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Gender equality in the work of local research ethics committees in Europe: a study of practice in five countries

Background: Funding organisations and research ethics committees (RECs) should play a part in strengthening attention to gender equality in clinical research. In the research policy of European Union (EU), funding measures have been taken to realise this, but such measures are lacking in the EU policy regarding RECs. Objective: To explore how RECs in Austria, Germany, Ireland, The Netherlands and

Health care consumption and place of death among old people with public home care or in special accommodation in their last year of life.

BACKGROUND AND AIMS: Developing care for older people in the last phase of life requires knowledge about the type and extent of care and factors associated with the place of death. The aim of this study was to examine age, living conditions, dependency, care and service among old people during their last year of life, but also their place of death and factors predicting it. METHODS: The sample (n=

Ålder och ekonomisk omvandling. Sveriges tillväxthistoria i ett demografiskt perspektiv, 1890-1995

Den svenska arbetskraften har blivit äldre under 1900-talet. Under vissa perioder har denna åldrandeprocess accelererat, medan den har avtagit under andra perioder. I denna studie undersöks vilken roll dessa förändringar i åldersstrukturen spelar för genomsnittlig arbetsproduktivitet och ekonomisk tillväxt. Olika åldersgrupper besitter olika typer av humankapital, eftersom den individuella produkt

NIKE: a new clinical tool for establishing levels of indications for cataract surgery

Purpose: The purpose of this study was to construct a new clinical tool for establishing levels of indications for cataract surgery, and to validate this tool. Methods: Teams from nine eye clinics reached an agreement about the need to develop a clinical tool for setting levels of indications for cataract surgery and about the items that should be included in the tool. The tool was to be called 'N

Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.

MMPs are generally considered to regulate degradation and remodeling of the ECM. Convincing data also implicate a role for MMPs in inflammatory conditions, such as AP, although the mechanisms are not known. The aim of this study was to define the role of MMPs in regulating activation of trypsinogen and tissue damage in AP, which was induced by infusion of taurocholate into the pancreatic duct in m

A Pharmacokinetic and Dosing Study of Intravenous Insulin-Like Growth Factor-I and IGF-Binding Protein-3 Complex to Preterm Infants.

In preterm infants, low levels of Insulin like growth factor 1 (IGF-I) have been associated with impaired growth and retinopathy of prematurity. Our objective was to study safety and pharmacokinetics of intravenously administered rhIGF-I with its binding protein 3 (rhIGFBP-3) to preterm infants. At 3 days chronological age, an intravenous 3 hours infusion of rhIGF-I/rhIGFBP-3 was administered foll

Prophylaxis in von Willebrand disease.

This paper reviews current issues regarding short-term (i.e. for surgery and invasive procedures) and long-term (i.e. regular infusions to prevent bleeding on a permanent or temporary basis) prophylaxis treatment using replacement concentrates for patients with von Willebrand disease (VWD) who do not respond satisfactorily to desmopressin. The standard treatment of these patients is with factor co

Meta-managing: A Study on How Superiors and Subordinates Manage Their Relationship in Everyday Work

In virtually every organization we find formally appointed managers, but nevertheless we tend to condemn the idea of formal hierarchy and celebrate alternative modes of governance that better respect the discretion of employees. This tension, that seemingly surrounds the vertical dimension of contemporary organizations, forms the backdrop of this study which examines how superiors and subordinates

Tehnology Shift and Long term Growth in Regions

Abstract The overarching aim of this paper is to investigate the importance of technological shifts and national macroeconomic preconditions for long term growth and structural transformation in various regions in a national regional system. Intrinsic to this, the issue and origin of divergence and convergence coming in repetitive waves in regional systems will be discussed as a possible contribut