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Communicating the Implementation of Open Notes to Health Care Professionals : Mixed Methods Study

BACKGROUND: The literature on how to communicate reform in organizations has mainly focused on levels of hierarchy and has largely ignored the variety of professions that may be found within an organization. In this study, we focus on the relationship between media type and professional responses.OBJECTIVE: The objective of this study was to investigate whether and how belonging to a profession in

Everyday influence - Democracy when health and social care are part of everyday life

This article contributes to ongoing discussions about frailty and vulnerability in critical gerontology by asserting that possibilities to engage and enact influence in everyday life situations is a crucial dimension of democracy in later life. We discuss how democracy in this sense can be threatened for older persons for whom health and social care services are needed, following from the labellin

Associations between off-label low-dose olanzapine or quetiapine and cardiometabolic mortality

Olanzapine and quetiapine are routinely used off-label at lower doses, though it remains unclear whether treatment is associated with mortality. Here, we examined the associations between low-dose olanzapine/quetiapine, defined as 5 mg/day of olanzapine equivalents (OE) with cardiometabolic mortality in a population-based, longitudinal cohort of individuals who sought specialized psychiatric servi

Activatable MRI probes for the specific detection of bacteria

Activatable fluorescent probes have been successfully used as molecular tools for biomedical research in the last decades. Fluorescent probes allow the detection of molecular events, providing an extraordinary platform for protein and cellular research. Nevertheless, most of the fluorescent probes reported are susceptible to interferences from endogenous fluorescence (background signal) and limite

Managing multiple medications and their packaging for older people in home care nursing : An interview study

Home care nurses assist older people in their daily living and well-being, including medication management. Medication management can be challenging for older people with functional constraints and several chronic conditions. This paper presents how home care nurses manage medications and their packaging for older people at their homes. This study followed an explorative qualitative research desig

Extracellular matrix: paving the way to the newest trends in atherosclerosis

PURPOSE OF REVIEW: The extracellular matrix (ECM) is critical for all aspects of vascular pathobiology. In vascular disease the balance of its structural components is shifted. In atherosclerotic plaques there is in fact a dynamic battle between stabilizing and proinflammatory responses. This review explores the most recent strides that have been made to detail the active role of the ECM - and its

Early onset externalizing behaviors among forensic psychiatric patients : Identification in child and adolescent psychiatric services

Forensic psychiatric patients constitute a heterogeneous patient group, with common comorbidity within the externalizing spectrum. Increased knowledge on early antecedents in the pathway to severe mental illness and criminality is needed. In this study, we investigated early onset externalizing behaviors in three groups of forensic psychiatric patients 1) patients without contact with child and ad

Decision-making fitness of methods to understand Sustainable Development Goal interactions

The integrated nature of the Sustainable Development Goals (SDGs) presents a challenge to implementing the 2030 Agenda. Analytical methods to support decision-makers are often developed without explicitly incorporating decision-makers’ views and experience. Here, we investigate whether existing methods are fit-for-purpose in supporting decision-makers at national and subnational levels. We identif

Entangled security logics: from the decision-makers’ discourses to the decision-takers’ interpretations of civil defence

Entangled logics, which attribute meaning to security, characterise the contemporary security field, bringing about broad comprehensions and ambiguous concepts. Civil defence has (re)surfaced as one such concept that is broadly conceived in the official discourses produced by decision-makers. Since security is ultimately enacted by practitioners, alias decision-takers, their interpretations of con

Promoting athero-protective immunity by vaccination with low density lipoprotein-derived antigens

Immune responses activated by LDL particles that have been trapped and oxidized in the arterial wall play an important role in atherosclerosis. Some of these immune responses are protective by facilitating the removal of pro-inflammatory and toxic lipid species formed as result of LDL oxidation. However, should these protective immune responses be insufficient, other more potent pro-inflammatory i

Glucocorticoid induced TNF receptor family-related protein (GITR) – A novel driver of atherosclerosis

Atherosclerosis is a lipid-driven, chronic inflammatory disease. In spite of efficient lipid lowering treatments, such as statins and PCSK9 inhibitors, patients, especially those with elevated inflammatory biomarkers, still have a significant residual cardiovascular disease risk. Novel drugs targeting inflammatory mediators are needed to further reduce this residual risk. Agonistic immune checkpoi

The Role of Patents and Licensing in the Governance of Human Genome Editing: A White Paper

On 12 July 2021 the World Health Organization (WHO) Expert Advisory Committee on Developing Global Standards for Governance and Oversight of Human Genome Editing published a set of reports entitled Human Genome Editing: A Framework for Governance and Recommendations. These reports provide valuable advice and recommendations on appropriate institutional, national and global governance mechanisms fo

Authors and Creative Users : Addressing the Conceptual Challenges of Digital Creativity to EU Copyright Law from the Perspective of the Author

To be an “author” might mean many different things, depending on the context in which the word is used. This thesis explores the EU copyright’s concept of author and how it relates to the everyday digital creativity on the Internet. It invites to consider what EU copyright law might look like if the digital creators which this thesis calls Creative Users were included in the legal system as “autho

Developing shared languages : The fundamentals of mutual learning and problem solving in transdisciplinary collaboration

This issue of the AILA Review focuses on transdisciplinarity as the key to developing shared languages in and across domains and professional settings. The relationship and collaboration between researchers and practitioners have long been discussed within and across applied sciences and theoretical disciplines, mainly in the framework of transdisciplinarity (see AILA Review 31, 2018, for a recent