Filtyp
The downscaling of environmental responsibilities poses new challenges for regional governments, necessitating an evolution in their roles to manage environmental policy alongside traditional local development duties. This paper draws on the concept of the entrepreneurial state and on the idea of the ‘entrepreneurial region’ to explore how local and regional governments implement bioeconomy polici
Purpose: Surgical repair of parastomal hernias (PH) is challenging, mainly due to high recurrence rates. The Local Parastomal repair (LoPa) is a novel technique utilizing a retromuscular synthetic mesh with an outward-facing collar. This study describes the LoPa technique and evaluates its outcomes. Methods: This single-centre study retrospectively reviewed 39 consecutive patients who underwent Lo
Wastewater-based surveillance (WBS) allows the analysis of pathogens, chemicals or other biomarkers in wastewater to derive unbiased epidemiological information at population scale. After re-gaining attention during the SARS-CoV-2 pandemic, the field holds promise as a surveillance and early warning system by tracking emerging pathogens with pandemic potential. Expanding the current toolbox of ana
Introduction: Child abuse is a global public health problem. It poses a threat to both physical and psychosocial well-being, resulting in serious consequences for the child, the family, and society. Radiographers are in a unique position to identify children at risk. In clinical practice, they may observe unusual interactions between children and their caregivers during radiographic procedures or
Epithelial-to-mesenchymal transition (EMT), driven by cues from the tumor microenvironment, is a critical initiator of metastatic progression. In breast cancer patients, elevated expression of cartilage oligomeric matrix protein (COMP) is associated with shorter survival and increased metastatic risk. Here, we investigated the role of COMP in regulating EMT in breast cancer. Breast cancer cells tr
Walking is a primary mode of transport in urban Africa, yet it remains unsafe, challenging, and unpleasant. In contrast, several European countries have implemented systematic policies to promote walking through Safe System principles. This study compares pedestrian safety in three African countries (Tanzania, Ghana, Zambia), with three European countries with excellence in road safety and Safe Sy
Denna forskningsrapport inom ramen för ett MSB uppdrag identifierar och kartlägger relevanta datamängder för att bedöma tvärsektoriella sårbarheter för samhällsviktiga verksamheter och kritiska infrastrukturer på nationell svensk nivå. Totalt identifierades 108 datamängder, varav 49 bedöms vara relevanta för analyser på nationell nivå, 54 på regional nivå och 37 på lokal nivå. Identifierad och sam
Micropollutant removal is a key component of the revised Urban Wastewater Treatment Directive (UWWTD) and can be achieved with ozonation. During ozonation, the composition of the wastewater matrix and the targeted treatment level for individual micropollutants or groups of such compounds affect ozone consumption. In this work, it was hypothesized that nitrite scavenging, the point of dosing (befor
Aims: Testing insulin resistance could help improve physician assessment of patients’ risk of prediabetes or type 2 diabetes (T2D), even among normoglycemic individuals. Methods: The longitudinal study followed 16,333 normoglycemic participants in a nation-wide employer-sponsored health assessment program starting in August 2020 with a median follow-up time of 2.9 years for incident prediabetes or
Background: Early electrocardiograph predates electronic amplification and therefore required innovative and highly sensitive instrumentation. Willem Einthoven's introduction of the string galvanometer in 1903 enabled recording of clinically useful electrocardiograms and established electrocardiography as a diagnostic method. Objectives: To describe the provenance and technical features of a uniqu
The islet β cells are the specific targets in an autoimmune process that eventually leads to the clinical onset of type 1 diabetes (T1D). The etiology is related to human leukocyte antigen (HLA) DR-DQ genetic factors that are necessary but not sufficient for disease development. The environmental etiology is related to enterovirus infection in early childhood resulting in two endotypes. In HLA DR4
BACKGROUND: Accreditation of cancer centres aims to deliver high-quality, person-centered care and underscores the integration with education, research, and innovation. Over the past decade, cancer centres in the Nordic countries have engaged in accreditation processes through the Organisation of European Cancer Institutes (OECI).OBJECTIVE: This study provides an overview of a rapidly evolving lan
”Människor och vilt i Skandinavien” syftar till att beskriva och illustrera hur samtida samhällsvetenskaplig och humanistisk forskning närmar sig frågor om vilt och viltförvaltning i Skandinavien. Rapporten består av två delar där Del 1 beskriver olika discipliner och deras teoretiska utgångspunkter och centrala frågeställningar inom forskningsfältet. Disciplinerna kategoriseras grovt utifrån den “Humans and Wildlife in Scandinavia” aims to describe and illustrate how contemporary social science and humanities research approaches issues related to wildlife and wildlife management in Scandinavia. The report consists of two parts. Part 1 describes the different disciplines and their theoretical foundations as well as central research questions within the field. The disciplines are broadly ca
Introduction: Wearable sensors measuring bodily movements used in free-living conditions may help predict falls in older persons. Assessing their use in this context is essential to identify potential challenges related to fall risk screening. Therefore, this study aimed to assess the feasibility of conducting a prospective study comparing self-rated and wearable sensor-based measures for the asse
Skin wounds remain a clinical challenge, especially for burns and chronic wounds, and existing therapies seldom re-engage the rapid, scar-sparing repair programs observed in nature. Planarians are super-regenerators capable of rebuilding the entire organism from small fragments, and their extracellular vesicles might encode potent prorepair cues. But whether planarian-derived extracellular vesicle
The Varena Iron Ore deposit in the SW East European Craton is a significant ore body that occurs within metamorphosed and hydrothermally reworked Paleoproterozoic dolostones. We have performed microstructural investigations supplemented with mineral chemistry and geochronological investigations (LA-ICP-MS) to obtain age constraints on the ore-forming event(s) and improve the understanding of the c
Partitioned polygenic scores (pPS) have been developed to capture pathophysiologic processes underlying type 2 diabetes (T2D). We investigated the association of T2D pPS with diabetes-related traits and T2D incidence in the Diabetes Prevention Program. We generated five T2D pPS (b-cell, proinsulin, liver/lipid, obesity, lipodystrophy) in 2,647 participants randomized to intensive lifestyle, metfor
