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Protein D, having a glycerol-3-phosphodiester phosphodiesterase activity, is found at the surface of all Haemophilus influenzae strains and is a possible virulence factor. In the present study, the involvement of protein D in the entry of NTHi into human monocytic cells is reported. Primary monocytes and the monocytic cell lines U-937 and THP-1 were infected with NTHi strain 772 and the mutant 772

As part of a multidisciplinary study, the rate of autism spectrum disorder (ASD), learning disability (LD), and brain abnormalities was examined in 20 participants (12 males, 8 females; age range 8mo-17y, mean age 8y 1mo) diagnosed as falling within the oculoauriculovertebral spectrum (OAV). A neuropsychiatric examination was performed, including standardized autism diagnostic interviews. Two indi

Radionuclides are used in nuclear medicine in a variety of diagnostic and therapeutic procedures. A knowledge of the radiation dose received by different organs in the body is essential to an evaluation of the risks and benefits of any procedure. In this paper, current methods for internal dosimetry are reviewed, as they are applied in nuclear medicine. Particularly, the Medical Internal Radiation

A simple labeling approach is presented based on protein expression in [1-C-13]- or [2-C-13]-glucose containing media that produces molecules enriched at methyl carbon positions or backbone C-alpha sites, respectively. All of the methyl groups, with the exception of Thr and Ile(delta 1) are produced with isolated C-13 spins (i.e., no C-13-C-13 one bond couplings), facilitating studies of dynamics

Growth kinetic data of human tumours, obtained by flow cytometric analysis of cells labelled with bromodeoxyuridine (BrdUrd) might provide prognostic information and allow prediction of response to radio- and chemotherapy. However, the theoretical models applied for calculation of growth kinetic data are not fully evaluated. The purpose of this study was to investigate the dependence of the estima

The oxidative ammonolysis of toluene, i.e., ammoxidation without the presence of molecular oxygen, was studied over a series of samples of MoO3 crystals. The specific surface areas of the various faces were determined from SEM micrographs. Correlations between activities and surface planes were found. For the formation of nitrile the specific activity decreased in the order {001} and {h01} > {100}

Aggressiveness during intersexual conflicts is predicted to depend on its costs, the value of winning and the power asymmetry of the contestants, all of which may vary between populations. In the marine isopod Idotea baltica (Pallas) a conflict occurs as females resist the attempts by males to start precopulatory mate guarding. We analysed contest dynamics with respect to female maturity stage, th

Transgenic Huntington's disease (HD) mice, expressing exon 1 of the human HD gene (lines R6/1 and R6/2), are totally resistant to striatal lesions caused by the NMDA receptor agonist quinolinic acid (QA). Here we show that this resistance develops gradually over time in both R6/1 and R6/2 mice, and that it occurred earlier in R6/2 (CAG-155) than in R6/1 (CAG-115) mice. The development of the resis

We have previously shown that the concentration of diphenylmethane-4,4'-diisocyanate (4,4'-MDI) in commercial test preparations was so low that patch testing with the same was not reliable. The stability of 4,4'-MDI in petrolatum (pet.) was compared with pet. preparations of polymeric diphenylmethane diisocyanate (PMDI), which consists of a complex mixture of monomeric isomers and oligomers of MDI

Background Relatives of breast cancer cases have an increased risk of the disease. The risk increases with increasing numbers and decreasing age of onset of affected relatives. In families with a BRCA1 or a BRCA2 mutation, individual carrier status predicts the risk of breast cancer. In relatives of cases where both BRCA1 and BRCA2 mutations are excluded, the risk remains undetermined. Methods Sta

Quantum ratchets are Brownian motors in which the quantum dynamics of particles induces qualitatively new behavior. We review a series of experiments in which asymmetric semiconductor devices of sub-micron dimensions are used to study quantum ratchets for electrons. In rocked quantum-dot ratchets electron-wave interference is used to create a non-linear voltage response, leading to a ratchet effec

The former winter sports camp Frostavallen was connected by a track to the nearest railway halt, now part of the Skaneleden subtrail Ridge to Ridge. Rubus echinatus, R. senticosus and R. sciocharis occur at three sites in the area, probably a result of timber import half a century ago.

The sand-steppe is a unique vegetation type almost exclusively found in eastern Scania. It is dominated by rare species such as Koeleria glauca, Festuca polesica, Phleum arenarium, Dianthus arenarius, Astragalus arenarius, Anthericum ramosum and Syntrichia ruraliformis. In 1994, the area covered by this vegetation was estimated to be 57 ha but in the present study only 20-30 ha were refound. Prere

The primary aim of the study was to estimate the spatial scale of pollen dispersal and deposition for pollen assemblages from moss polsters in the cultivated landscape of southern Sweden, as a mean to improve future studies of the pollen/vegetation relationship in the region, and interpretation of fossil pollen data in terms of past cultural landscapes. This can be done by estimating the 'relevant

A 5-year retrospective study of the frequency of sensitization to the 25 allergens of the European standard series (ESS) was conducted in 10 centres in 8 European countries. Included were the results of 26 210 patients. The range in sensitivities differed moderately between the centres. Combining results of different centres and drawing conclusions on incidences can be done only with great care. T

J/psi production has been measured in proton-proton collisions at roots=200 GeV over a wide rapidity and transverse momentum range by the PHENIX experiment at the Relativistic Heavy Ion Collider. Distributions of the rapidity and transverse momentum, along with measurements of the mean transverse momentum and total production cross section are presented and compared to available theoretical calcul

Adsorption of Co(II) at the aqueous interfaces of ZnO and ZnS (wurtzite) has been studied by classical wet-chemical methods, and the structure and composition of Co adsorption complexes at these interfaces have been determined by in-situ X-ray absorption fine structure (XAFS) spectroscopy. On both adsorbents, adsorption as a function of pH shows the normal behavior, i.e., a pronounced adsorption w