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The number of oocytes retrieved during IVF : A balance between efficacy and safety

STUDY QUESTION: What is the relationship between the number of oocytes collected in fresh IVF treatments and the likelihood of cumulative delivery rate (fresh and frozen) per oocyte aspiration, severe ovarian hyperstimulation syndrome (OHSS) and thromboembolic events? SUMMARY ANSWER: Cumulative delivery rate per aspiration increases up to 20 oocytes retrieved and then evens out while the incidence

Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

The transcription factor ZNF224 plays a key proapoptotic role in chronic myelogenous leukemia (CML), by modulating Wilms Tumor protein 1 (WT1) dependent apoptotic genes transcription. Recently, we demonstrated that Bcr-Abl signaling represses ZNF224 expression in Bcr-Abl positive CML cell lines and in CML patients. Interestingly, Imatinib and second-generation tyrosine kinase inhibitors specifical

Quality transformation of dissolved organic carbon during water transit through lakes : contrasting controls by photochemical and biological processes

Dissolved organic carbon (DOC) may be removed, transformed, or added during water transit through lakes, resulting in changes in DOC composition and pigmentation (color). However, the process-based understanding of these changes is incomplete, especially for headwater lakes. We hypothesized that because heterotrophic bacteria preferentially consume noncolored DOC, while photochemical processing re

The Concordant Space of Biomedical Science : How Individuals with Parkinson's Disease Synchronize themselves with Clinical Trials

Parkinson’s disease (PD) becomes more frequent as populations grow older in western countries. Levodopa exists as medication, but is connected with side-effects. In search for an alternative therapy, patients become agents in different ways. The role as participant in clinical trials, not least, is one of these possibilities for lay influence in scientific matters. In this presentation we ask how

Temporal trends and regional disparity in rheumatoid arthritis and gout hospitalizations in Sweden, 1998-2015

Hospitalization is an important component of rheumatoid arthritis (RA) and gout economic burden. This study aimed to assess temporal trends and regional disparities in RA and gout hospitalizations among people aged ≥ 20 years in Sweden during 1998-2015. Data on hospital admissions with a principal diagnosis of RA or gout were collected from the National Patient Register. Age-standardized hospitali

Only Connect : A passage from Modernism to Postmodernism

In Cultural Communication: Approaches to Modernity and Postmodernity (2014) I studied the evolution of the canon as a result of the aesthetical and ideological transformations during the 20th century. The elaboration of the canon comports distinctions in terms of the relationship between modernism and postmodernism. Jennifer Ashton insisted on the transformations suffered by the regime of texts. T