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Implementation of the Trade Secrets Directive into National Law: Portugal and Spain

The protection of trade secrets in Portugal and Spain has been derived from general legal principles (of Civil Law, Penal Law and Unfair Marketing Law). This chapter on implementation of the Trade Secrets Directive (TS Directive) in Portugal and Spain presents the traditional views and positions and the implementation of the TS Directive into the respective national legal orders.In Portugal, imple

Automation of building permission by integration of BIM and geospatial data

The building permission process is to a large extent an analogue process where much information is handled in paper format or as pdf files. With the ongoing digitalisation in society, there is a potential to automate this process by integrating Building Information Models (BIM) of planned buildings and geospatial data to check if a building conforms to the building permission regulations. In this

Re-evaluation of HER2 status in 606 breast cancers—gene protein assay on tissue microarrays versus routine pathological assessment

Human epidermal growth factor receptor 2 (HER2) status in breast cancer is routinely determined through immunohistochemistry (IHC) and/or in situ hybridisation (ISH) performed on whole tissue sections (WS). The purpose was to evaluate whether a gene protein assay (GPA) combining IHC with ISH, performed on breast cancer tissue microarray (TMA), is suitable for large-scale retrospective HER2 status

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Det er kjent fra før at langdistansebinding av refleksive pronomen forekommeri norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevdaat langdistanse binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelenargumenterer jeg for at langdistansebinding i norsk alltid er logoforisk,og at det samme gjelder for mellomdistansebinding. Det er bare lokal bindingsom Det er kjent fra før at langdistansebinding av refleksive pronomen forekommer i norsk. Fenomenet har blitt kobla til logoforisitet, men det har også blitt hevda at langdistanse­binding er mulig i visse ikke-logoforiske kontekster. I denne artikkelen argumenterer jeg for at langdistansebinding i norsk alltid er logoforisk, og at det samme gjelder for mellomdistansebinding. Det er bare lokal binding

Less-well known functions of cyclin/CDK complexes

Cyclin-dependent kinases (CDKs) are activated by cyclins, which play important roles in dictating the actions of CDK/cyclin complexes. Cyclin binding influences the substrate specificity of these complexes in addition to their susceptibility to inhibition or degradation. CDK/cyclin complexes are best known to promote cell cycle progression in the mitotic cell cycle but are also crucial for importa

Internationally adopted children with and without a cleft lip and palate showed no differences in language ability at school-age

Aim: The aim of this study was to investigate language ability in internationally adopted children aged 7-8 years with and without a unilateral cleft lip and palate. Methods: We compared 27 internationally adopted children with a unilateral cleft lip and palate, adopted from China, with a group of 29 children without a cleft lip and palate, adopted from different countries. Participants were recru

Likelihood of admission to hospital from the emergency department is not universally associated with hospital bed occupancy at the time of admission

Background: The decision to admit into the hospital from the emergency department (ED) is considered to be important and challenging. The aim was to assess whether previously published results suggesting an association between hospital bed occupancy and likelihood of hospital admission from the ED can be reproduced in a different study population. Methods: A retrospective cohort study of attendanc

Cancer and Risk of COVID-19 Through a General Community Survey

Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID-19) and adverse outcomes. However, evidence from large population-based studies examining whether cancer and cancer-related therapy exacerbates the risk of COVID-19 infection is still limited. Data were collected from the COVID Symptom Study smartphone application since March 29 through May 8, 2020. Among 23,266 partic

A novel function for CDK2 activity at meiotic crossover sites

Genetic diversity in offspring is induced by meiotic recombination, which is initiated between homologs at >200 sites originating from meiotic double-strand breaks (DSBs). Of this initial pool, only 1-2 DSBs per homolog pair will be designated to form meiotic crossovers (COs), where reciprocal genetic exchange occurs between parental chromosomes. Cyclin-dependent kinase 2 (CDK2) is known to locali

Attributional change and common-sense knowledge

The paper reports a study of change in causal explanations in therapeutic conversations. It shows how attribution of thoughts, feelings and behaviours which are experienced as problematic, e.g. embarrassing, awkward, absurd or painful, is changed from internal to more external. Namely, analysis focuses on how dispositional attribution – attributing problematic thoughts, feelings and behaviours to