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This thesis investigates several aspects on gastroesophageal reflux disease (GERD) and associated complications as Barrett’s esophagus and esophageal adenocarcinoma. I. To clarify the natural course of GERD, a pH-metry verified cohort was re-evaluated after 20 years. The course of GERD may well be progressive. A statement based on the evidence that reflux induced complications as esophagitis and
When a child is diagnosed with diabetes, the symptoms may be in its most severe form with ketoacidosis, to mild symptoms of diabetes, detected incidentally. Moderate and severe symptoms of diabetes presentation require infusion therapy and thereby necessitate hospitalisation for the first few days. The initial management is largely a preparation for family members to help them gain the practical u
Popular Abstract in English This thesis is concerned with the efficient generation of ultra-short light pulses, far beyond the visible spectral range. Such light pulses can reach durations below 100 attoseconds, where one attosecond is one billionth of a billionth of a second. Why do we want to generate such extreme light pulses? Our knowledge of basic processes in physics and chemistry is to aHigh-order harmonic generation (HHG) provides the basis for attosecond light sources delivering coherent pulses in the extreme ultraviolet spectral region. Such light sources are employed for a variety of applications within imaging, attosecond spectroscopy, and high-precision frequency metrology. However, the rather low efficiency of the HHG process, which implies a limited pulse energy and repet
Acid-base status in umbilical cord blood is an objective measure of the fetus’ exposure to and ability to handle hypoxia. The objective of this thesis was to clarify some of the methodological pitfalls in interpreting umbilical cord blood gases and lactate values at birth. Study I pinpoints the methodological confounding in calculating base deficit (BD) with algorithms used in different brands of
Summary This master thesis evaluates the benefits of using multi-echelon control instead of single-echelon control of a multi-echelon inventory system. The multi-echelon inventory system studied in this thesis is a one-warehousemultiple- retailer inventory system. Multi-echelon inventory control is defined as a method to optimize the inventory system by taking the interdependencies between differe
Although development of electrical vehicles seems to go forward, they are still best suitable for short range transportation, and are dependent of generation of clean electricity to be environmental friendly. The fuel cell has issues to be solved, for example low efficiency at loading, and also problem of generating and storing the hydrogen fuel in an efficient way. Recent years the hybrid vehicle
System Thinking is the mindset of defining and confining a problem and its symptoms as well as a method for communicating system understanding. System Analysis is taking that problem apart to understand its causalities and structural arrangement. System Dynamics is the use of the results of System Analysis in order to reconstruct the system of causalities. Modelling is used for understanding comp
Aim: The overall aim of this thesis was to illuminate older persons' experience of becoming in need of public home help and their family members' experience of this situation. Further, the aim was to illuminate experiences of participation in the needs assessment process of older people and influence on decisions about public home help from the perspective of older needs-assessed persons, their fa
Popular Abstract in English Popular Science Abstract In our daily routines, we use products and come across applications that involve mixtures of polymers and small amphiphilic molecules in water, for example detergents, pharmaceutics, foodstuffs, shampoos and paints. Polymers are very large molecules formed by smaller units that are repeated and connected. Amphiphilic molecules contain both one pThe research described in this thesis aims to understand the interactions between cationic poly(amidoamine) (PAMAM) dendrimers and small oppositely charged amphiphiles at the solid-liquid and air-liquid interfaces in relation to the bulk solution behavior. There is high interest in PAMAM dendrimers because they are well-defined polymers with a hierarchical architecture which makes them promising m
The aim was to investigate the presence of everyday problems in men with prostate cancer, their relation to health-related quality of life, HRQOL, and sense of coherence, SOC, and to compare with men with benign prostatic hyperplasia, BPH, and a sample from the general population. The aim also was to investigate what nursing care needs there were in men with prostate cancer and how these were met
Maten handlar om vår fysiska överlevnad, men maten har också viktiga sociala funktioner i familjen/hushållet. I vår undersökningen ser vi hur konsumtionen ser ut i familjerna; konsumtionen blir en utbytesprocess mellan barn och föräldrar, mellan flickor och pojkar. Rapporten baserar sig på en empirisk studie med gruppintervjuer med 7-8 åriga barn från fyra nordiska länder, Sverige, Norge, Danmark Food is essential for our survival, but food has important social functions in the family/household as well. In our study we examine how consumption looks in the family; consumption becomes a process of exchange between children and parents, and between girls and boys. The report is based on an empirical study consisting of group interviews with 7-8 year old children from four Nordic countries: Sw
Svår fetma är ett svårbehandlat tillstånd och hittills har fetmakirurgi visat sig vara den metod som ger den största och mest beständiga viktminskningen över längre tid. Fetmakirurgi har tidigare endast erbjudits vuxna både i Sverige och i andra länder. Under senare år har fetmakirurgi börjat prövas som ett behandlingsalternativ till ungdomar med svår fetma där annan behandling inte har gett tillr
There is a strong relationship between regional sediment transport and the local processes at tidal inlets and around coastal structures. Many coastal projects require quantitative understanding of these processes and the interactions between them. Regional sediment transport and shoreline evolution models that fully include important coastal processes at local scale are lacking at present. The ov
Abstract: Breast cancers are heterogeneous tumours. Prognostic markers are needed to better profile the patient´s risk, and predictive markers to indicate the expected benefit of systemic treatment. Using gene expression analyses, breast tumours can be divided into intrinsic subtypes. Immunohistochemical (IHC) markers (oestrogen and progesterone receptors (ER and PR), human epidermal growth facto
Importance: There is currently no consensus as to which biomarkers best predict longitudinal tau accumulation at different clinical stages of Alzheimer disease (AD). Objective: To describe longitudinal [18F]RO948 tau positron emission tomography (PET) findings across the clinical continuum of AD and determine which biomarker combinations showed the strongest associations with longitudinal tau PET
Avhandlingens titel "Kustnära yrkesfiske i förändring. Från mångsysslare till entreprenör" hänvisar till de förändringar som fiskenäringen har genomgått under flera decennier. Fiskenäringen har rationaliserats samtidigt som besöksnäringen vid kusten expanderat. Antalet yrkesfiskare i kustnära yrkesfiske har därför minskat och näringen måste förhålla sig till nya informella krav och förväntningar pIn this dissertation inshore commercial fisheries are being studied from a cultural analytical perspective with a focus on service production and hospitality. The dissertation title, ”Inshore commercial fisheries in change. From pluri-activity to entrepreneurship”, refers to the multiple kinds of change that the fishing industry has undergone for a long period in time. They include rationalization
Background: Cluster analyses have proposed different diabetes phenotypes using age, BMI, glycaemia, homoeostasis model estimates, and islet autoantibodies. We tested whether comprehensive phenotyping validates and further characterises these clusters at diagnosis and whether relevant diabetes-related complications differ among these clusters, during 5-years of follow-up. Methods: Patients with new
Cities are seen as one of the leading forces in making our societies sustainable and resource efficient. The latest trends of sharing homes, cars, bikes, tools and other goods are fast entering our urban lives. The sharing economy is a consumption-production mode in a city, in which value is generated through transactions between peers or organisations that offer access to their idling or underuti
