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“How Far Is the Closest Bus Stop?” : An Evaluation of Self-Reported versus GIS-Computed Distance to the Bus among Older People and Factors Influencing Their Perception of Distance
Previous research showed that living closer to bus stops could be a factor in promoting a healthy and active lifestyle. However, most of the studies relied on self-reported measures of distance, which might be affected by several confounders. In this study, self-reported distances among study participants were compared to actual ones, computed by the use of GIS (Geographic Information System) tech
Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase
One of the hallmarks of type 1 but also type 2 diabetes is pancreatic islet inflammation, associated with altered pancreatic islet function and structure, if unresolved. IL-1β is a proinflammatory cytokine which detrimentally affects β-cell function. In the course of diabetes, complement components, including the central complement protein C3, are deregulated. Previously, we reported high C3 expre
The importance of recurring public transport delays for accessibility and mode choice
On the Digital Front-Line : Far-Right Memory Work in Baltic, Central, and East European Online Spaces
This anthology explores the memory work performed by Baltic and Central and East European far-right actors in the online space. Situated at the crossroads between memory studies, far-right studies, and media studies, the volume’s seven chapters show how a wide range of far-right actors, from small movements to major parties, have exploited digital communication technologies in order to establish t
Using Novel Molecular-Level Chemical Composition Observations of High Arctic Organic Aerosol for Predictions of Cloud Condensation Nuclei
Predictions of cloud droplet activation in the late summertime (September) central Arctic Ocean are made using κ-Kohler theory with novel observations of the aerosol chemical composition from a high-resolution time-of-flight chemical ionization mass spectrometer with a filter inlet for gases and aerosols (FIGAERO-CIMS) and an aerosol mass spectrometer (AMS), deployed during the Arctic Ocean 2018 e
A Multi-Stakeholder Perspective on Barriers to a Fossil-Free Urban Freight System
The purpose of this study is to provide a system perspective on the barriers to the development of a fossil-free and thus more sustainable urban freight system and to provide insights regarding these barriers and how they impede progress. The system perspective complements earlier research, where barriers were identified in delimited parts of freight systems. Here, the urban freight system in a Sw
Cryo-EM structure supports a role of AQP7 as a junction protein
Aquaglyceroporin 7 (AQP7) facilitates glycerol flux across the plasma membrane with a critical physiological role linked to metabolism, obesity, and associated diseases. Here, we present the single-particle cryo-EM structure of AQP7 determined at 2.55 Å resolution adopting two adhering tetramers, stabilized by extracellularly exposed loops, in a configuration like that of the well-characterized in
Consumer Trust and Platformised Retail Personalisation
As retail is becoming increasingly digitised in its operation and consumer relationships, much faith is put into automation, prediction and insights drawn from consumer data to shape consumer experiences and expectations. Under the umbrella of data-collection and artificial intelligence (AI), this chapter studies the role of consumer trust in retail personalisation. We draw empirical insights from
Inhaled ciclesonide in adults hospitalised with COVID-19 : a randomised controlled open-label trial (HALT COVID-19)
Saving the World? How CSR Practitioners Live Their Calling by Constructing Different Types of Purpose in Three Occupational Stages
Much attention in the meaningful work literature has been devoted to calling as an orientation toward work characterized by a strong sense of purpose and a prosocial motivation beyond self-gain. Nonetheless, debate remains as to whether individuals change or maintain their calling, and especially whether they live their calling differently in different occupational stages. In this article, we resp
Biogeographical variation in antimicrobial resistance in rivers is influenced by agriculture and is spread through bacteriophages
Antibiotic resistance is currently an extensive medical challenge worldwide, with global numbers increasing steadily. Recent data have highlighted wastewater treatment plants as a reservoir of resistance genes. The impact of these findings for human health can best be summarized using a One Health concept. However, the molecular mechanisms impacting resistance spread have not been carefully evalua
Airspace Dimension Assessment with Nanoparticles (AiDA) in Comparison to Established Pulmonary Function Tests
Background: Airspace Dimensions Assessment with nanoparticles (AiDA) is a new method for non-invasive measurement of pulmonary distal airspaces. The aim of this study was to compare AiDA measurements with other pulmonary function variables to better understand the potential of AiDA in a clinical context. Methods: AiDA measurements and pulmonary function tests were performed in 695 subjects as part
Adverse childhood experiences do not moderate the association between aggressive antisocial behavior and general disinhibition in a forensic psychiatric inpatient sample
Adverse childhood experiences (ACE) and high levels of disinhibition have been associated with a variety of negative outcomes such as aggressive antisocial behavior (AAB). However, forensic psychiatric populations remain an understudied group in this field of research. This study aimed to fill that gap by investigating associations between ACE, AAB, and disinhibition in a forensic psychiatric samp
Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer : Case-control study
Objective: To determine the relation between concentrations of prostate specific antigen at age 60 and subsequent diagnosis of clinically relevant prostate cancer in an unscreened population to evaluate whether screening for prostate cancer and chemoprevention could be stratified by risk. Design: Case-control study with 1:3 matching nested within a highly representative population based cohort stu
The Stressful Memory Assessment Checklist for the Intensive Care Unit (SMAC-ICU) : Development and Testing
Stressful or traumatic memories of an intensive care stay may lead to long-term psychological morbidity. Memory assessment is therefore essential to aid in the patients’ recovery process. Acknowledging the large cohort of post ICU patients during the SARS-CoV-2 pandemic, a simple tool for the evaluation of ICU memories is needed. The aim of this study was, therefore, to develop and test the validi
Emergence and institutionalization of interorganizational coordination structures in crises
Crises often reveal a mismatch between organizational and problem structures, demanding interorganizational coordination or new organizational solutions. Much is known about functions and roles of such organizational solutions, but less about the processes underlying them. This study investigates the processes behind the emergence and institutionalization of organizational solutions to meet new co
The secondary bile acid isoursodeoxycholate correlates with post-prandial lipemia, inflammation, and appetite and changes post-bariatric surgery
Primary and secondary bile acids (BAs) influence metabolism and inflammation, and the gut microbiome modulates levels of BAs. We systematically explore the host genetic, gut microbial, and habitual dietary contribution to a panel of 19 serum and 15 stool BAs in two population-based cohorts (TwinsUK, n = 2,382; ZOE PREDICT-1, n = 327) and assess changes post-bariatric surgery and after nutritional