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Ten years of treating necrotizing fasciitis.
Perfectionism and sense of coherence among patients with eating disorders.
Background: There is a substantial body of research on eating disorders and perfectionism. Also there are several studies on eating disorders and sense of coherence (SOC), but studies regarding all three subjects are sparse. Perfectionism and the degree of SOC are considered central and aggravating aspects of psychiatric conditions, not least in relation to eating disorders. Aims: The present stud
Predictive markers of abdominal aortic stiffness measured by echo-tracking in subjects with varying insulin sensitivity.
Arterial stiffness is influenced by advancing age and vascular disease and is an independent risk factor for cardiovascular events and death. Using ultrasound measurements, arterial stiffness in a specific arterial segment can be assessed. The aim of this observational study was to explore the prospective and cross-sectional associations between arterial stiffness measured by ultrasound locally in
Deschampsia cespitosa and soil acidification: general and trait-specific responses to acid and aluminium stress in a solution experiment
Cocaine- and amphetamine-regulated transcript is expressed in adipocytes and regulate lipid- and glucose homeostasis.
Cocaine- and amphetamine-regulated transcript (CART) is a regulatory peptide expressed in the nervous system and in endocrine cells, e.g. in pancreatic islets. CART deficient mice exhibit islet dysfunction, impaired insulin secretion and increased body weight. A mutation in the CART gene in humans is associated with reduced metabolic rate, obesity and diabetes. Furthermore, CART is upregulated in
Characteristics of medication errors with parenteral cytotoxic drugs.
Systemic lupus erythematosus and cardiac risk factors: medical record documentation and patient adherence
This study explores patients' knowledge of cardiac risk factors (CRFs), analyses how information and advice about CRFs are documented in clinical practice, and assesses patient adherence to received instructions to decrease CRFs. Systemic lupus erythematosus (SLE) patients with >= 4 ACR criteria participated through completing a validated cardiovascular health questionnaire (CHQ). Kappa statistics
Family History of Myocardial Infarction Increases Risk of Renal Dysfunction in Middle Age.
Background/Aims: Chronic kidney disease (CKD) is common in the general population, may lead to end-stage renal disease, and is most frequently found among males. Familial clustering of kidney diseases has been observed. We aimed to study a potential association between the family history of myocardial infarction (MI) and renal dysfunction. Methods: 22,297 males and 10,828 females, aged 33-60 years
Associations between cadmium exposure and circulating levels of sex hormones in postmenopausal women.
Recent epidemiological as well as in vivo and in vitro studies collectively suggest that the metalloestrogen cadmium (Cd) could be a potential risk factor for hormone-related cancers in particularly breast cancer. Assessment of the association between Cd exposure and levels of endogenous sex hormones is of pivotal importance, as increased levels of such have been associated with a higher risk of b
Oxidized limonene and oxidized linalool - concomitant contact allergy to common fragrance terpenes.
BACKGROUND: Limonene and linalool are common fragrance terpenes. Both oxidized R-limonene and oxidized linalool have recently been patch tested in an international setting, showing contact allergy in 5.2% and 6.9% of dermatitis patients, respectively. OBJECTIVE: To investigate concomitant reactions between oxidized R-limonene and oxidized linalool in consecutive dermatitis patients. METHODS: Ox
pH preferences of red-listed gasteromycetes in calcareous sandy grasslands: Implications for conservation and restoration
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Blood pressure is a heritable trait(1) influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (>= 140 mm Hg systolic blood pressure or >= 90 mm Hg diastolic blood pressure)(2). Even small increments in blood pressure are associated with an increased risk of cardiovascular events(3). This genome-wide association study o
Behavioral correlates of changes in hippocampal gray matter structure during acquisition of foreign vocabulary.
Storm water quality of first flush urban runoff in relation to different traffic characteristics
Hemorrhage after ischemic stroke - relation to age and previous hemorrhage in a nationwide cohort of 58 868 patients
Habitat structure and juvenile fish ontogeny shape zooplankton spring dynamics
Macrophytes in shallow lakes have the potential to alter fish-zooplankton interactions considerably. How far predation effects by newly hatched fish (0+ fish) on zooplankton are influenced by different types of aquatic vegetation, and how effects change during the first weeks of fish ontogeny remains, however, less clear. In order to address these issues, we examined the predation effects of 0+ fi
Understanding Computer Users With Tetraplegia: Survey of Assistive Technology Users
An online survey in the form of a questionnaire was conducted to obtain the opinion of computer users with tetraplegia on their current computer interfaces and to assess desirable applications for future independent control using assistive devices. The survey included questions related to information about the respondents' injury/disease, everyday activities and social life, electronic devices and
Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes.
Lack or dysfunction of insulin producing β cells results in the development of type 1 and type 2 diabetes mellitus, respectively. Insulin secretion is controlled by metabolic stimuli (glucose, fatty acids), but also by monoamine neurotransmitters, like dopamine, serotonin, and norepinephrine. Intracellular monoamine levels are controlled by monoamine oxidases (Mao) A and B. Here we show that MaoA
MiR-184 regulates pancreatic β-cell function according to glucose metabolism.
In response to fasting or hyperglycemia, the pancreatic β-cell alters its output of secreted insulin; however the pathways governing this adaptive response are not entirely established. While the precise role of microRNAs (miRNAs) is also unclear, a recurring theme emphasizes their function in cellular stress responses. We recently showed that miR-184, an abundant miRNA in the β-cell, regulates co