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Disease-modifying therapies (DMTs) for multiple sclerosis (MS) can increase the risk of hepatitis B virus (HBV) reactivation (HBr), particularly with agents like ocrelizumab and alemtuzumab. However, studies in MS patients treated with DMTs indicate significantly lower reactivation rates compared to those with hematologic malignancies. This review discusses strategies for managing HBV in MS patien

Objectives: Iron deficiency anemia (IDA) is a common extraintestinal manifestation of inflammatory bowel disease (IBD), driven by impaired iron absorption, inflammation of intestinal mucosa and blood loss due to intestinal bleeding. Exogenous iron is indicated to correct iron deficiency, with intravenous iron preferred in patients with malabsorption or intolerance of oral iron, active bleeding, sy

This study investigates whether Developmental Language Disorder (DLD) is a specific language impairment or a domain-general disorder, thereby addressing the broader question of whether language processing is distinct from or comparable to cognitive processing in other domains. Specifically, we investigate semantic processing in verbal and pictorial domains among 9–12-year-old children with DLD in

Despite decades of research on the emergence of human speech capacities, an integrative account consistent with hominin evolution remains lacking. We review paleoanthropological and archaeological findings in search of a timeline for the emergence of modern human articulatory morphological features. Our synthesis shows that several behavioral innovations coincide with morphological changes to the

Background and Purpose: Absence from work due to illness is common in many western countries and has many negative consequences for both the individual and society. Since 2020 Swedish healthcare regions are required to provide resources to coordinate the rehabilitation process, a complex system involving medical as well as work-related parties, where both the physician and the rehabilitation coord

Introduction: Inflammatory diseases have been associated with increased risk of venous thromboembolism (VTE). However, data on VTE is lacking in large population-based cohorts of microscopic colitis (MC). Methods: This study included all Swedish adults with incident MC without prior VTE (1990-2017; n=12,489; follow-up until 2021). MC and subtypes (collagenous colitis and lymphocytic colitis) were

To what extent do the most powerful political office-holders engage with extra-parliamentary representatives from the most marginalised groups? To what extent and how are these relationships intersectional? In order to answer these questions, this article offers a novel analysis of over 78,000 UK government ministerial meetings and 293 equalities organisations. The findings show that white male mi

Open access editors replying questions about being part of open access journals and its challenges. This was part of the issue titled 'OPEN' of the Journal of Peer Production (issue 13)

In light of the recent Swedish elections where Sverigedemokratarna received 18% of the vote. Since the Swedish Democrats talk so much about culture, we anthropologists need to take a more nuanced position on how the issue of culture and immigrants 'fitting in' to Swedish society is discussed.

Bridges serve as vital links within transportation networks, fostering societal connectivity and economic growth. Italy’s diverse terrain, encompassing mountains, hillsides, and coastal regions, underscores the importance of bridge infrastructure. Following notable bridge collapses in recent years, understanding their causes and enhancing safety measures has become paramount. This study presents a

Many algorithms in computer graphics make use of acceleration structures such as Bounding Volume Hierarchies (BVHs) to speed up performance critical tasks, such as collision detection or ray-tracing. However, while the typical algorithms for constructing BVHs are relatively simple, actually implementing them for performance critical systems is still challenging. Further, to construct them as quick

Introduction: Antibodies targeting the blood-stage of Plasmodium falciparum play a critical role in naturally acquired immunity to malaria by limiting blood-stage parasitemia. One mode of action of antibodies is the direct inhibition of merozoite invasion of erythrocytes through targeting invasion ligands. However, evasion of inhibitory antibodies may be mediated in P. falciparum by switching betw

Introduction: Impulse control and related behavioral disorders (ICBDs) commonly complicate Parkinson’s disease (PD) course. The ICBDs spectrum encompasses two groups of conditions, with distinct pathophysiology: proper ‘impulse control disorders (ICDs)’ (e.g. gambling) and the ‘ICDs related disorders (ICDs-RD)’ (e.g. punding). Behavioral disturbances are associated with dopamine replacement therap

Background: The optimal timing of anticoagulation for patients with acute ischaemic stoke with atrial fibrillation is uncertain. We investigated the efficacy and safety of early compared with delayed initiation of direct oral anticoagulants (DOACs) in patients with acute ischaemic stroke associated with atrial fibrillation. Methods: We performed a multicentre, open-label, blinded-endpoint, paralle