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Inappropriate surface expression of voltage-gated Ca(2+)channels (CaV) in pancreatic ß-cells may contribute to the development of type 2 diabetes. First, failure to increase intracellular Ca(2+) concentrations at the sites of exocytosis impedes insulin release. Furthermore, excessive Ca(2+) influx may trigger cytotoxic effects. The regulation of surface expression of CaV channels in the pancreatic

Bone mineral density (BMD) measurements are widely used to estimate the risk of osteoporotic fractures. In addition, many other risk factors have been identified, sonic of which are known to add to the risk independently of BMD measurements. The combination of BMD with such risk factors increases the gradient of risk/standard deviation (SD) than that achieved by BMD alone. In this paper, we report

Bone morphogenetic protein-2 (BMP2) plays a key role in bone formation and maintenance. Studies of polymorphisms within the gene in relation to bone mineral density (BMD) and fracture have been inconsistent. Our aim was to investigate associations between polymorphisms in the BMP2 gene and bone mass, fracture, and quantitative ultrasound (QUS) measures at different stages of skeletal development.

Ambulanssjukvård är en verksamhet som under de senaste decennierna successivt ombildats från att huvudsakligen transportera patienter till vårdinrättningar till att idag vara en viktig vårdgivande aktör i mobiliseringen av prehospital akutsjukvård. För att ambulanspersonal ska kunna uppfylla deras utökade arbetsuppgifter och bibehålla god patientsäkerhet i takt med ökade påfrestningar på hela ambuThe operations of emergency medical services have in the past few decades undergone a transformation from mainly transporting patients to health facilities to being a key care-giving contributor in the mobilization of prehospital care. In order for paramedics to fulfill their expanded set of tasks while maintaining good patient safety concurrently with increasing demands on the emergency medical s

Recent trends of permafrost thawing in the subarctic are expected to cause increased release of dissolved organic carbon (DOC) to inland waters, which might have cascading effects on downstream aquatic ecosystems and release of CO2 to the atmosphere. This study therefore aimed at evaluating the applicability of an empirical band ratio algorithm for estimating chromophoric dissolved organic matter

Moraxella catarrhalis, a gram negative bacterium has the rare ability to bind to immunoglobulins without inducing an immunological response. M. catarrhalis is known to cause several respiratory tract infections, such as otitis media, sinusitis and it can elevate symptoms of COPD. The immunoglobulin D (IgD)-binding protein of M. catarrhalis is a 200 kDa outer membrane autotransporter capable of bin

There is no doubt that the the Web constitutes an important channel and platform for public discourse and cultural exchange, and that our times will be remembered by accessing the archives of the Web. This is also to say, that perception of the web – present and past – is shaped and governed by the media we and our machines perceive it with. So with what media do we archive it? Recording media is

This paper is about how symphony orchestras relate to marketing principles such as the Four Ps and other similar theories adapted to better suit the need of the Arts. Arts institutions like symphony orchestras are traditionally not-for-profit organizations, but with state subsidies not growing in size with the growth of costs for symphony orchestras, they must find other ways to fund their organiz

"There's a difference between reading about things and getting into the practical" - teacher students' knowledge and expectations of the mandatory report The Social Services' investigation of child maltreatment and neglect is dependent on information from school teachers. The mandatory report requires all school personnel to report incidents involving children who may need S

Populärvetenskaplig sammanfattning: På stranden i Haväng på Österlen finns ett område precis norr om Verkeåns mynning där sanden är uppseendeväckande mörk, nästan svart på sina ställen. Söder om mynningen är sanden lika ljus som på vilken vanlig strand som helst. Det som ger denna färgskillnad är att sanden på den norra sidan av åns mynning delvis består av tunga mineral, varav några är mörka. DärAt the beach in Haväng, an area with remarkably dark sand is located just north of the outlet of Verkeån. The sand is almost black in some places. South of the outlet the sand is as light as normal beach sand. What gives this colour difference is that the sand north of Verkeån contains some heavy minerals, some of which are dark. The placer deposit contains among other minerals zircon, apatite, ru

Populärvetenskaplig sammanfattning Fenologi innebär studier av naturligt återkommande händelser som till exempel bladsprickning, knoppbristning och vissningen av blad. Det är viktigt att förstå hur klimatförändringen påverkar tidpunkten då dessa händelser sker eftersom det i sin tur påverkar kol-, närings- och den hydrologiska cykeln. Fältobservationer har varit den mest använda metoden för att saPhenology is the study of the timing of natural events such as leaf-out, bud burst and senescence relative to climate change. It is important to understand how the climate change will affect the timing of these events as it in turn affects the carbon-, nutrient- and the hydrological cycles. Field observations is the most common way to gather phenology data but the result is dependent on the skill