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Individualized PID Control of Depth of Anesthesia Based on Patient Model Identification During the Induction Phase of Anesthesia

This paper proposes a closed-loop propofol admission strategy for depth of hypnosis control in anesthesia. A population-based, robustly tuned controller brings the patient to a desired level of hypnosis. The novelty lies in individualizing the controller once a stable level of hypnosis is reached. This is based on the identified patient parameters and enhances suppression of output disturbances, r

Nationalmuseer som tidsspegel. 2000-talets forntider i Danmark och Sverige

This is a study of two recently opened exhibitions on prehistoric times at the national museums of Denmark and Sweden respectively. It is argued that the contents of the exhibitions explicitly mirror the present discussions and political climates in each country. As a means of taking part of present times in these versions of the past, the exhibitions are extremely well suited for the purpose. In

Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study

Background: This phase II study evaluated the safety and activity of ipilimumab, a fully human mAb that blocks cytotoxic T-lymphocyte antigen-4, in patients with advanced melanoma. Patients and methods: Patients with previously treated, unresectable stage III/stage IV melanoma received 10 mg/kg ipilimumab every 3 weeks for four cycles (induction) followed by maintenance therapy every 3 months. The

The black box of everyday life : entanglements of stuff, affects and activities

Ethnologists like to think of themselves as masters of the study of the everyday, but we still know surprising little how this mundane machinery works. Everyday life remains something of a black box, our understanding is still piecemeal and fragmented. This paper explores cohabitation and circulation of objects, affects and activities in the home - seen as a workshop where raw materials, raw feeli

Strong Inbreeding Depression in Two Scandinavian Populations of the Self-Incompatible Perennial Herb Arabidopsis Lyrata

Inbreeding depression is a key factor influencing mating system evolution in plants, but current understanding of its relationship with selfing rate is limited by a sampling bias with few estimates for self-incompatible species. We quantified inbreeding depression () over two growing seasons in two populations of the self-incompatible perennial herb Arabidopsis lyrata ssp. petraea in Scandinavia.

Thrombosis in Children

Aims: The general objective was to further elucidate thromboembolic disease in children and thereby help improve the care of these patients. More specific aims were as follows: to determine what children are affected by thrombosis; to discern any gender or age differences related to thrombosis; to identify prothrombotic risk factors; to ascertain whether autoantibodies against coagulation proteins

Crypt fission contributes to postnatal epithelial growth of the small intestine in pigs

Studies on growth of the small intestine have mostly concentrated on crypt hyperplasia rather than crypt fission (CF). The process of crypt bifurcation has been identified in rodents and humans but not in swine. The main aims of this study were: 1) to investigate quantitatively crypt fission in the small intestine mucosa of pigs of different age-groups and 2) to assess the effect of colostrum and

Impersonal null-subjects in Icelandic and elsewhere

We study the properties of impersonal null-subjects, in particular in Icelandic, exploring the idea that such elements are constructed in syntax (rather than being lexical pronouns deleted in PF). In addition, we discuss the cross-linguistic distribution of impersonal null-subjects.

Relative Sources of European Regional Productivity Convergence: A Bootstrap Frontier Approach

Enflo K. and Hjertstrand P. Relative sources of European regional productivity convergence: a bootstrap frontier approach, Regional Studies. This paper addresses the issue of Western European regional productivity growth and convergence by means of data envelopment analysis (DEA), decomposing labour productivity into efficiency change, technical change and capital accumulation. The decomposition s

Search for the Standard Model Higgs boson in the H -> WW(*()) -> lvlv decay mode with 4.7 fb(-1) of ATLAS data at root s=7 TeV

A search for the Standard Model Higgs boson in the H -> WW(*()) -> lvlv (l = e.mu) decay mode is presented. The search is performed using proton-proton collision data corresponding to an integrated luminosity of 4.7 fb(-1) at a centre-of-mass energy of 7 TeV collected during 2011 with the ATLAS detector at the Large Hadron Collider. No significant excess of events over the expected background is o

Off-line Foveated Compression and Scene Perception: An Eye-Tracking Approach

With the continued growth of digital services offering storage and communication of pictorial information, the need to efficiently represent this information has become increasingly important, both from an information theoretic and a perceptual point of view. There has been a recent interest to design systems for efficient representation and compression of image and video data that take the featu

Soil surface CO2 efflux measurements in Norway spruce forests: Comparison between four different sites across Europe - from boreal to alpine forest

Extensive measurements of soil surface (including vegetation cover) CO2 efflux were carried out on 80 positions at four different forest sites (Sweden, Germany, Czech Republic and Italy) using a closed dynamic chamber technique. The period of measurement was 4-5 consecutive days per site. Two approaches were used to analyze the measured data, the Q(10) parameter and the Arrhenius relationship. Bas

A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET.

Ion channels and ion fluxes control many aspects of tissue homeostasis. During oncogenic transformation, critical ion channel functions may be perturbed but conserved tumor specific ion fluxes remain to be defined. Here we used the tumoricidal protein-lipid complex HAMLET as a probe to identify ion fluxes involved in tumor cell death. We show that HAMLET activates a non-selective cation current, w