We present and test a model of the accumulation of plant competences. Fundamentally, the cumulative model consists of three building blocks: production competences, supply chain competences, and development competences, which are added successively. First, the basic production competence bundle comprises manufacturing, technical maintenance, and process development. Second, supply chain competence

For many years, a connection between circadian clocks and cancer has been postulated. Here we describe an unexpected function for the circadian repressor CRY2 as a component of an FBXL3-containing E3 ligase that recruits T58-phosphorylated c-MYC for ubiquitylation. c-MYC is a critical regulator of cell proliferation; T58 is central in a phosphodegron long recognized as a hotspot for mutation in ca

In this paper, we investigate the annotation projection of semantic units in a practical setting. Previous approaches have focused on using parallel corpora for semantic transfer. We evaluate an alternative approach using loosely parallel corpora that does not require the corpora to be exact translations of each other. We developed a method that transfers semantic annotations from one language to

In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood pressure SNPs and 53 rare variants in genome-wide association studies of systolic, diastolic and pulse pressure in up to 776,078 participants from the Million Veteran Program

The latest edition of the Swiss standard SIA181(2006) Protection against noise in Buildings [1], introduces a new methodology regarding the tests to be performed in new constructions for noise induced by human using service equipment in bathroom and kitchen. In this method, a specific pendling hammer has been developed especially for evaluating the decoupling efficiency of service equipment. The g

A growing body of research highlights how the Internet and social media offer new platforms for advocacy. This article contributes to the debates on digital advocacy by combining interest group and social media studies and present the notions of digital access politics, digital information politics, and digital protest politics for a comprehensive analysis of digital advocacy. Based on a netnograp

BACKGROUND: Studies have shown that patients with depression have higher rates of coronary heart disease (CHD) than people in the general population. However, large-scale population-based data on incidence rates of CHD in people with depression are needed. This study analyzed whether hospitalization for depression predicts CHD in men and women after accounting for socioeconomic status and geograph