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Social workers strive to provide the best support to each client, making it crucial to consider not just group-level effects of interventions but also individual outcomes. While empirical evidence often stems from group-based analyses, these offer limited insights into individual change, which is key for tailoring interventions. The aim of this study is to highlight the importance of individual-le

Diabetic kidney disease (DKD) is the leading cause of end stage kidney failure worldwide, of which cellular insulin resistance is a major driver. Here, we study key human kidney cell types implicated in DKD (podocytes, glomerular endothelial, mesangial and proximal tubular cells) in insulin sensitive and resistant conditions, and perform simultaneous transcriptomics and proteomics for integrated a

Antimicrobial peptides (AMPs), particularly host defense peptides (HDPs), have gained recognition for their role in host defense mechanisms, but they have also shown potential as a promising anticancer, antiviral, antiparasitic, antifungal and immunomodulatory agent. Research studies in recent years have shown HDPs play a crucial role in endothelial cell function and biology. The function of endot

Increasing the share of travelers using public transport is one way to address environmental problems such as carbon dioxide emissions. Senior citizens represent an increasingly important group in this transition, as they are increasingly mobile and make up a large share of the population. In this paper, we investigate senior citizen's mobility decision-making, focusing on public transport. Throug

first_pageDownload PDFsettingsOrder Article ReprintsOpen AccessArticleDiagnostic Performance of Clinical and Routine Laboratory Data in Acute Mesenteric Arterial Occlusion—An International Multicenter Studyby Yasmin Soltanzadeh-Naderi 1ORCID,Annika Reintam Blaser 2,3ORCID,Martin Björck 2,4,Alexandre Nuzzo 5ORCID,Joel Starkopf 2,6,Alastair Forbes 2,Marko Murruste 2,6ORCID,Kadri Tamme 2,6ORCID,Peep

With care being increasingly present and offered for sale on markets consumers are more often asked to consider ethical questions. However, ethical consumption literature has not paid close attention to how the selling of different care offerings contributes to the ethicalisation of consumption. To illustrate and conceptualise this phenomenon, the present paper builds on an object-focused study of

Craft has been a steady adversary to the proliferation of industrialization. As an imaginary of embodied work, mainly driven by intrinsic motivation and by a strive for excellence, craft is increasingly re-emerging in discussions on improving current forms of work. A common theme across research on craft is its potential to address alienation as one of the main pathologies of modern work. We study

Insulin is packaged into secretory granules that depart the Golgi and undergo a maturation process that involves changes in the protein and lipid composition of the granules. Here, we show that insulin secretory granules form physical contacts with the endoplasmic reticulum and that the lipid exchange protein oxysterol-binding protein (OSBP) is recruited to these sites in a Ca2+-dependent manner.

Although we have learned much about how the brain fuels its functions over the last decades, there remains much still to discover in an organ that is so complex. This article lays out major gaps in our knowledge of interrelationships between brain metabolism and brain function, including biochemical, cellular, and subcellular aspects of functional metabolism and its imaging in adult brain, as well

Added insulation in cold attics can be an efficient and profitable energy efficiency measure. Simultaneously, added insulation increases the risk of a decreased temperature in the attic, thereby increasing the risk of high relative humidity and moisture damage. This paper collocates and reviews previous publications that deal with the impact of added insulation on attics as a renovation measure. T

Collective intelligence (CI) in demand-side management (DSM) can enhance the flexibility of urban energy systems. Extreme climates cause intensively high loads on the urban energy systems resulting in power outages. To avoid this, quick responses are needed from buildings to adjust their operation in favor of the grid. Most of the available approaches are computationally expensive. CI-DSM offers a

The well-publicized disinformation campaigns surrounding recent elections, pandemic vaccination adoption, as well as supply-chain disruptions and shortages have made historical problems of disinformation more apparent. When disinformation targets transportation infrastructure, supply chains can be disrupted, resulting in commodities shortages such as food and fuel, consequently jeopardizing the he

Aerosols and their interaction with clouds constitute the largest uncertainty in estimating the radiative forcing affecting the climate system. Secondary aerosol formation is responsible for a large fraction of the cloud condensation nuclei in the global atmosphere. Wetlands are important to the budgets of methane and carbon dioxide, but the potential role of wetlands in aerosol formation has not

In eukaryotes, iron-sulfur clusters are essential cofactors for numerous physiological processes, but these clusters are primarily biosynthesized in mitochondria. Previous studies suggest mitochondrial ABCB7-type exporters are involved in maturation of cytosolic iron-sulfur proteins. However, the molecular mechanism for how the ABCB7-type exporters participate in this process remains elusive. Here

EU law increasingly requires that the Member States establish independent administrative bodies in various fields. Examples include market supervision, non-discrimination, and data protection. This article addresses the realisation of such requirements in the five Nordic states. The West Nordic systems of Denmark, Iceland, and Norway feature a traditional hierarchic organisation of the administrat

What is the relationship between trust and the quality of political institutions in a society? According to an influential cultural perspective, social trust—the belief that most people can be trusted—is a value inculcated during individuals’ formative years, and remains fixed afterward. A second perspective holds that social trust reflects experiences throughout the life course, particularly inte