Filtyp
Regeringen lade under hösten 2020 fram ett förslag om att utöka tillämpningsområdet för hemliga tvångsmedel genom att införa en straffvärdeventil som tar sikte på flerfaldig brottslighet. Förslaget motiveras mot bakgrund av att de brottsutredande myndigheterna är i behov av effektiva utredningsåtgärder för att kunna utreda mindre allvarliga brott som sker på ett systematiskt sätt. Införandet av en
Syftet med uppsatsen har varit att undersöka i vilken utsträckning unga personer som utsätts för våld av en partner med vilken de varken är gifta eller sambo omfattas av närståenderekvisitet i brottet grov fridskränkning och att analysera hur ungas utsatthet vid våld i ungas partnerrelationer bedöms vid tillämpningen av detta brott. Med utgångspunkt i förarbeten och prejudikat från Högsta domstoleThe purpose of this thesis has been to investigate to what extent young people who are subjected to violence by a partner whom they neither are married to nor cohabiting with, are considered to have a close relationship to the perpetrator according to the offence of gross violation of integrity, and to analyze how the vulnerability of young people in violent youth relationships is being assessed i
Skyddet för immateriella rättigheter prioriteras högt av lagstiftaren eftersom det anses vara viktigt för samhällsutvecklingen. Den illegala fildelningen på nätet har medfört nya utmaningar för det upphovsrättsliga skyddet, särskilt eftersom identifiering av intrångsgörare blir allt svårare med dagens teknik. Mot bakgrund av detta infördes en möjlighet för rättighetshavare att få information om oiThe legislator accords the protection of intellectual property a high priority. It is considered essential for society's progress, as it is conducive to innovation and investment. The illegal online file-sharing has brought on new challenges for copyright protection, particularly as identifying infringers is becoming increasingly challenging with today's technology. Therefore, a legal fram
Background: Helicobacter pylori (Hp) and its virulence factor Cytotoxin-associated gene A (CagA) have been linked to myocardial infarction (MI), but the mechanisms are unknown. This study aims to test if Hp infection and CagA are associated with pre-specified inflammatory and vascular biomarkers in patients with MI and to explore whether a broader biomarker panel can predict infection. Furthermore
Background: Limited evidence exists for effect modification of genetic characteristics on the associations of food consumption and incident type 2 diabetes (T2D). Objectives: We aimed to investigate whether the food-T2D association would vary by genetic susceptibility to metabolic traits. Methods: We analyzed data from 9542 incident T2D cases and a subcohort of 12,477 participants nested within th
Background and aims: We examined whether the excess cardiovascular disease (CVD) risk among adults with steatotic liver disease (SLD) subtypes could be reduced or eliminated through joint control of low-density lipoprotein cholesterol (LDL-C), lipoprotein(a) [Lp(a)], and high-sensitivity C-reactive protein (hs-CRP). Methods and results: This prospective cohort study included 291,995 participants f
Background: Evidence on the association between systemic glucocorticoid use and colorectal cancer (CRC) risk is limited. This study aimed to determine whether systemic glucocorticoid use is associated with an increased risk of overall CRC (diagnosed at any age) and early-onset CRC (EOCRC; diagnosed before 50 years of age). Methods: A nationwide cohort study (follow-up: 2005–2018) was conducted usi
Background: The rs738409 C -> G single nucleotide polymorphism in the patatin-like phospholipase domain-containing 3 (PNPLA3; adiponutrin) leads to a missense mutation (I148M), which is associated with increased liver fat but not insulin resistance. The I148M mutation impedes triglyceride hydrolysis in vitro, and its carriers have an increased risk of developing severe liver disease. Objective: We
Background: Previous studies have shown that high fiber intake is associated with lower mortality. However, little is known about the association of dietary fiber with specific causes of death other than cardiovascular disease (CVD). Objective: The aim of this study was to assess the relation between fiber intake, mortality, and cause-specific mortality in a large European prospective study of 452
Context: The dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits glucagon secretion at hyperglycemia but appears to enhance glucagon counterregulation during hypoglycemia in type 2 diabetes.Objective:The objective of the investigation was to study whether vildagliptin also improves α-cell function in type 1 diabetes (T1D). Patients and Methods: The study was a single-center, double-blind, ra
Klimatförändringar har amplifierats sedan den industriella revolutionen och modeller pekar på att förändringen kommer forsätta att öka åtminstone till slutet av detta århundrande. Globala temperaturer och nederbörd förväntas öka avsevärt under detta århundrade. Dessa ökningar förväntas bli särskilt markanta i de arktiska områdena. Torvmyrar belägna på höga latituder vid 0ºC isothermen, såsom Storf
Background Psychological stress is an independent risk factor for cardiovascular disease (CVD), but the mechanism by which stress is associated with CVD is not entirely understood. Although genetic factors are implied in both stress responsivity and cardiovascular reactivity, no studies to date have investigated their interactions with stress for cardiovascular end points. The objective was to elu
Objective: Little is known about midlife risk factors of future cardiac arrest. Our objective was to evaluate cardiovascular risk factors in midlife in relation to the risk of cardiac arrest (CA) of cardiac and non-cardiac origin later in life. Methods: We cross-matched individuals of the population based Malmö Diet and Cancer study (n = 30,447) with the local CA registry of the city of Malmö. Bas
Background and aims The pathogenesis of abdominal aortic aneurysm (AAA) shares several common pathways with atherosclerosis. Prospective clinical plasma biomarker studies in AAA have been hampered by the need for very large cohorts and long follow-up time. Methods We analyzed a prospective longitudinal cohort of middle-aged individuals from the cardiovascular cohort of the Malmö Diet and Cancer st
The totality of microbial genomes in the gut exceeds the size of the human genome, having around 500-fold more genes that importantly complement our coding potential. Microbial genes are essential for key metabolic processes, such as the breakdown of indigestible dietary fibres to short-chain fatty acids, biosynthesis of amino acids and vitamins, and production of neurotransmitters and hormones. D
Aims: The high mortality in untreated acute type A aortic dissection (ATAAD) stresses the need for prompt diagnosis and immediate surgical treatment. Our aim was to evaluate the frequency and clinical impact of misdiagnosis and delayed diagnosis of ATAAD. Methods and results: This was a single-centre, retrospective, observational study including all ATAAD patients with available admission charts b
