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Plasma C4d levels correlate with treatment response and renal activity in proliferative lupus nephritis

Objective The investigation of complement factors in lupus nephritis (LN) in relation to treatment response and the impact of underlying genetics of C4. Methods Seventy-seven patients with active LN confirmed by a kidney biopsy and in whom second biopsies had been performed after immunosuppressive treatment were included. Complement factors C3, C4, C4d and C4d/C4 ratio were evaluated at the biopsy

Health and economic benefits of energy, urban planning, and food interventions that lower greenhouse gas emissions

Public health can be immediately and substantially improved by policies that also mitigate climate change over the longer term. However, implementation of these policies has been slowed at least in part by doubts and lack of awareness of these health co-benefits. To address this barrier to progress, we demonstrate how an illustrative set of interventions led to environmental, health, and economic

Seasonal Dynamics of Brownification Mitigation in Constructed Wetlands

Increasing total organic carbon (TOC) concentrations concurrent with a darkening in water colour in boreal freshwaters is called brownification. This can affect crucial ecosystem services. Our study investigated constructed wetland optimisation regarding depth and water residence time (WRT) during different seasons to remedy dark water colour and high TOC concentrations, while retaining nitrogen r

Feasibility of a Person-Centred Nursing Model Targeting Patient and Family Caregiver Needs in Allogeneic Haematopoietic Stem Cell Transplantation

Background/Objectives: Undergoing intensive cancer treatment, such as allogeneic haematopoietic stem cell transplantation, challenges the entire life situation of patients and their family caregivers. A prerequisite for effective care is that interventions are tailored to the unique circumstances of each individual. The aim of this study was to examine the feasibility of a developed person-centred

Macroscopic findings in collagenous colitis : A multi-center, retrospective, observational cohort study

Background Collagenous colitis (CC) is by definition a histological diagnosis. However, colonoscopy often reveals characteristic endoscopic findings. The aim of this study was to evaluate the frequency and type of endoscopic findings in patients diagnosed with CC in 4 participating centers. Methods This was a retrospective study; the databases of 2 university hospitals in Edinburgh (Scotland) and

Funding models in palliative care : Lessons from international experience

Background: Funding models influence provision and development of palliative care services. As palliative care integrates into mainstream health care provision, opportunities to develop funding mechanisms arise. However, little has been reported on what funding models exist or how we can learn from them. Aim: To assess national models and methods for financing and reimbursing palliative care. Desi

Effect of oxygen therapy on myocardial salvage in ST elevation myocardial infarction : the randomized SOCCER trial

OBJECTIVE: Recent studies suggest that administration of O2 in patients with acute myocardial infarction may have negative effects. With the use of cardiac MRI (CMR), we evaluated the effects of supplemental O2 in patients with ST elevation myocardial infarction (STEMI) accepted for acute percutaneous coronary intervention (PCI).MATERIALS AND METHODS: This study was a randomized-controlled trial c

Insulin secretion and action in North Indian women during pregnancy

AIM: The relative roles(s) of impaired insulin secretion vs. insulin resistance in the development of gestational diabetes mellitus depend upon multiple risk factors and diagnostic criteria. Here, we explored their relative contribution to gestational diabetes as defined by the WHO 1999 (GDM1999) and adapted WHO 2013 (GDM2013) criteria, excluding the 1-h glucose value, in a high-risk Indian popula

Programkoordinatorn som interface : Om att odla kvalitet och praktikgemenskap vid universitetet

This report discusses the role of the program coordinator in a faculty where the organisation of connected and integrated courses in bachelor programmes is a fairly new phenomenon. In the Faculties of Humanities and Theology at Lund University there has been a strong tradition to design an individual bachelor exam by combining independent courses. During the last ten years an increasing number of

Higher prevalence of type 2 diabetes in men than in women is associated with differences in visceral fat mass

Context: We have previously found that visceral fat is a stronger predictor for cardiovascular risk factors than body mass index (BMI). Objective: This study sought to investigate the prevalence of diabetes in elderly men and women in relation to objectively assessed visceral fat volume. Design and Setting: The cohort consisted of a population-based sample of 705 men and 688 women, all age 70 y at

A kaleidoscope of interactions. : Researching and presenting processes of opera improvisation.

The artistic doctoral project Singing in action – processes of vocal improvisation is an investigation of vocal improvised performance from my point of view as a classically trained singer and vocal improviser. It focuses on an artistic tradition which has its roots in medieval Provence and Italy (Wilén, 2013a) and which is an expanding classical vocal genre of today: opera and art song improvisat

General purpose technology diffusion and labour market dynamics : A spatio-temporal perspective

This dissertation aims at advancing the knowledge about the role of the labour market in the process of the technology-induced economic transformation, taking into account the variety of factors involved at micro-, meso-, and macro-levels of the economy and at different geographical scales. Empirically, the dissertation investigates the co-evolutionary dynamics of industrial restructuring and work

Acute uncomplicated diverticulitis managed without antibiotics–difficult to introduce a new treatment protocol but few complications

Objective: Routine antibiotic treatment of acute uncomplicated diverticulitis (AUD) has been shown ineffective. In this study, the adherence to a new treatment protocol for uncomplicated diverticulitis was evaluated and the incidence of complications in patients treated with and without antibiotics was investigated. Materials and methods: A retrospective study of in-patients diagnosed with AUD at

BIM Inertia: Contracts & Behaviours

Whilst Building Information Modelling (BIM) promises significant improvements in construction quality and efficiency, current contractual models do not encourage its use; indeed actively inhibit the collaboration at its core. To help bring BIM into the mainstream, it is claimed we need to re-craft existing contractual relationships to facilitate collaborative decision making and to equitably alloc