AimImpaired vibrotactile sense, mirroring diabetic peripheral neuropathy, is present among children and adolescents with type 1 diabetes. This study aims to re-examine the vibrotactile sense of paediatric type 1 diabetes subjects in order to evaluate any alterations in the vibrotactile sense over time.MethodsA VibroSense Meter I device was used to determine the vibrotactile perception thresholds (

The focus on cancer rehabilitation has increased, but breast cancer patients still report unmet rehabilitation needs. Since many women today will live long beyond their diagnosis, there are multiple challenges for the healthcare system in supporting these women in their new life situation. A more individualized approach is seen as necessary to optimize the rehabilitation for survivors. Pathographi

Are there indications for the neoliberal hegemony in economy and society to come to an end? Are people already imagining a future within environmental limits and beyond the growth imperative? Theoretically, building upon Marx and Bourdieu, we reconstruct the ideological impact that capitalism, in general, and neoliberalism, in particular, has on the ways we think, feel and make sense of our enviro

Several pharmacogenetics studies have identified an association between a greater metformin-dependent reduction in HbA1c levels and the minor A allele at rs2289669 in intron 10 of SLC47A1, encoding multidrug and toxin extrusion 1 (MATE1), a presumed metformin transporter. It is currently unknown if the rs2289669 locus is a cis-eQTL, which would validate its role as predictor of metformin efficacy.

What is sex work? I have decided to start this short contribution with a question, which I think the reader should answer before continuing. So what is sex work? Is it a legitimate form of work or is it a job whose only characteristics are exploitation, harassment, and coercion? Also, can a person (woman or man) freely decide to be a sex worker or is it impossible to engage in such profession with

This article discusses and analyzes an unusual construction in Icelandic, with a plural pronoun in the singular reading and a directly juxtaposed or annexed NP (or DP), where, for example, vio Ólafur (literally "we.nom Olaf.nom") means 'Olaf and I'. We refer to this construction as Pro[NP]. Pro[NP] constructions have been reported for a handful of languages that lack a case system. Icelandic, in c

Juice-pressing residues, among them blackcurrant pomace, are valuable materials for being upgraded in food products. Their excellent nutritional profiles in line with their functional properties allow a wide range of applications. The current study was performed to evaluate the overall liking of a pomace-enriched thin crispy-baked bread product in five European countries, and to obtain suggestions

Fungal infections are a major health problem that often begin in the gastrointestinal tract. Gut microbe interactions in early childhood are critical for proper immune responses, yet there is little known about the development of the fungal population from infancy into childhood. Here, as part of the TEDDY (The Environmental Determinants of Diabetes in the Young) study, we examine stool samples of

The exact spatial and temporal behaviour of rapid climate shifts during the Last Glacial– Interglacial Transition are still not entirely understood. In order to investigate these events, it is necessary to have detailed palaeoenvironmental reconstructions at geographically spread study sites combined with reliable correlations between them. Tephrochronology, i.e., using volcanic ash deposits in ge

The Hyogo and Sendai frameworks stress that risk assessments should inform plans. However, it is unclear how, in theory, risk assessments and plans are conceptually related and how, in practice, they inform each other. This study aims to fill this knowledge gap. Conceptually, it proposes an explicit link between risk assessments and plans via the capability of the responding organisation and its e

Insulin resistance and lower muscle quality (strength divided by mass) are hallmarks of type 2 diabetes (T2D). Here, we explore whether alterations in muscle stem cells (myoblasts) from individuals with T2D contribute to these phenotypes. We identify VPS39 as an important regulator of myoblast differentiation and muscle glucose uptake, and VPS39 is downregulated in myoblasts and myotubes from indi

Material decomposition in computed tomography is a method for differentiation and quantification of materials in a sample and it utilizes the energy dependence of the linear attenuation coefficient. In this study, a post-image reconstruction material decomposition method is constructed for a low-energy micro-CT setup using a photon counting x-ray detector. The low photon energy range (4–11 keV) al

Syfte: Cancerforskning och relaterade innovationsprocesser saknar ofta en viktig komponent; patientdeltagande. Vi nyanalyserar tre studier (a-c) för att undersöka hur teorin Nuets förnöjsamhet kan användas för att förbättra patientens deltagande och psykosociala hälsa.Metod: Vi återanalyserade data från den klassiska grundade teoristudien om Nuets förnöjsamhet, baserad på fyra års observation och Purpose: Cancer research and connected innovation processes often lack a major component; patient participation. We revisit three studies (a-c) in order to explore how Momentary contentment theory may be used to improve patient participation and psychosocial health.Method: We revisited data from the initial (a) classic grounded theory study on Momentary contentment, based on four years of observat

Patients suffering from systemic lupus erythematosus (SLE) are at increased risk of developing cardiovascular disease (CVD) and traditional therapies including statins provide insufficient protection. Impaired removal of apoptotic material is a common pathogenic mechanism in both SLE and atherosclerosis and is considered to be a key factor in the development of autoimmunity. Since oxidized LDL and