Sökresultat

Filtyp

Din sökning på "*" gav 531310 sökträffar

Critical Social Theory Approaches to European integration

Critical Social Theory (CST), in its broadest sense, is a transdisciplinary approach to the social sciences that applies critique to the status quo in order to emancipate humans and the planet from the negative consequences of modernity. The development of CST as a critical theoretical approach to European integration grew through the 1990s, with an increasing concern for understanding and challen

From space to specs : Requirements for 4MOST

4MOST,1 the 4m Multi-Object spectrographic Survey Telescope, is an upcoming optical, fiber-fed, MOS facility for the VISTA telescope at ESO's Cero Paranal Observatory (Chile). The preliminary design of 4MOST features 2,400 fibers split into a low-resolution (1,600 fibers, 390-900 nm, R > 5; 000) and a high-resolution channel (800 fibers, three arms, ∼20-25 nm coverage each, R > 18; 000) with an Ec

Age and metallicity gradients in the Galactic Bulge : A differential study using HST/WFPC2 observations

We test for age and metallicity gradients in the Galactic Bulge between the two low extinction windows Baade's window (l = 1°.1 b = -4°.8) and Sagittarius-I (l = 1°.3 b = -2°.7). We derive a metallicity difference of ≤ 0.2 dex between BW and SGR-I window. This corresponds to a metallicity gradient of 1.3 dex kpc-1. This steep gradient is reconcilable with the existence of a short scale length inne

Atomic data for the Gaia-ESO Survey

Context. We describe the atomic and molecular data that were used for the abundance analyses of FGK-type stars carried out within the Gaia-ESO Public Spectroscopic Survey in the years 2012 to 2019. The Gaia-ESO Survey is one among several current and future stellar spectroscopic surveys producing abundances for Milky-Way stars on an industrial scale. Aims. We present an unprecedented effort to cre

177Lu-PSMA-617 Therapy in Mice, with or without the Antioxidant α1-Microglobulin (A1M), Including Kidney Damage Assessment Using 99mTc-MAG3 Imaging

Anti-prostate specific membrane antigen (PSMA) radioligand therapy is promising but not curative in castration resistant prostate cancer. One way to broaden the therapeutic index could be to administer higher doses in combination with radioprotectors, since administered radioactivity is kept low today in order to avoid side-effects from a high absorbed dose to healthy tissue. Here, we investigated

Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation

Dopaminergic (DA) neurons derived from human pluripotent stem cells (hPSCs) represent a renewable and available source of cells useful for understanding development, developing disease models, and stem-cell therapies for Parkinson's disease (PD). To assess the utility of stem cell cultures as an in vitro model system of human DA neurogenesis, we performed high-throughput transcriptional profiling

Transnational Solidarity : Concept, Challenges and Opportunities

The book analyses the concept and conditions of transnational solidarity, its challenges and opportunities, drawing on diverse disciplines as Law, Political Science, Sociology, Philosophy, Psychology and History. In the contemporary world, we see two major opposing trends. The first involves nationalistic and populistic movements. Transnational solidarity has been under pressure for a decade becau

Toxicological effects of zinc oxide nanoparticle exposure: an in vitro comparison between dry aerosol air-liquid interface and submerged exposure systems

Engineered nanomaterials (ENMs) are increasingly produced and used today, but health risks due to their occupational airborne exposure are incompletely understood. Traditionally, nanoparticle (NP) toxicity is tested by introducing NPs to cells through suspension in the growth media, but this does not mimic respiratory exposures. Different methods to introduce aerosolized NPs to cells cultured at t

Symbols and Myths of European Union Transnational Solidarity

The chapter explores the symbols and myths of EU transnational solidarity through a threefold analysis of transnational solidarity within, across, and beyond the EU. Based on post-Cold War study of the EU in global politics over the past three decades, it compares and contrasts transnational solidarity from communitarian and cosmopolitan perspectives before advocating a cosmopolitical understandin

Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture

BACKGROUND: Germinal matrix intraventricular hemorrhage (GM-IVH) is associated with deposition of redox active cell-free hemoglobin (Hb), derived from hemorrhagic cerebrospinal fluid (CSF), in the cerebrum and cerebellum. In a recent study, using a preterm rabbit pup model of IVH, intraventricularly administered haptoglobin (Hp), a cell-free Hb scavenger, partially reversed the damaging effects ob

Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity : A Randomized Clinical Trial

Importance: Lack of arachidonic acid (AA) and docosahexaenoic acid (DHA) after extremely preterm birth may contribute to preterm morbidity, including retinopathy of prematurity (ROP).Objective: To determine whether enteral supplementation with fatty acids from birth to 40 weeks' postmenstrual age reduces ROP in extremely preterm infants.Design, Setting, and Participants: The Mega Donna Mega trial,