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Coffee is the most common drink in the world, second only to water. This makes caffeine, the ingredient of coffee known for its wakefulness-promoting effects, one of the most used psychoactive substances. The psychoactive property of caffeine is well-characterized, and entails its interaction with the adenosine receptors, involved in sleep regulation. While studies have shown a deleterious immedia
Formulating Research Problems addresses one of the most critical yet often overlooked aspects of research: how to define and frame the problem at the heart of a study. While most research methods texts devote only a few pages to this question, Johan Alvehus offers a dedicated, accessible, and practical guide that helps students move beyond vague topics toward the development of clear, rigorous, an
This book proposes the study of norms as a method of explaining human choice and behaviour by introducing a new scientific perspective.The science of norms may here be broadly understood as a social science which includes elements from both the behavioural and legal sciences. It is given that a science of norms is not normative in the sense of prescribing what is right or wrong in various situatio
Purpose: This paper investigates how farm advisers can develop their practices beyond facilitating farmers’ legal compliance to mediate between farmers’ and regulatory officials’ knowledge and experience of implementing farm-level legal regulation. Design/methodology/approach: Building on theories of knowledge types and Communities of Practice (CoP), the paper employs a qualitative research design
The purpose of this essay is to examine the concept of competence within the social services. More specifically it aims to find out how the social workers themselves look upon their own competence in social investigations concerning children. As the study was based on focus groups the main questions were vague at the beginning and were cleared later on during the group sessions. In three focus gr
It is claimed by several Western experts that the citizens are loosing confidence in their politicians. If true, it poses a serious threat to the legitimacy of the decisions made by politicians. The answer to this claimed lack of trust could be found in the politician role, because this role is the link between the mass and the political institutions. Politicians act as the representatives of the
Internet has made information more easy to get, but also more difficult to retrieve. There is a need for information retrieval systems that assure accurate, reliable and up to date information. Quite a number of both commercial and non commercial search services has been developed on the Internet. We have made a qualitative study of one for-pay product in particular, NetS k, produced by BTJ (Bibli
Learning a language is a creative process. It involves novelty and imagination. While curiosity can be highly beneficial, research is limited. Studies so far conducted have explored epistemic curiosity as a trait-like disposition. In contrast, the current study focuses on perceptual curiosity (PC). PC is a situational response evoked by novelty, complexity and ambiguities in sensory stimulation. P
The current classification of diabetes had its genesis over 85 years ago, when individuals with diabetes were first subclassified into insulin sensitive and insulin insensitive states based on the response to an oral glucose tolerance test. About 35 years later, the contemporary classifications of type 1 and type 2 diabetes were coined. Today's evidence, however, suggests that multiple etiologic a
In mouse early pachytene spermatocytes, the X and Y chromosomes undergo rapid non-homologous (NH) synapsis and desynapsis, but the functional significance remains unknown. Here, we report that pachynema-specific knockout of Speedy A (SpdyA) from telomeres caused persistent Y-X NH synapsis, with the entire Y axis synapsed onto the X axis. This persistent Y-X NH synapsis did not interrupt meiotic se
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer with a 5-year survival rate of less than 1-2%. Early onset pancreatic cancer (EOPC), i.e. patients below 50 years of age, is infrequently described. The present study aimed to determine the epidemiology, demographic incidence and prognosis of EOPC and to identify the characteristics that might distin
The research presented here explores the nuances of data collection and sharing via digital platforms in everyday CrossFit coaching practice. There is a growing body of work on data and digital platforms in CrossFit, though currently there is a lack of research on the role of coaches in these processes. Empirically grounding the digital fitness practices of CrossFit coaching is essential for our u
Acute-phase inhibition of the pro-inflammatory alarmin S100A8/A9 improves cardiac function post-myocardial infarction (MI), but the mechanisms underlying the long-term benefits of this short-term treatment remain to be elucidated. Here, we assessed the effects of S100A8/A9 blockade with the small-molecule inhibitor ABR-238901 on myocardial neovascularization in mice with induced MI. The treatment
Increased global migration to welfare states puts pressure on successful integration. Successful integration is broadly associated with entry into the labour market. Therefore, integration is measured through employment. Attempts to increase migrant involvement in the labour market are often made by street-level organisations, where interactions between individuals from the private and/or public s
