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Introduction: Heterogeneity in cognitive outcomes and response to treatment has been described in Alzheimer’s disease (AD). Using the method of mixed models, higher resolution can be obtained to identify potential predictors of long-term outcomes. Aims: To analyse the impact of the APOE genotype, non-steroidal anti-inflammatory drug (NSAID) therapy and cholinesterase inhibitor treatment (ChEI) on
The aim of this study is to systematically compare parametric and non-parametric techniques for analyzing trends in annual NDVI derived from NOAA AVHRR sensor in order to examine how trend type and departure from normality assumptions affect the accuracy of detecting long-term change. To generate annual data, the mean NDVI of a four-month long ‘green’ season was computed for fifteen sites (located
Emelie Rohne EKHK18 Bachelor’s thesis (15 credits ECTS) June 2012 Supervisor: Tobias Karlsson Examiner: Benny Carlson Bachelor’s of Science Program in Development Studies Public Works Programs as a Development Strategy for Marginalized Groups: A case study of tribal MNREGA-participants in Wayanad, Kerala Abstract: In recent years, the practice of adopting Public Works Programs (PWPs) as a developm
https://www.sasnet.lu.se/sites/sasnet.lu.se/files/emelie_rohne_bachelors_thesis.pdf - 2026-08-25
ORIGINAL PAPER Achieving Standardized Medication Data in Clinical Research Studies: Two Approaches and Applications for Implementing RxNorm Rachel L. Richesson & Susan B. Smith & Jamie Malloy & Jeffrey P. Krischer Received: 16 December 2008 /Accepted: 15 March 2009 /Published online: 3 April 2009 # Springer Science + Business Media, LLC 2009 Abstract The National Institutes of Health has proposed
https://www.teddy.lu.se/sites/teddy.lu.se/files/06032016_679_07_richesson_jms_2010.pdf - 2026-08-25
Extending Classification Algorithms to Case-Control Studies Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attrib
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-12/106%2009192019_679_106_MP206_Stanfill_BECB_2019.pdf - 2026-08-25
Background: Symptom control by drug treatment is the most important task in routine clinical care of patients with schizophrenia. Structured assessment methods are needed in this task but not used much. The US-developed Positive and Negative Syndrome Scale (PANSS) is a standard tool for symptom assessment. The Psychosis Evaluation tool for Common use by Caregivers (PECC) was constructed in Europe
Aims/hypothesis Type 2 diabetes is characterised by progressive loss of pancreatic beta cell mass and function. Therefore, it is of therapeutic interest to identify factors with the potential to improve beta cell proliferation and insulin secretion. Bone morphogenetic protein 4 (BMP4) expression is increased in diabetic animals and BMP4 reduces glucose-stimulated insulin secretion (GSIS). Here, we
Recurrent prostate cancer remains a major clinical challenge. The lysine specific demethylase-1 (LSD1/KDM1A), together with the JmjC domain-containing JMJD2A and JMJD2C proteins, have emerged as critical regulators of histone lysine methylation. The LSD1-JMJD2 complex functions as a transcriptional co-regulator of hormone activated androgen and estrogen receptors at specific gene promoters. LSD1 a
The importance of the home environment increases with age. Perceived aspects of home influence life satisfaction, perceived health, independence in daily activities and well-being among very old people. However, research on health and perceived aspects of home among senior citizens in earlier phases of the aging process is lacking. Therefore, the main aim was to explore whether perceived aspects o
We describe the new microsporidium Hamiltosporidium tvaerminnensis gen. et sp. nov. with an emphasis on its ultrastructural characteristics and phylogenetic position as inferred from the sequence data of SSU rDNA, alpha-and beta-tubulin. This parasite was previously identified as Octosporea bayeri Jirovec, 1936 and has become a model system to study the ecology, epidemiology, evolution and genomic
cAMP-response element-binding protein (CREB) is required for the induction of adipogenic transcription factors such as CCAAT/enhancer-binding proteins (C/EBPs). Interestingly, it is known from other tissues that LKB1 and its substrates AMP-activated protein kinase (AMPK) and salt-inducible kinases (SIKs), negatively regulate gene expression by phosphorylating the CREB co-activator CRTC2 and class
A desire for higher speed and performance in molecular profiling analysis at a reduced cost is driving a trend in miniaturization and simplification of procedures. Here we report the use of a surface acoustic wave (SAW) atomizer for fast sample handling in matrix-assisted laser desorption ionization mass spectrometry (MALDI MS) peptide and protein profiling of Islets of Langerhans, for future type
Internet har under det senaste årtiondet blivit ett modernt inslag i nästan varje människas vardag. Internet ger obegränsade kommunikationsmöjligheter, men det finns också ett antal negativa sidor med internets snabba utveckling i samhället. En av dessa negativa sidor är att folk under den senaste tiden har börjat utnyttja möjligheten att bakom en datorskärm anonymt kränka personer som de kanske iThe Internet has during the last decade become a modern feature in almost every person’s everyday life. The internet gives an unlimited possibility for communication, but there is also a number of negative aspects with the Internet’s fast development in society. One of these negative aspects is that very recently people have started to use the possibility to hide behind a screen and anonymously vi
Traditionsprincipen har tillämpats sedan lång tid tillbaka, detta trots att den saknar stöd i lag. Huvudregeln är att en köpare vinner sakrättsligt skydd mot säljarens borgenärer genom att ta den köpta egendomen i besittning. Således räcker det inte med ett köpeavtal för att köparen ska få sakrättsligt skydd mot säljarens borgenärer vid en konkurs eller utmätning. Det finns författare i doktrinenThe doctrine of tradition has been applied for a long time, even though it has no basis in law. The general rule is that a buyer wins protection against the seller's creditors by taking possession purchased of the property. Thus is a purchase contract not enough for the buyer to get right in rem against the seller’s creditors in a bankruptcy or foreclosure. There are authors in the doctrine t
