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Background: Despite decades of engineering efforts, recombinant Saccharomyces cerevisiae are still less efficient at converting d-xylose sugar to ethanol compared to the preferred sugar d-glucose. Using GFP-based biosensors reporting for the three main sugar sensing routes, we recently demonstrated that the sensing response to high concentrations of d-xylose is similar to the response seen on low

Kultfilmsevenemang som Den Dåliga Filmfestivalen (Göteborg, 2019 och 2023-2025) och B-Filmsklubben (Malmö) erbjuder unika atmosfärer för publiken som besöker dem. I Malmö och Göteborg anordnar biograferna regelbundet festivaler och fristående visningar av kultfilmer som band andra The Room, Birdemic, och Miami Connection. Kännetecknande för dessa upplevelser är den översvallande atmosfär som skapa

This dissertation investigates the development of the main Danish modal particles jo, sgu, skam, nu, da, vel, nokand vist. In Modern Danish, these particles express contextualization instructions, that is, they express how theutterance relates to the interactive context. In addition to this common content core, they also share severalexpression features: they cannot be placed in the pre-field, the

PURPOSE: Early identification of the underlying cause of intracerebral hemorrhage (ICH) is important for treatment and prognosis. This study aims to investigate the association of hematoma volume and other clinical parameters on the distribution of cerebral amyloid angiopathy (CAA) probability according to the simplified Edinburgh CT criteria in a large, unselected intracerebral hemorrhage (ICH) p

Aims: Men are more likely to suffer a myocardial infarction than women, but population-based studies on sex differences in imaging-detected atherosclerosis are lacking. The aims were to assess sex differences in the prevalence of imaging-detected coronary and carotid atherosclerosis, as well as multivariable adjusted associations between sex and atherosclerosis. Methods and results: Participants a

BACKGROUND: Currently, there are no therapies targeting specific pathogenic pathways in myocarditis. IL (interleukin)-1 blockade has shown promise in preclinical studies and case reports. We hypothesized that blockade of IL1RAP (IL-1 receptor accessory protein), a shared subunit of the IL-1, IL-33, and IL-36 receptors, could be more efficient than IL-1 blockade alone. METHODS: We induced coxsackie

Introduction: The role of the complement inhibitory proteins CD46 and CD59 in the immune response to an acute coronary syndrome (ACS) is unknown. We investigated the relationships between the shedding of CD46 and CD59 into the circulation, reflected by plasma levels of soluble CD46 and CD59, and the risk for post-ACS complications. Methods: We measured plasma sCD46 and sCD59 in a cohort of 546 ACS

Background: High gluten and low dietary fiber in pregnancy intake is associated with an increased risk of celiac disease (CeD) in the child. Early life higher dietary quality is suggested to reduce the subsequent risk of CeD. Objectives: The aim was to investigate associations of pregnancy dietary quality and diversity with child risk of CeD. Methods: In The Norwegian Mother, Father and Child Coho

Ojämlikhet, i termer av hur resurser fördelas mellan olika kategorier av människor, är ett genomgripande samhällsfenomen. Den svenska arbetsmarknaden är inget undantag och uppvisar en betydande grad av klassad, etnifierad och könad ojämlikhet när det gäller tillgång till kontroll och makt över produktionsförhållanden. Denna avhandling syftar till att bidra med kunskap om hur och varför ojämlikhets

Aims/hypothesis: The temporal suppression of insulin clearance after glucose ingestion is a key determinant of glucose tolerance for people without type 2 diabetes. Whether similar adaptations are observed after the ingestion of a mixed-macronutrient meal is unclear. Methods: In a secondary analysis of data derived from two randomised, controlled trials, we studied the temporal responses of insuli

Environmental loads, such as wind and river flow, play an essential role in the structural design and structural assessment of long-span bridges. Climate change and extreme climatic events are threats to the reliability and safety of the transport network. This has led to a growing demand for digital twin models to investigate the resilience of bridges under extreme climate conditions. Kalix bridg

BACKGROUND: Few studies have explored the association between DNA methylation and physical activity. The aim of this study was to evaluate the association of objectively measured hours of sedentary behavior (SB) and moderate physical activity (MPA) with DNA methylation. We further aimed to explore the association between SB or MPA related CpG sites and cardiometabolic traits, gene expression, and

Introduction: Allogeneic stem cell transplantation (allo-HCT) involves a long trajectory with high risk of complications. In person-centred care (PCC), patients’ needs, resources and the care relationship are central to the care process. Healthcare professionals’ (HCPs) ratings of PCC have not previously been investigated in this context. Objectives: The aim of this study was to investigate health

Background: Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking. Objectives: This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting. Methods: We assessed the 5-year outcomes of all patients undergoing IFR or FFR assessment be

Background: Lower limb deep vein thrombosis (DVT) is common in emergency departments (EDs) and can be fatal if left untreated due to the risk of progression to pulmonary embolism (PE). In Scandinavia, DVT diagnosis typically relies on ultrasound performed outside the ED in the diagnostic departments. However, international guidelines now recommend combining limited/proximal compression ultrasound

BACKGROUND: Insufficient knowledge among assistant nurses (ANs) in nursing homes (NHs) on medicines and drug-related problems (DRPs) in older people causes difficulties in acknowledging the side effects of medications, which can be harmful to the individual and endangers patient safety. The aim of this study was to explore the ANs' thoughts on their professional role in preventing DRPs in NH resid

Background: Orthodontic treatment need has commonly been assessed using treatment need indices during clinical examinations or using photographs in combination with plaster casts. Recently, the use of intraoral photographs alone to screen malocclusions has increased. Objective: This study aimed to validate intraoral photographs for the assessment of orthodontic treatment need. Materials and Method

The paper is a critical analysis of the present archaeological evidence for the pioneer settlement in Scandinavia. Based on a database of lithic blade technology from 62 sites dated to the Early Mesolithic, the authors evaluate the evidence for an East European origin of the Middle Mesolithic culture. Using lithic technology as a proxy for cultural traditions it is argued that the evidence speaks This paper takes as a point of departure the analysis of complex blade industries as a proxy for cultural practices, socially learned and transmitted habits within a human network. Our main objective is to study how traditions and/or habits are protected and reproduced or changed as groups of people are confronted with changed natural and/or social environments. Our case study is the hypothesized