Filtyp
Socio-economic differences in health and mortality are substantial and increasing today in many developed countries. The sources of these differences remain debated. There is an expanding literature showing that early-life conditions are linked to health in adulthood and old age. However, our knowledge about whether beneficial treatments in early life influence later health is still limited. Using
Objective. Previous research has shown that elderly and disabled travelers using Special Transportation Services (STS) are injured without being involved in a vehicle crash. In order to estimate the true costs for these vehicle-related injuries, the focus needs to be adjusted towards an incident/traveler-oriented perspective. The aim of the project was thus to utilize such a perspective, in order
Recent genome-wide association studies confirm that human leukocyte antigen (HLA) genes have the strongest associations with several autoimmune diseases, including type 1 diabetes (T1D), providing an impetus to reduce this genetic association to practice through an HLA-based disease predictive model. However, conventional model-building methods tend to be suboptimal when predictors are highly poly
I denna rapport analyseras effekterna av sänkta parkeringsnormer för bostäder för invånarna i det centrumnära, och relativt nybyggda, bostadsområdet Porslinsfabriken i Göteborg. Porslinsfabriken är med en relativt låg parkeringsnorm på 0,57 platser per lägenhet ett bra exempel på en parkeringspolitik som förs i alltfler kommuner. Resultatet visar att 19 procent av hushållen har minskat bilinnehave
Do forest owners’ levels of education or value profiles explain their responses to climate change? The cultural cognition thesis (CCT) has cast serious doubt on the familiar and often criticized "knowledge deficit" model, which says that laypeople are less concerned about climate change because they lack scientific knowledge. Advocates of CCT maintain that citizens with the highest degrees of scie
In the home garden, people inevitably interact with a multitude of non-human actors, including plants. Home gardeners get involved with, and affect, the growth, life and death of other individuals through activities such as weeding and pruning. In this article, the authors discuss people’’s everyday interactions with ‘‘nature’’ in their own gardens, with a specific focus on plants. Despite their r
Serotonin (5-HT) is a biogenic monoamine that functions both as a neurotransmitter and a circulating hormone. Recently, the metabolic effects of 5-HT have gained interest and peripheral 5-HT has been proposed to influence lipid metabolism in various ways. Here, we investigated the metabolic effects of 5-HT in isolated, primary rat adipose cells. Incubation with 5-HT suppressed β-adrenergically sti
Recent studies report trends of strongly increasing iron (Fe) concentrations in freshwaters. Since Fe is a key element with a decisive role in the biogeochemical cycling of major elements, it is important to understand the mechanisms behind these trends. We hypothesized that variations in Fe concentration are driven mainly by redox dynamics in hydraulically connected soils. Notably, Fe(III), which
Combinations of genetic and environmental factors contribute to the pathogenesis of type 2 diabetes (T2D); however, our knowledge of the molecular mechanisms by which these factors trigger diabetes is still limited. While genome-wide association studies have identified and characterized more than 60 genomic loci associated with T2D, recent methylome charts and reference regulatory maps obtained fr
The associations of body mass index (BMI) and other anthropometric measurements with lung cancer were examined in 348,108 participants in the European Investigation Into Cancer and Nutrition (EPIC) between 1992 and 2010. The study population included 2,400 case patients with incident lung cancer, and the average length of follow-up was 11 years. Hazard ratios were calculated using Cox proportional
Digital research data is often advanced as a trouble-free concept and used to describe the material of research at all stages in a research process. However frequently such framing lacks understanding of the roles of disciplinary and organisational cultures, and of what the various practices, including those of funding policy and university administration, involved in shaping what research data ar
