Objective(s): Nitrite, a nitric oxide (NO) donor, increases insulin secretion from pancreatic islets and has positive metabolic effects in type 2 diabetes (T2D). Here, we test the hypothesis of whether nitrite-induced insulin secretion is due to blunting of diabetes-induced oxidative stress in the islets. Materials and Methods: T2D was created in male rats using a combination of streptozotocin at

Motivation in simultaneous L2 learning situations is an area of research largely overlooked and studies from contexts where people are engaged in learning more than one L2 are rare. In their large-scale Hungarian research, Dornyei, Csizer and Nemeth found that pupils' positive attitudes to one L2 could cause interferences with attitudes to others, with English being the greatest source of such int

How does elite communication influence affective polarization between partisan groups? Drawing on the literature on partisan source cues, we expect that communication from in- or outgroup party representatives will increase affective polarization. We argue that polarized social identities are reinforced by partisan source cues, which bias perceptions of elite communication and result in increased

Kan framtidens shoppingupplevelse redan ha varit här? Ja mycket av det som av både upplevelse- och hållbarhetsskäl anses tillhöra framtidens konsumtion dominerade butikslokalerna i svenska städer för hundra år sedan. Det såldes livsmedel i lösvikt, man behövde handla dagligen eftersom ingen hade kylskåp hemma och det fanns många verkstäder och skräddare där man beställde precis det man behövde (oc

Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and ter

Children’s in-session involvement in child and family therapies correlates with both positive and negative treatment outcomes. Thus, it is important to gain a better understanding of the clinical practices that facilitate children’s involvement in therapy sessions so that practitioners can employ them with greater precision. To address this need, we conducted a study to answer the following questi

Mycotoxins have been hypothesized to contribute to a diversity of adverse health effects in humans, even at low concentrations. Certain mycotoxins are established human carcinogens, whereas for others research suggests potential carcinogenic effects. The aim of this study was to determine the association between dietary exposure to mycotoxins and hepatobiliary cancers in the European Prospective I

Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive heart rate elevation upon standing or head-up tilt, in the absence of orthostatic hypotension. This debilitating condition affects primarily young to middle-aged individuals, particularly women, and substantially influences quality of life. The main presenting symptoms are lightheadedness, palpitations,

The increased electrification of society and the development of smart grids are often seenas central in the transition towards a more sustainable and secure energy system and necessaryto address the challenges of increasing energy demand and limited resources. Thereare many visions and ideas on what a smart grid is or could be. While most research relatedto environmental impacts on the smart grid

Background: Timely treatment of acute allergic reactions (AARs) is important to minimize reaction severity. Corticosteroid tablets dissolved in water are commonly used in mainstay treatment. A new oral film that dissolves on the tongue provides a faster and less cumbersome alternative to tablets for corticosteroid administration during AARs. This study evaluated patients' preferences for attribute

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer with a 5-year survival rate of less than 1-2%. Early onset pancreatic cancer (EOPC), i.e. patients below 50 years of age, is infrequently described. The present study aimed to determine the epidemiology, demographic incidence and prognosis of EOPC and to identify the characteristics that might distin

Housing provisions in the Western world, Australia included, are characterised by several challenges. New residential typologies are needed to cope with, for example, environmental and economic considerations of land use, escalating construction cost, and the lack of affordable housing. Urban form determines measures of density. It also spurs our common imaginaries of urban life. Hence,to calibrat

The global energy transition is not merely a technological shift toward renewable energy but also a transformation of power structures, agency, and governance. As nations and cities implement sustainable energy solutions, both traditional energy actors and new entrants are reshaping participation in the energy sector. Within this evolving context, the smart grid emerges as an arena where these dyn

The aim of this study was to add knowledge of the longitudinal associations between gaming and emotional closeness between parents and their children. We hypothesized that parent–child emotional closeness was linked to less gaming activity over time and that more gaming activity was linked to less parent–child emotional closeness over time. We also tested the moderating effect of child gender on t

Hybridization allows adaptations to be shared among lineages and may trigger the evolution of new species1,2. However, convincing examples of homoploid hybrid speciation remain rare because it is challenging to demonstrate that hybridization was crucial in generating reproductive isolation3. Here we combine population genomic analysis with quantitative trait locus mapping of species-specific trait