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We have previously reported suggestive linkage to chromosome 5p13-q13 in type 1 diabetic families. ISL1, a transcription factor involved in pancreas development, maps to this region. Sequencing of the ISL1 gene in patients and control subjects identified seven single nucleotide polymorphisms (SNPs) and one microsatellite in noncoding regions. Four haplotypes formed by six of these SNPs and one mic
The most important issue in this dissertation will be a discussion concerning metal age flint use in Scania. Since flint tools from the Bronze and Iron Ages and Medieval times have rarely been examined, there are few general guidelines in typology or morphology. It is quite clear that conversions of existing Stone Age typological schemes are unsuitable when one intends to study the often simple an
OBJECTIVE: To determine the diagnostic value of metaiodobenzylguanidine (MIBG) scintigraphy compared with computed tomography (CT) for the localization of phaeochromocytomas in clinical practice. DESIGN: Retrospective comparison between MIBG scintigrams and CT for localization of phaeochromocytomas in all patients successively examined with MIBG scintigraphy in Malmo from 1984 until January 1997.
BACKGROUND: The clinically important Kidd (JK) blood group antigens are carried by the urea transporter in red cells. The rare Jk(a-b-) phenotype can be caused by homozygosity at the JK locus for a silent allele, JK: This phenotype has been recorded in many ethnic groups, but it is most abundant among people originating from the Polynesian Islands and Finland. The molecular basis for Jk(a-b-) is u
Objective Recent studies suggest an increased prevalence of obstetric complications in female carriers of hereditary or acquired thrombophilias. The aim of the study was to determine if carriership of the factor V (FV) Leiden mutation (activated protein C [APC] resistance) is higher in women who have had of placental abruption during pregnancy. Design A retrospective case-control study. Setting Un
It is well known that the effects of direct (lethal) predator-prey interactions propagate through food webs (the trophic cascade). However, in the present study we show for the first time that, parallel to the trophic cascade, there exists a behavioral cascade in the sense that behavioral responses, induced by the nonlethal presence of a top predator, are transmitted down the food chain over more
Background: Enhanced recovery program for pancreaticoduodenectomy have become standard care. Little is known about adherence rates and sustainability of the program, especially when pancreaticogastrostomy is used in reconstruction. The aim of this study was, therefore, to evaluate adherence rates and continued outcome, after implementation of an enhanced recovery program. Methods: Consecutive pati
In spite of substantial greenhouse gas emissions from photo-degradation of dissolved organic carbon (DOC), little is known about the variability in DOC photo-reactivity. It has been suggested that photo-reactivity depends on the degree of DOC pigmentation. However, recent evidence suggests that also non-colored fractions can be photo-reactive. Furthermore photo-degradation processes interact with
Planktonic community respiration is an important carbon cycling process, typically quantified by converting measured values of dissolved oxygen consumption rates into carbondioxide production rates using a respiratory quotient of 1 (RQ = carbondioxide per oxygen by moles). However, the true variability in planktonic RQs between different aquatic ecosystems is poorly understood. We conducted in sit
