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Applicability of Clinical Trials in an Unselected Cohort of Patients With Intracerebral Hemorrhage

BACKGROUND AND PURPOSE—: Patient selection in clinical trials on intracerebral hemorrhage (ICH) affects overall applicability of results. We estimated eligibility for completed, ongoing, and planned clinical trials in an unselected cohort of patients with ICH. METHODS—: Large clinical ICH trials were identified using trial registration databases. Each trial’s inclusion criteria were applied to a c

CSR: retailer activities vs. consumer buying decisions

Purpose– The purpose of this paper is to investigate how a retailer’s corporate social responsibility (CSR) activities and image influence consumer perceptions regarding the firm’s social responsibility, and how CSR aspects influence consumers buying decisions in store for a specific product.Design/methodology/approach– A qualitative case study method is used, including interviews, document studie

Time and Space in Event Behaviour: Tracking Visitors by GPS

Research on tourist mobility in combination with the tourists’ experiences has been rare to date. Previous studies focusing on the activities of tourists in time and space have most often used the method of time–space diaries. However, an important flaw in this method is that these recordings depend on the respondents’ personal observations and notes. This disadvantage is avoided by using Global P

Remaining divides : Access to and use of ICTs among elderly citizens

The ambition to make all kinds of societal services, public as well as commercial ones, more effective and accessible via online applications is reoccurring all over the western world. To a large extent, such ambitions hold the promise to make citizens’ everyday lives easier, but they are, however, also problematic in that they presuppose a number of important prerequisites. They presuppose widesp

Does prior start-up experience matter for entrepreneurs’ learning? : A comparison between novice and habitual entrepreneurs

Purpose– This paper aims to present a study of the role of prior start‐up experience as a source of learning in the entrepreneurial process. Three learning outcomes are examined with respect to a comparison between habitual and novice entrepreneurs: skills for coping with liabilities of newness, preference for effectual reasoning, and attitudes towards failure.Design/methodology/approach– This is

Libraries, democracy, information literacy, and citizenship : An agonistic reading of central library and information studies’ concepts

PurposeThe purpose of this paper is to advocate and contribute to a more nuanced and discerning argument when ascribing a democratic role to libraries and activities related to information literacy.Design/methodology/approachThe connections between democracy and libraries as well as between citizenship and information literacy are analysed by using Mouffe’s agonistic pluralism. One example is prov

Correlates of leisure time physical inactivity in a scandinavian population : A basis for interventions

Background: Effective interventions are needed to increase physical activity in the general population. To target interventions, we need knowledge of insuffciently active groups in society. This study aims to identify demographic and health-related correlates of leisure-time physical inactivity in a general Scandinavian population. Methods: Study participants comprised 5734 control subjects, age 1

Information, social support and coping in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension-A nationwide population-based study

Objective: Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) decrease life expectancy for affected patients. The aim was to describe the perceptions of received information regarding diagnosis, treatment and management, as well as social support and coping perceived by patients with PAH or CTEPH. Methods: A descriptive, national cohort survey that incl

Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications

The changes in life-style with increased access of food and reduced physical activity have resulted in the global epidemic of obesity. Consequently, individuals with type 2 diabetes and cardiovascular disease have also escalated. A central organ in the development of diabetes is the pancreas, and more specifically the pancreatic beta cells within the islets of Langerhans. Beta cells have been assi

Molecular crowding impacts the structure of apolipoprotein A-I with potential implications on in vivo metabolism and function

The effect molecular crowding, defined as the volume exclusion exerted by one soluble inert molecule upon another soluble molecule, has on the structure and self-interaction of lipid-free apoA-I were explored. The influence of molecular crowding on lipid-free apoA-I oligomerization and internal dynamics has been analyzed using electron paramagnetic resonance (EPR) spectroscopy measurements of nitr

Partial disruption of lipolysis increases postexercise insulin sensitivity in skeletal muscle despite accumulation of DAG

Type 2 diabetes and skeletal muscle insulin resistance have been linked to accumulation of the intramyocellular lipid-intermediate diacylglycerol (DAG). However, recent animal and human studies have questioned such an association. Given that DAG appears in different stereoisomers and has different reactivity in vitro, we investigated whether the described function of DAGs as mediators of lipid-ind

Genome-wide association study of the modified stumvoll insulin sensitivity index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

Genome-wide association studies (GWAS) have found few common variants that influence fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated assessment of fasting and dynamic measures of insulin sensitivity would detect novel common variants. We performed a GWAS of the modified Stumvoll Insulin Sensitivity Index (ISI) within the Meta-Analyses of Glucose and Insulin-Re

Insufficient time for leisure and perceived health and stress in working parents with small children

BACKGROUND: More knowledge about how recovery may promote health among parents with small children is needed.OBJECTIVE: To explore whether insufficient time for leisure was associated with poorer perceived health and higher stress in working parents. A further aim was to explore potential gender differences in the association between insufficient time for leisure and poor perceived health.METHODS: