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Contact sensitization to calocephalin, a sesquiterpene lactone of the guaianolide type from cushion bush (Leucophyta brownii, Compositae)

BackgroundCushion bush [Leucophyta brownii Cass.=Calocephalus brownii (Cass.) F. Muell.] is an Australian Compositae shrub that has been introduced into Scandinavia as a pot plant. The first case of sensitization occurred in a gardener, and the main allergen was identified as the guaianolide calocephalin. ObjectiveTo present the identification of the main allergen, and to assess the prevalence of

Shaping nursing home mealtimes

A number of studies stress the importance of positive mealtime experiences for nursing home residents. However, the components that comprise an ideal nursing home meal remain unclear, reflecting the ambiguity of whether nursing homes should be framed as institutions, domestic settings or a type of hotel. In this study, nursing home meals were viewed as situations that the involved parties could co

Diagnosis and treatment of heart failure in primary health care among elderly patients with non-insulin-dependent diabetes mellitus, with special reference to use of echocardiography

Objective-The aim of the present study was to describe how the diagnosis of heart failure (HF) was assessed, aetiology and management in elderly patients with non-insulin-dependent diabetes mellitus (NIDDM) in primary health care, with special reference to use of echocardiography. Design-Descriptive retrospective investigation. Setting-Ronneby and Karlskrona communities, both situated on the Swedi

Doing Loyalty: Defense Lawyers' Subtle Dramas in the Courtroom

The courtroom work of defense lawyers has received surprisingly little sociological attention. What does a defense lawyer actually do in court? How do defense lawyers represent their client beyond the hard paragraphs of the law? By studying this phenomenon in a context where the scope for expressive gestures is limited, it is possible to gain a greater understanding into the often subtle ways in w

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

Aging associates with impaired pancreatic islet function and increased type 2 diabetes (T2D) risk. Here we examine whether age-related epigenetic changes affect human islet function and if blood-based epigenetic biomarkers reflect these changes and associate with future T2D. We analyse DNA methylation genome-wide in islets from 87 non-diabetic donors, aged 26-74 years. Aging associates with increa

The initial evaluation of an Internet-based support system for audiologists and first-time hearing aid clients

Objectives: Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and flexible technological platforms are also possible. The present study aimed to evaluate the clinical application of an Internet-based support system for audiologists and their first-time hearing aid clients. Design: An Internet-

Managing nature in the home garden

Despite their rootedness, plants do move and are moved between different places in the garden, and from one garden to another. In many private gardens there are plants with a history, and owners who tell stories about how they were brought in from a different location, for example from an old relative or from a journey. These plants are often regarded as relics or souvenirs, and receive special at

Increased Levels of Copeptin, a Surrogate Marker of Arginine Vasopressin, Are Associated with an Increased Risk of Chronic Kidney Disease in a General Population

Background: Our aim was to test if plasma copeptin, a stable surrogate marker of arginine vasopressin, predicts decline of glomerular filtration rate (GFR) and risk of chronic kidney disease (CKD). Methods: We measured copeptin and renal function at the Malmö Diet and Cancer Cardiovascular Cohort baseline exam and reassessed renal function after a follow-up time of 16.6 ± 1.5 years (n = 3,186). Fu

Potential Influence of Diet on Bomb-Pulse Dating of Human Plaque Samples

The radiocarbon concentration of different atherosclerotic plaque fragments obtained from 20 patients in Portugal, operated in 2000-2001, has been measured in order to define the year of plaque formation. A difference of 1.8-15 yr was observed, with the mean and median both 9 yr, between the bomb-pulse date estimated with the CALIBomb software and the operation date. Stable isotope (delta C-13 and