Sökresultat

Filtyp

Din sökning på "*" gav 536385 sökträffar

Early trauma responses and psychopathology. Setting up the stage.

Research on short- and long-term response to trauma has been expanding over the past twenty years and has found new urgency in recent national and international events. As our understanding of risk factors for who will be most severely affected by trauma expands, what we don't know about the interactions between vulnerabilities and risk factors, peritraumatic and posttraumatic factors, physiologic

Constraint-driven identification of application specific instructions in the DURASE system

This paper presents a new constraint-driven method for fast identification of computational patterns that is a part of DURASE system (Generic Environment for Design and Utilization of Reconfigurable Application-Specific Processors Extensions). The patterns identified by our system form a base for application specific instruction selection and processor extension generation. Our method identifies a

Subcellular distribution of spermidine/spermine N(1)-acetyltransferase

The subcellular distribution of the polyamine catabolic enzyme spermidine/spermine N(1)-acetyltransferase (SSAT) was studied in L56Br-C1 cells treated with 10muM N(1),N(11)-diethylnorspermine (DENSPM) for 24h. Cells were fractioned into three subcellular fractions. A particulate fraction containing the mitochondria was denoted as the mitochondrial fraction. After DENSPM treatment, an increase in S

MiniReview: Bioinformatic study of bile responses in Campylobacterales

Campylobacter, Helicobacter and Wolinella are genera of the order Campylobacterales, belonging to the class Epsilonproteobacteria. Their habitats are various niches in the gastrointestinal tract of higher animals, where they may come into contact with bile. Microorganisms in these environments require mechanisms of resistance to the surface-active amphipathic molecules with potent antimicrobial ac

Temporal correlation scheme for spectroscopic gas analysis using multimode diode lasers

The reliability of diode lasers used in spectroscopic applications is limited by their intrinsic multimode and mode-jump behavior when wavelength-tuned by current or temperature. We report on a scheme for gas analysis based on temporal correlation between absorption signals from an unknown external and a known reference gas concentration, simultaneously recorded when the diode laser wavelength is

Arthrodesis of the ankle secondary to replacement

One hundred total ankle arthroplasties were performed in our department between 1974 and 1994, and of these, 21 have been reoperated on with arthrodesis due to septic or nonseptic failures after 6 months to 15 years (median 40 months). Immobilization using a Hoffman external fixator was the dominating method. The total ankles were of six different designs. Sixteen of the 21 patients suffered from

One-year endometrial safety evaluation of a continuous combined transdermal matrix patch delivering low-dose estradiol-norethisterone acetate in postmenopausal women.

Objective: To evaluate the safety and endometrial protection of low-dose transdermal estradiol (E2)/norethisterone acetate (NETA) patches (Estalis 25/125) in terms of post-treatment incidence of endornetrial hyperplasia/cancer after 1 year of treatment in postmenopausal women with intact uteri. Methods: Patients were randomized to receive either transdermal E2/NETA (delivering daily doses of E2 25

Early neonatal brain injury in histologic chorioamnionitis

The relation between clinical or histologic chorioamnionitis and early neonatal adverse neurologic outcome was investigated (n = 483). Histologic, but not clinical, evidence of chorioamnionitis was found to be a significant predictor of periventricular echodensity (odds ratio, 2.4; 95% CI, 1.8-3.2), echolucency (3.3; 1.9-5.6), ventriculomegaly (2.7; 1.8-4.2), intraventricular hemorrhage > or =3 (3

mRNAs of tyrosine hydroxylase and dopa decarboxylase but not of GD2 synthase are specific for neuroblastoma minimal disease and predicts outcome for children with high-risk disease when measured at diagnosis

Several transcripts have been claimed to be clinically valuable for detecting minimal disease in neuroblastoma, but they have not been prospectively compared in a standardized manner. Tyrosine hydroxylase (TH), dopa decarboxylase (DDC) and GD2 synthase (GD2S) mRNAs were analyzed in 554 blood (PB) and bone marrow (BM) samples from 58 children with neuroblastoma. Samples from 44 children with other

Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays.

The driving force behind oncoproteomics is to identify biomarker signatures associated with a particular malignancy. Here, we have for the first time used large-scale recombinant scFv antibody microarrays in an attempt to classify metastatic breast cancer versus healthy controls, based on differential protein expression profiling of whole serum samples. Using this multiplexed and miniaturised assa

Peasants and entrepreneurship in the nineteenth-century agricultural transformation of Sweden

In post-World War II agricultural research, a new perspective on "peasant society" developed. This approach is still vigorous today and implies that peasant society defined by subsistence production, the safety-first principle, and a stable village system with moral obligations-leads to conservative behavior toward change. It also assumes that only external forces can tear down the system and forc

Pulsed field gradient NMR study of poly(ethylene glycol) diffusion in whey protein solutions and gels

PEG self-diffusion coefficients of poly(ethylene glycol)s (PEGs) (1080, 8500, and 82 250 g/mol) were measured by PFG-NMR spectroscopy in whey protein solutions and gels in relation to whey protein concentration effects (from 6.49 to 40.45 g/100 g) and whey protein heat denaturation effects (30 min at 70 degrees C). A strong dependency of diffusion on probe size was observed in both whey protein so

The happy obese child

OBJECTIVE: Firstly, is the negative psychological effect of obesity also present in the whole population of obese and overweight children? Secondly, what tools could be recommended to measure the psychological effects of obesity? DESIGN: Review. METHODS: Quality of life or self-esteem is often used in evaluating the psychological effects of obesity. Test instruments used have been instruments for

Influence of treatment with diethylstilbestrol for carcinoma of prostate on platelet aggregation and plasma lipoproteins

Treatment of prostatic carcinoma with estrogens is accompanied by an increased risk for thromboembolic and cardiovascular complications. The underlying mechanisms are still unknown. Patients treated with diethylstilbestrol (DES) were compared with patients given no estrogen treatment regarding factors (platelet aggregation in vitro and plasma lipoproteins) that have been suggested to contribute to

Transient post-mating inhibition of behavioural and central nervous responses to sex pheromone in an insect

Mating is costly for both male and female insects and should therefore only occur if it is likely to be successful. Within one scotophase, which is the dark period of the light cycle, male moths can only produce one single spermatophore, which is transferred to the female during mating. Remating within the same scotophase would thus be unsuccessful. We tested the hypothesis that newly mated males