Recent studies have established distinctive serum polypeptide patterns through mass spectrometry (MS) that reportedly correlate with clinically relevant outcomes. Wider acceptance of these signatures as valid biomarkers for disease may follow sequence characterization of the components and elucidation of the mechanisms by which they are generated. Using a highly optimized peptide extraction and ma

One of the main issues for balance control is the ability to generate enough forces to execute motions and uphold stability. This study aimed to investigate whether induced fatigue of the triceps surae muscles and decreased muscle force due to temporary additional body weight affected the ability to withstand balance perturbations. Another aim was to examine whether postural control adaptation ove

PURPOSE: To compare thallium-201 single-photon emission CT with conventional CT in grading the malignancy of gliomas and to determine the reliability of each in tumor assessment. METHODS: We studied 37 patients who had gliomas (31 high grade and 6 low grade) and compared the CT findings with the thallium-201 index, which we defined as tumor uptake relative to the uptake in the contralateral hemisp

In a search for new fungal compounds inducing apoptosis of the colon cancer derived cell line COLO-320, hormonemate (1) was purified from fermentations of an endophytic fungus isolated from living needles of a Pinus species. The producing strain was identified as Hormonema dematioides by microscopy and ITS rDNA sequence analysis. The structure of hormonemate was determined by spectroscopic methods

The potential for pheromone-based mating disruption (MD) of Ephestia kuehniella (Walker) and Plodia interpunctella (Hübner) (Lepidoptera: Pyralidae) was investigated in two flour mills and a pet food distributor. Plastic sachets emitting 2–3 mg per d ( Z, E)-9,12-tetradecadienyl acetate, the major pheromone component of both moth species, were used as MD dispensers, which were applied in grid syst

To study the personality characteristics of adults with Asperger syndrome, and investigate the value of self-rating personality inventories, we administered the Temperament and Character Inventory (TCI) to 31 outpatients with Asperger syndrome.The TCI is a self-rating personality inventory that has been validated in the Swedish general population. The results were compared with age- and sex-matche

Transient wave propagation in a finite bi-isotropic slab is treated. The incident field impinges normally on the slab, which can be inhomogeneous wrt depth. Dispersion and bi-isotropy are modeled by time convolutions in the constitutive relations. Outside the slab the medium is assumed to be homogeneous, non-dispersive and isotropic, and such that there is no phase velocity mismatch at the boundar

Decline in pH and leakage of base cations have been recorded in beech forest soils in southern Sweden. This study investigated the influence of soil properties on frost sensitivity in beech bark and evaluated the effects on frost sensitivity of soil treatment with lime, wood ash or excessive N fertilization. Beech trees on five experimental sites were studied. The results indicated that beech tree

A novel design of a biochemical oxygen demand (BOD) biosensor has been developed for on-line monitoring of easily biodegradable organic compounds in aqueous samples. The biological recognition element of the sensor could be easily renewed by injecting new bacterial paste without disassembling the sensor system. The sensor measurements were carried out in the initial-rate mode using a flow injectio

This article investigates the relationship between universities and academic spin-offs, with special emphasis on the antecedent conditions of, and the nature of the linkages that the spin-offs form, as well as the means for sustaining them. The present research uses an instrumental case study approach, and is also an instance of a collective case study as four companies of various size and activit

Popular Abstract in Swedish Kroniskt Obstruktiv Lungsjukdom (KOL) är idag världens fjärde vanligaste dödsorsak vars dödlighetsfrekvens ökar. KOL är en lungsjukdom som nästan alltid beror på rökning och i hela världen är cirka 600 miljoner människor drabbade av sjukdomen. Detta gör KOL till världens vanligaste kroniska sjukdom. I Sverige beräknas sjukvårdskostnaderna för KOL att uppgå till ca 9,1 mProteomic analysis of bronchoalveolar lavage (BAL) fluid from smokers at risk of developing chronic obstructive pulmonary disease (COPD) and never smokers is described. COPD is currently the world's fourth leading cause of death and its prevalence is increasing. The leading cause of COPD is smoking and an estimated 600 million people in the world suffer from COPD which makes it the world's most co

Requirements engineering for market-driven software development entails special challenges. This paper presents results from an empirical study that investigates these challenges, taking a qualitative approach using interviews with fourteen employees at eight software companies and a focus group meeting with practitioners. The objective of the study is to increase the understanding of the area of

Site I of antigenic domain 2 (AD-2) on human cytomegalovirus glycoprotein B (gB) is poorly immunogenic in both man and mouse and knowledge about antibody repertoires reactive with this epitope is thus limited. Here we have characterized a phage display-derived repertoire of antibody fragments specific for this epitope in terms of antigen recognition, fine-specificity, and virus-neutralizing capaci

Popular Abstract in Swedish I denna avhandling analyseras unga mäns vålds- och offerupplevelser. Studien bygger på olika typer av material men det mest centrala underlaget består av samtalsintervjuer med unga män som har blivit utsatta för misshandel eller rån. Sätten på vilka de unga männen talar om sig själva, förövaren, våld och offerskap utgör utgångspunkten för analysen. Inom ramen för samtalIn this dissertation, young men's experiences of being victims of crime are analysed. Several kinds of material are considered in this study, but the primary data consist of informal, tape-recorded interviews with ten young men (17 to 21 year's old) who had been assaulted or mugged. Their accounts of their experiences are analysed using a number of constructionist, interactionist, and narrative pe

The RISING (Rare ISotope INvestigations at GSI) project constitutes a major pan-european initiative to study nuclear structure in exotic nuclei. A brief outline of the technical details specific to studies of isomeric decays following relativistic projectile fragmentation reactions is presented.

Context: Testis development is a tightly regulated process that requires an efficient and coordinated spatiotemporal action of many factors, and it has been shown that several genes involved in gonadal development exert a dosage effect. Chromosomal imbalances have been reported in several patients presenting with gonadal dysgenesis as part of severe dysmorphic phenotypes. Results: We screened for

A synthetic polymer selective for (S)-naproxen was prepared by molecular imprinting. 4-Vinylpyridine and ethylene glycol dimethacrylate were copolymerised in the presence of the template, (S)-naproxen. The template was extracted from the polymer, leaving specific recognition sites, complementary to the template. The polymer was utilized as a stationary phase in HPLC. Racemic naproxen was efficient

In this paper we investigate the structure and motion problem for calibrated one-dimensional projections of a two-dimensional environment. The theory of one-dimensional cameras are useful in several areas, e.g. within robotics, autonomous guided vehicles, projection of lines in ordinary vision and vision of vehicles undergoing so called planar motion. In a previous paper the structure and motion p