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Most signals detected by genome-wide association studies map to non-coding sequence and their tissue-specific effects influence transcriptional regulation. However, key tissues and cell-types required for functional inference are absent from large-scale resources. Here we explore the relationship between genetic variants influencing predisposition to type 2 diabetes (T2D) and related glycemic trai

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing Coronavirus Disease 19 (COVID-19), emerged at the end of 2019 and quickly spread to cause a global pandemic with severe socio-economic consequences. The early sequencing of its RNA genome revealed its high similarity to SARS, likely to have originated from bats. The SARS-CoV-2 non-structural protein 10 (nsp10) displays high sequ

The rationale was to longitudinally follow-up interviews performed with heart recipients at their one-year examination in order to deepen the understanding of the meaning of surviving a heart transplant. The aim was to explore the meaning of surviving three years after a heart transplant compared to one year and to identify what constitutes the change process. A phenomenological–hermeneutic method

Food additives such as emulsifiers are used in increasing quantities in the food industry. The aim of this study was to compare three different emulsifiers (polysorbate 80 (P80), carboxymethyl cellulose (CMC), and β-lactoglobulin (β-lac) with regards to their effect on the stimulation of immune cells and intestinal permeability. The immune stimulatory effects were studied in the myeloid cell line

During the last decade, personal assistance programs have suffered from cutbacks, resulting in a public debate about the future of the service. This debate has largely been framed by public commission estimations of the level of incorrect personal assistance payments, where the idea that circa 10% of all assistance payments are incorrect repeatedly has been used to justify measures designed to dec

On social media platforms, such as blogs, the boundaries between private life and working life can be blurred. When social media is used by people who can be seen as agents for human service organizations this can give rise to both ethical and relational issues. On the one hand socialworkers like everyone else should have the right to express opinions and act as private persons on the internet. On

Detta är en kombinerad kvantitativ och kvalitativ studie om gymnasieelevers instrumentval. I denna undersökning kommer elevernas egen åsikt att bli hörd i fråga om varför, vad och hur de gör när de väljer sina instrument. Hur ser elever på sina egna och andras val av instrument? Vilka faktorer finns det som påverkar elever i deras instrumentval? Om det är så att tjejer och killar väljer olika instThis is a mixed method research study about the instrument choices of upper secondary school students. The students’ own opinion regarding instrument choices is examined. Factors such as why and how a particular instrument has been chosen have been discussed. How do the students look at their own and others’ choice of instrument? What factors influence their choices? What does the distribution of

With today’s focus on the world’s environmental issues, it is important for organizations and companies to find a way to give their commitment credibility. By certification according to ISO 14001 you get an internationally acknowledged brand that is recognized by organizations and companies worldwide. But the road to certification isn’t just easy, to be able to certify your environmental managemen

The aim of this study was to explore social workers' experiences and views of administrative tasks within the social services. Former research points to an explosion of administrative tasks for professions such as social workers, doctors and teachers, due to governance reforms and cutbacks in the welfare sector resulting in fewer assistants and secretaries. For this study, ethnographic fieldwo

In an attempt to at the same time introduce new technology into the existing public transport network, investigate the impact of this technology on street space in cities and present a solution to the problem with congestion in dense city centers a model is introduced. This model demonstrates one way to implement autonomous vehicles in the public transport network in dense city centers. The result

Due to an increasing ease of access to social media outlets, more tourists than ever are able to share their comments, images and videos of travel experiences. As such this user generated content is said to have more of an impact than professionally produced content on the decisions of prospective travellers. On this basis the major objective of this study is to identify the overall perspectives h

Abstract: Previous research has found car-sharing schemes to have great potential, internationally and locally, to reduce greenhouse gas emissions from the personal transport sector, and contain significant locally bounded advantages with implications for improved urban sustainable mobility and more efficient land-use. The aim of the paper is to explore how and why shared mobility services, specif

För att uppnå de nationella klimatmålen har energieffektivisering vid renovering av flerbostadshus uppmärksammats som ett strategiskt område. Dock väljer många fastighetsägare bort investeringar i energieffektiviserande åtgärder till förmån för projekt som anses vara mer lönsamma. Därmed är det av intresse att undersöka hur fastighetsägarna motiverar sina val vid investeringar i energieffektiviser