phenotype (REM-predominant OSA) in sleep clinic cohorts. We aimed to examine the association of REM-predominant OSA with excessive sleepiness, functional outcomes, mood, and quality of life in a CAD cohort, of wh

A Structured Optimal Controller for Irrigation Networks

In this paper, we apply an optimal Linear Quadratic (LQ) controller, which has an inherent structure that allows for a distributed implementation, to an irrigation network. The network consists of a water reservoir and connected water canals. The goal is to keep the levels close to the set-points when farmers take out water. The LQ controller is designed using a first-order approximation of the ca

Insulin secretion and action with increasing age - A comparison between Middle Eastern immigrants and native Swedes

Aims: Little is known how insulin secretion and action change over time in populations of different ethnicities. We studied changes in insulin secretion and action with increasing age in Iraqi-born immigrants and native Swedes, and investigated if the changes were modified by region of origin.Methods: Residents of Malmö, 30-75 years of age born in Iraq or Sweden, were invited to participate in thi

Effects of injection angle and injector mode variation on the fluidization performance of a powder-fueled ramjet

Fluidization is a major problem in the supply system of a powder-fueled ramjet. The performance of fluidization mainly depends on the injection way of fluidizing gas. This paper has investigated the effects of variation of the injection angles and injector modes on the performance of fluidization, using the Euler-Lagrange approach for gas-particle flow. The injection angle varies among 30°, 45°, 6

The challenge of recruiting multimorbid older patients identified in a hospital database to a randomised controlled trial

BACKGROUND: Research involving multimorbid older patients is gaining momentum. However, little is known about how to plan a randomised controlled trial (RCT) involving this group of patients. An evidence-based approach to the challenges of a recruitment process could guide researchers and help prevent underpowered trials.AIM: To define the number of multimorbid older patients that need to be ident

Introduction : Rigour and relevance in European entrepreneurship research

This introduction provides an overview and commentary on the main chapters in the book. The book presents contemporary examples of European research that embrace both rigour and relevance. In doing so, the book demonstrates that both rigour and relevance is alive in entrepreneurship research. Many of the following chapters address agendas that are influenced by pragmatic questions as much as theor