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Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and similar to 2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci
För att generalklausulen i den svenska lagstiftningen mot skatteflykt ska kunna tillämpas krävs det att skatteförmånen som uppstår strider mot lagstiftningens syfte. Vad detta innebär är inte fullständigt klarlagt av vare sig lagstiftaren eller av Högsta förvaltningsdomstolen. Lagens syftar till att domstolen ska göra en analog tolkning och dess rättssäkerhet har därför varit omdiskuterad. Syftet
Microsoft Word - MariaTonini_Slutseminar_Manuscript.docx Maria Tonini Ph.D. candidate Department of Gender Studies Lund University SAME SEX SEXUALITIES AND RECOGNITION IN CONTEMPORARY INDIA (working title) Manuscript prepared for the final seminar (“slutseminarium”) 28th October 2015 WORK IN PROGRESS NOT FOR CIRCULATION OR QUOTATION 2 INDEX 1. Introduction: Young people’s queer sexuality in contem
https://www.genus.lu.se/sites/genus.lu.se/files/mariatonini_slutseminar_manuscript.pdf - 2025-10-04
Cystic fibrosis-related diabetes mellitus (CFRD) is the most common non-pulmonary co-morbidity in cystic fibrosis (CF). CF is caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR), which leads to aberrant luminal fluid secretions in organs such as the lungs and pancreas. How dysfunctional CFTR leads to CFRD is still under debate. Both intrinsic effects of dysfu
Background: During the 21st century, diabetes mellitus (DM) and peripheral artery disease (PAD) have become global problems. It is estimated that 19-34% of individuals with DM will develop a foot ulcer during their lifetime, and many will be amputated.Aim:-To study dietary and lifestyle factors associated with prevention of PAD among individuals with DM. -To evaluate outcomes after vascular and en
Orientation towards application, transdisciplinarity and social distribution are prominent ideas when policy prescribes how to conduct research on complex, real-world issues. Issues dealt with in ageing research are both epistemologically complex and politically contentious. By using the metaphor of ‘travelling ideas,' we have followed these ideas on their journey into 17 approved grant proposals
The analysis of the verb phrase poses interesting problems. This paper suggests a binary solution where the auxiliary is treated as one constituent and the main verb complex as another. Auxiliaries are thus not treated as main verbs as was suggested by Ross 1967 (and followed in the first version of Referent Grammar, Sigurd 1987). The auxiliary may be lacking (latent, empty), in which case the mai
X-ray propagation-based imaging techniques are well established at synchrotron radiation and laboratory sources. However, most reconstruction algorithms for such image modalities, also known as phase-retrieval algorithms, have been developed specifically for one instrument by and for experts, making the development and diffusion of such techniques difficult. Here, PyPhase, a free and open-source p
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-ba
Objectives: The main goal of the COVIDENZA trial is to evaluate if inhibition of testosterone signalling by enzalutamide can improve the outcome of patients hospitalised for COVID-19. The hypothesis is based on the observation that the majority of patients in need of intensive care are male, and the connection between androgen receptor signalling and expression of TMPRSS2, an enzyme important for
Is the 'natural resource curse' destiny? Are different ways to link natural resources and economic development? Using two particular regions as case studies, this edited collection examines the divergent development paths of natural resource rich countries over the past two centuries. Bolivia, Chile and Peru are neighbour states with a common history and are globally known by their mining endowmen
