LMO2, a member of the LIM-only protein family, is essential for the regulation of hematopoietic stem cells and formation of erythroid cells. It is found in a transcriptional complex comprising LMO2, TAL1, E47, GATA-1, and LDB1 which regulates erythroid genes. While TAL1 has been shown to induce erythroid differentiation, LMO2 appears to suppress fetal erythropoiesis. In addition to LMO2, the close

Founded on recent empirical experiences and results from a Housing Adaptation Project accomplished in a Swedish municipality, this paper aims to elucidate and problematize challenges inherent in the process of developing research-based strategies for housing adaptation (HA) evaluations feasible for municipality contexts. In this paper, theory and conceptual definitions of client-level outcomes rel

OBJECTIVE.: Finding of venous congestion at histopathological examination of placenta indicates the importance of abnormal placenta-maternal venous return. The present descriptive study investigates the possibility of recording Doppler flow signals from maternal uterine veins. MATERIAL AND METHODS.: Transabdominal Doppler ultrasound examinations of uterine veins on both sides of uterus were perfor

Over the last couple of years, international lawyers have hotly debated the correct way to apply Article 31, paragraph 3(c) of the 1969 Vienna Convention on the Law of Treaties. Discussions have focused on the meaning of ‘the parties’. Traditionally this expression has always been interpreted in the stricter sense of all parties to the interpreted treaty. Voices are now raised suggesting a broader

Objective. In the European Association of Urology guidelines on prostate cancer an extended pelvic lymphadenectomy (ePLND) is now recommended, instead of a dissection limited to the obturator fossae (lPLND). This recommendation relies on studies reporting that metastatic disease is identified twice as often with ePLND as with lPLND, with only moderately increased complications. However, these stud

An HbA1c threshold of ≥42 mmol/mol has been proposed to diagnose prediabetes. The sensitivity, specificity and positive predictive value of the proposed threshold for detection of individuals with prediabetes was examined in a study of 573 randomly selected individuals from Vara and Skövde. In addition, the utility of the FINDRISC questionnaire and of a fasting glucose test in combination with thr

AR-C117977, a monocarboxylate transporter inhibitor, reduces immune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. To evaluate the immunosuppressive limitations of AR-C117977, this study was performed in nonvascularized transplant models noted for their refractive response to standard immunosuppressive agents. Rat skin was transplanted f

Interaction with robot systems for specification of manufacturing tasks and motions needs to be simple, to enable wide-spread use of robots in SMEs. In the best case, existing practices from manual work could be used, to smoothly let current employees start using robot technology as a natural part of their work. Our aim is to simplify the robot programming task by allowing the user to simply make

En ansökan om betalningsföreläggande avvisas eller avskrivs för att gäldenären inte kan delges. Borgenären ansöker om stämning avseende samma sak. En omtvistad fråga — som rör förenklade tvistemål och tolkningen av 18 kap. 8 a § sjätte stycket rättegångsbalken — är om borgenären i tingsrättsförfarandet kan få ersättning för kostnaden hos Kronofogdemyndigheten. I denna artikel argumenteras för att

A collection of 18 articles on new perspectives of the historical archaeology from Lund.

Guidance of eye-movements in image viewing is believed to be controlled by stimulus driven factors as well as viewer dependent higher level factors such as task and memory. It is currently debated to what proportions these factors contribute to gaze guidance, and also how they vary over time after image onset. Overall, the unanimity regarding these issues is surprisingly low and there are results