Regulation of ornithine decarboxylase expression
It has become increasingly obvious during the last two decades that a multitude of cellular processes are highly dependent on adequate levels of polyamines (1–6). Too high concentrations of the polyamines are toxic to the cell and may induce cell death or apoptosis (7). On the other hand, too low concentrations may negatively affect anabolic events, such as the synthesis of DNA, RNA, and protein,