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Objective: Smooth muscle cells contribute significantly to lipid-laden foam cells in atherosclerotic plaques. However, the underlying mechanisms transforming smooth muscle cells into foam cells are poorly understood. The purpose of this study was to gain insight into the molecular mechanisms regulating smooth muscle foam cell formation. Approach and results: Using human coronary artery smooth musc
Management of asymptomatic carotid disease continues to challenge medical practice and present evidence is often conflicting. Stroke is a significant burden in Public Health and 11% to 15% appear as first neurologic event associated with asymptomatic carotid stenosis. Randomized trials provided support for Guidelines and Recommendations to intervene on asymptomatic stenosis, but at a known cost of
Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased organ donors aged 1–81 years. The transcriptomes of the extracted islets were analysed using Ion AmpliSeq sequencing. 346 genes that co-vary signific
The aim of this paper is to analyse the type of mobilities and subjects that are being promoted and constituted through bike-sharing systems. This is done through an analysis of the bike-sharing system in the city of Lund in Sweden. The analysis utilises Bacchi’s What is the Problem Represented to be? framework and develops it through adding a spatial perspective. Departing from a critical velomob
Over the last two decades, electrification has gained importance as a means to decarbonise the transport sector. As the number of Electric Vehicles (EVs) increases, it is important to consider broader system aspects as well, especially when deciding the type, coverage, size and location of the charging infrastructure required. This article proposes a new approach using agent-based simulations to a
This study assessed whether methods for capturing the pedestrian experience of outdoor lighting, previously evaluated in a full‐scale laboratory, were applicable in a real‐world setting. It applied an approach capturing the human response to outdoor lighting in a systematic way, by assessing perception, evaluation and behaviour in the lit environment. The study involved 81 participants from two ag
Moderate exercise is deemed beneficial for cognition due to increase in dopamine concentrations in the basal ganglia. Auditory white noise is beneficial for cognition, mainly for those with lower attentional ability, i.e. for those having lower tonic dopamine concentrations. For individuals with higher attention ability white noise can have a negative effect. In this thesis it was examined whether
ABSTRACT Author: Emelie Olsson Title: "It gets a bit twice, voluntarily and yet not voluntarily"- Social workers approach to support, control / coercion and repression in financial assistance and substance abuse Supervisor: Weddig Runquist Assessor: Mats Hilte The purpose of this study has been to examine and analyze the exercise of authority social workers in the social services for sub
Studiens syfte var att psykometriskt undersöka ett testverktyg för mätning av matematiskt problemlösningsförmåga. För detta syfte fick 273 elever i åk 2 göra det läsplattebaserade testet Klurisen vid två tillfällen och en svensk version av Iowa Test of Basic Skills, deltest Mathematical Problem Solving, benämnt IOWA, vid ett tillfälle. Studien fann att Klurisens deltest, A- och B-del hade otillräc
Syfte: Undersöka hur stor andel av de aktierekommendationer som utfärdas för svenska aktiebolag som visar sig vara goda råd, ett år efter publiceringsdatum. Vidare analyseras ifall det råder någon specifik skillnad mellan köp- och säljrekommendationer. Metod: Kvantitativ studie med deduktiv ansats. Insamlade aktierekommendationer analyseras för att beräkna en eventuell abnormal avkastning. Result
Larvae from the non-biting midge family Chironomidae have previously been demonstrated to be sensitive to environmental pollution in aquatic environments. Exposure to different contaminants has resulted in an increasing occurrence of deformities of the mouthparts in the larvae. Common pollutions which induce mouthpart deformitys are metals (such as Pb, Zn, Cd, Cu, Hg, Cr, Ni), pesticides and some
The aim of this study was to examine how home care workers are reasoning about and using their discretion in their work with elder people with alcohol problems. The two concepts responsibility and respect was used to understand the difficulty and dilemmas they encounter in their work with elderly with alcohol problems. The study was based on semi-structured interviews, combined with two vignettes,
The aim of this study is to create an understanding of how caregivers at nursing homes in both the public and the private sector working conditions manifests itself from an organization theory perspective. The aim of this paper is to describe and analyze how the caregivers in elder care experience their working conditions and if the experiences differ depending on whether they work in the public o
As the society gets more and more dependent on electrical energy, it is highly desirable to ensurepower supply at all times. In case of events of natural disasters, simple technical faults or human mistakes, any power system or a large part of it can suffer a blackout. An electrical shutdown is a crisis situation where recovery should happen as quickly as possible. During the restoration after the
