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Background Self-harm is a prevalent health concern among youths, with significant psychosocial impacts on both youths and their parents. The aim of this study is to describe the impact of offspring self-harm on parental work absence. Methods This cohort study included 176 472 mothers and 161833 fathers of 17 726 youths with a first self-harm diagnosis between the years of 2006 and 2016 and 177 260

Syftet med detta arbete är att undersöka om rullande bärighetsmätningar RWD är ett alternativ till fallviktsmätningar FWD i arbetet kring vägbärighet i vägprojekt. Bärighet beskrivs av Trafikverket som ” Den högsta last, enstaka eller ackumulerad, som kan accepteras med hänsyn till uppkomst av sprickor eller deformationer”. Det vill säga hur tunga fordon en väg eller en bro kan belastas med s

It is predicted that continentality, a climate parameter representative of a region’s annual temperature and precipitation range, will undergo significant changes in the future. The lack of past continentality reconstructions makes it impossible to decipher any long-term patterns of continentality changes. Here, we investigate the extent to which continentality influences modern chironomid assembl

Background: Despite considerable interest in the consequences of benzodiazepine and benzodiazepine-related Z-drug (BZDR) use, little is known about whether and how initiation of BZDR treatment relates to the development of alcohol- and drug-related problems. Aims: This study aimed to examine the association of incident BZDR dispensing with subsequent alcohol- and drug-related problems. Methods: Th

Background and aims: Animal studies have suggested that high salt intake might increase the risk of metabolic dysfunction-associated steatotic liver disease (MASLD), but results from populations are mixed, in part due to inadequate salt intake measurement. Salty taste preference is the primary factor leading to salt choice and can reflect habitual salt intake. However, no study has investigated t

Single-cell and single-nuclei RNA-sequencing (scRNA-seq and snRNA-seq) analyze cell-specific transcriptomes. However, only snRNA-seq applies to frozen biobanked samples. For human pancreatic islets, marker genes and reference-based cell type annotation methods are mainly from scRNA-seq datasets and may not be suitable for snRNA-seq. We compared human islet scRNA-seq and snRNA-seq data from the sam

Introduction: Food systems strongly influence both human and planetary health. Unhealthy diets aremajor risk factors for chronic disease and mortality, while food production contributes substantially togreenhouse gas emissions (GHGE), and other negative environmental impacts. Adopting moresustainable dietary patterns, such as the EAT-Lancet diet, has been proposed as part of the solution, butuncer

Introduction: Target volume delineation is crucial in breast cancer radiotherapy planning but involves significant interobserver variability. Deep learning (DL) models may reduce this variability, saving time and costs. However, current DL-models do not consider clinical data, such as tumor location and patient comorbidity, to adjust the target and reduce dose to organs at risk (OAR). This study c

Background Low-grade systemic inflammation is linked to abnormal spirometry. Impulse oscillometry (IOS) is sensitive in detecting peripheral airway dysfunction, but inflammation in relation to IOS is poorly studied. The objectives of the present study were to analyse associations between C-reactive protein (CRP), blood eosinophils (B-Eos), blood neutrophils (B-Neu), blood lymphocytes (B-Lym), bloo

Background: Mental health professionals often differ in their explanatory models of mental distress, which may influence their attitudes toward individuals experiencing such conditions. Stigmatizing attitudes among providers can adversely affect therapeutic relationships, service quality, and recovery outcomes. Aims: This study investigates the attributional frameworks—biological, cognitive-behavi

Extreme climate events, such as heatwaves, are predicted to increase in frequency, intensity, and duration in the near future. Subarctic and boreal climate zones are expected to be especially negatively impacted, as recent shifts in temperature regimes are already particularly strong compared with more southern biomes. While many studies have focused on gradual warming and on both acute and chroni

Background: Chronic subdural hematoma (CSDH) is a rapidly growing neurosurgical condition, driven primarily by an aging population and the increasing use of antithrombotic medications. Approximately 25% of CSDH patients are on anticoagulants due to atrial fibrillation (AF). The postoperative management of these patients presents a significant clinical challenge, as clinicians must balance the risk

De senaste åren har präglats av en repressiv kriminalpolitik vilket kommit till uttryck i reformer som påverkat särbehandlingen av barn och unga la-göverträdare. I juli 2023 tillsattes utredningen SOU 2025:11 Straffbarhets-åldern med uppdrag att överväga och föreslå en sänkning av straffbarhets-åldern. Utredningens arbete resulterade till en sänkning av straffbarhetsål-dern till 14 år vid allvarli

Syftet med uppsatsen är att beskriva och analysera hur regelverket kring penningtvätt samspelar med dataskyddsrätten, särskilt i fråga om hanteringen av kunduppgifter som används för att uppfylla bankers krav på kundkännedom. Uppsatsen behandlar dels vilka skyldigheter bankerna har enligt penningtvättsregler, dels vilka krav EU:s dataskyddsbestämmelser ställer på bankernas behandling av personuppgThe purpose of this thesis is to describe and analyse how Anti-Money Laundering regulations interact with Data protection law, particularly regarding the handling of customer data used to fulfil banks’ customer due diligence requirements. The thesis examines both the obligations imposed on banks under Anti-Money Laundering rules and the requirements set by the EU’s data protection framework for th

BACKGROUND: Recent research using a data-driven cluster approach has identified five discordant subclassifying body mass index (BMI) subgroups, characterized by cardiometabolic biomarkers deviated from those predicted by BMI.OBJECTIVE: This study aimed to investigate the associations of these subgroups with risks of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver-related

BACKGROUND: Peptic gastroduodenal stenosis is a rare but disabling condition causing gastric outlet obstruction. This study aimed to evaluate endoscopic balloon dilation in terms of treatment effectiveness, durability, and identify potential early predictors of unsatisfactory outcomes.METHODS: We conducted a retrospective cohort study of patients who underwent endoscopic balloon dilation for sympt

Den 1 juli 2018 ändrades våldtäktsbrottet i Sverige, så att det inte längre krävdes att den tilltalade använt våld, hot eller utnyttjande för att få målsä-gande att delta i samlaget. I stället drogs gränsen för våldtäkt vid att delta-gandet inte varit frivilligt. Frivillighet är i detta sammanhang inte samma sak som målsägandens vilja. I stället handlar det om hur offret har visat den tilltalade v