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Low Serum Testosterone and Estradiol Predict Mortality in Elderly Men.

Context: Age-related reduction of serum testosterone may contribute to the signs and symptoms of aging, but previous studies report conflicting evidence about testosterone levels and male mortality. No large prospective cohort study has determined a possible association between serum estradiol and mortality in men. Objective: The main objective was to examine the association between serum testoste

Effect of a primary health-care-based controlled trial for cardiorespiratory fitness in refugee women.

BACKGROUND: Refugee women have a high risk of coronary heart disease with low physical activity as one possible mediator. Furthermore, cultural and environmental barriers to increasing physical activity have been demonstrated. The aim of the study was to evaluate the combined effect of an approximate 6-month primary health care- and community-based exercise intervention versus an individual writte

FGF2 Specifies hESC-Derived Definitive Endoderm into Foregut/Midgut Cell Lineages in a Concentration-Dependent Manner.

Fibroblast growth factor (FGF) signaling controls axis formation during endoderm development. Studies in lower vertebrates have demonstrated that FGF2 primarily patterns the ventral foregut endoderm into liver and lung, whereas FGF4 exhibits broad anterior-posterior and left-right patterning activities. Furthermore, an inductive role of FGF2 during dorsal pancreas formation has been shown. However

Patterns of multiple myeloma during the past 5 decades: stable incidence rates for all age groups in the population but rapidly changing age distribution in the clinic.

OBJECTIVE: To define age-adjusted incidence trends in multiple myeloma (MM) in a well-characterized population during a long period, given that some, but not all, studies have reported increasing MM incidence over time and that clinical experience from some centers suggests an increased incidence mainly in younger age groups. PATIENTS AND METHODS: We identified all patients (N=773) with MM diagnos

Increased cartilage turnover and circulating autoantibodies in different subsets before the clinical onset of rheumatoid arthritis.

BACKGROUND: /st> Previous studies have indicated that autoantibodies may be detected years before the clinical onset of rheumatoid arthritis (RA). Cartilage biomarkers, such as cartilage oligomeric matrix protein (COMP), have not been studied previously in samples collected before the diagnosis of RA. METHODS: /st> Between 1991 and 1996, 30 447 subjects were included in the Malmö Diet Cancer Study

Elevated Serum Chemokine CXC Ligand 5 Levels Are Associated with Hypercholesterolemia But Not a Worsening of Insulin Resistance in Chinese People.

Objective: Recent study showed high chemokine CXC ligand 5 (CXCL5) is thought to be associated with insulin resistance in humans. However, evidence from large-scale populations about the relationship between serum CXCL5 level and metabolic phenotypes is scarce. Here we sought to evaluate serum CXCL5 distribution and its association with metabolic phenotypes among middle-aged and older Chinese. Res

Exploring the potential of using radio frequency identification technology in retail supply chains - A Packaging Logistics perspective

In recent years RFID technology has attracted interest from the retail industry where it is being presented as a possible key to creating more efficient and effective retail supply chains. If RFID technology is to be implemented in packaging throughout retail supply chains, there is a need to develop an understanding of how and why the technology affects activities and processes within retail supp

Global Lifestyles : Constructions of Places and Identities in Travel Journalism

This dissertation studies representations of globalization by analyzing travel journalism in two magazines from 1982 to 2008. Globalization discourses are studied through an analysis of how places and identities are constructed. The aim of this study is to examine the use of globalization discourses in travel journalism as both a construction and a defense of privilege. By focusing on two magazine

This Time It’s Personal: Social Networks, Viral Politics and Identity Management

This chapter deals with political mobilisation and participation in social media. The main focus is on the impor¬tance of Internet-mediated social networks in providing a “media filter”, functioning as a kind of collective gatekeeper to spread news and information perceived as important, in contrast to the image of the single individual media consumer faced with an in¬surmount¬able mass of informa

Quality indicators within the use of open educational resources in higher education

A paradigm shift is emerging in higher education especially regarding how universities should address personalized and collaborative mobile learning. Experiences from three international benchmarking-projects through the European Association of Distance teaching Universities (EADTU), the European Centre for Strategic Management of Universities (ESMU) and the First dual mode benchmarking club on qu

Nurse managers' professional networks, psychosocial resources and self-rated health.

Background. Nurse managers act under constant pressure to develop strategies in response to professional challenges within a changing and restructured health care system. When such environmental stress is present, they need access to sufficient psychosocial recourses. Aim. The study aimed to investigate whether nurse managers' professional networks, psychosocial work conditions, job support, soci

Urbanwater management vs. climate change: Impacts on cold region waste water inflows

Failure to account for non-climatic changes to water systems, such as design and operation, within climate change impact assessments leads to misconceptions because these activities buffer the human built enviroment from bio-physical impacts. Urban drainage in cold regions, which is dominated by snowmelt, is especially vulnerable to climate change and is investigated in this paper within the conte

Annual screening detects celiac disease in children with type 1 diabetes

Objective: To investigate the prevalence of celiac disease (CD) in a cohort of type 1 diabetes mellitus (T1DM) children and adolescents at the time of clinical diagnosis and to evaluate the screening procedure and possible role of human leukocyte antigen (HLA)-DQ during a 5-yr follow-up. Research design and methods: The study group was a cohort of 300 newly diagnosed T1DM children and youths young