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Consumers’ value creating processes in distribution services for online shopping

Extended abstract Recent studies point at significant and ongoing technology induced changes in the retail landscape, creating new and interesting research avenues, new managerial challenges and a need to rethink existing business models (e.g., Burt and Sparks 2003; Kollmann et al., 2012; Sorescu et al., 2011). This paper aims at contributing to the literature concerning the managerial aspects th

Improvisation and the self: to listen to the other

To listen to the other: This phrase raises an incalculable number of issues. One of the central topics in teaching improvisation is learning how to listen to those with whom one plays, but in my experience the most difficult task is listening to the self. The point of listening to the other in performance is obviously not to completely give up the self, nor is it to become the other, but to attune

Combination of solar collectors and ground-source heat pump for small buildings

The combination of solar heat and ground-source heat pumps in dwellings gives opportunities for optimising the use of renewable energy sources and minimize the share of bought energy. Solar collectors in the system may give advantages for the operational conditions both for the solar collectors and for the heat pump. The aim of this project was to analyse different variables such as energy demand,

Advancing Basal Insulin Replacement in Type 2 Diabetes Inadequately Controlled With Insulin Glargine Plus Oral Agents: A Comparison of Adding Albiglutide, a Weekly GLP-1 Receptor Agonist, Versus Thrice-Daily Prandial Insulin Lispro.

GLP-1 receptor agonists may provide an alternative to prandial insulin for advancing basal insulin therapy. Harmony 6 was a randomized, open-label, active-controlled trial testing once-weekly albiglutide vs thrice-daily prandial insulin lispro as an add-on to titrated once-daily insulin glargine.RESEARCH DESIGN AND METHODS: Patients taking basal insulin (with or without oral agents) with HbA1c 7-1

Role of non-coding RNAs in pancreatic beta-cell development and physiology.

The progression of diabetes is accompanied by increasing demand to the beta-cells to produce and secrete more insulin, requiring complex beta-cell adaptations. Functionally-active and ubiquitous non-coding RNAs (ncRNAs) have the capacity to take part in such adaptations as they have been shown to be key regulatory molecules in various biological processes. In the pancreatic islets, the function of

Imaging apolipoprotein AI in vivo

Coronary disease risk increases inversely with high-density lipoprotein (HDL) level. The measurement of the biodistribution and clearance of HDL in vivo, however, has posed a technical challenge. This study presents an approach to the development of a lipoprotein MRI agent by linking gadolinium methanethiosulfonate (Gd[MTS-ADO3A]) to a selective cysteine mutation in position 55 of apo AI, the majo

Adiponutrin: A multimeric plasma protein.

The interest in adiponutrin stems from adiponutrin variant I148M, which is strongly associated to non-alcoholic fatty liver disease. Adiponutrin has to date been considered to be solely an intracellular protein, with a role in lipid metabolism in liver and adipose tissue. However, a physiologically relevant role for adiponutrin has not been found. The aim of this study was to investigate the prese

Quantifying the Family Frailty Effect in Infant and Child Mortality by Using Median Hazard Ratio (MHR)

Most microlevel studies in the social sciences have focused on the impact of different measured variables. While some studies have also dealt with unobserved variation, it has usually only been controlled for to perfect the estimates of the observables. In this article, the authors applied a modified version of a recently developed method designed to quantify the effect of unobserved variation in

A gluten free diet lowers NKG2D and ligand expression in BALB/c and NOD mice.

The interplay between diet and immune-parameters which could affect type 1 diabetes (T1D) pathogenesis is not sufficiently clarified. Intestinal upregulation of the activating receptor NKG2D(CD314) and its ligands is a hallmark of celiac disease (CD). However, the direct effect of gluten on NKG2D expression is not known. We studied, by FACS (lymphoid tissues) and RT-qPCR (intestine and pancreatic

Gardens benefit bees and enhance pollination in intensively managed farmland

The recent loss of pollinating insects and out-crossing plants in agricultural landscapes has raised concern for the maintenance of ecosystem services. Wild bees have been shown to benefit from garden habitats in urban and suburban areas. We investigated the effects of distance from garden habitats on wild bees and seed set of a native out-crossing plant Campanula persicifolia, in intensively mana

The middle Darriwilian (Ordovician) delta C-13 excursion (MDICE) discovered in the Yangtze Platform succession in China: implications of its first recorded occurrences outside Baltoscandia

The middle Darriwilian delta C-13 excursion (MDICE), one of the least known of the Ordovician delta C-13 excursions, has previously been recorded only from the Middle Ordovician of Baltoscandia. Analysis of many recently collected limestone samples from the Guniutan Formation at two Yangtze Platform localities show elevated delta C-13 values in the same biostratigraphic interval (Microzarkodina oz

Autoimmunity against INS-IGF2 expressed in human pancreatic islets.

Insulin is a major autoantigen in islet autoimmunity and progression to type 1 diabetes. It has been suggested that the insulin B-chain may be critical to insulin autoimmunity in type 1 diabetes. INS-IGF2 consists of the preproinsulin signal peptide, the insulin B-chain and eight amino acids of the C-peptide in addition to 138 amino acids from the IGF2 gene. We aimed to determine 1) expression of

Konkurrerande förseningsorsaker och entreprenörens rätt till tidsförlängning enligt AB 04

I ett entreprenadavtal regleras det normalt huruvida det är beställaren eller entreprenören som ska bära ansvaret för att en entreprenad försenats. En situation som mer sällan regleras är vem av parterna som ska bära risken om det föreligger konkurrerande förseningsorsaker. Avsikten med förevarande framställning är därför att analysera hur en domstol skulle bedöma en entreprenörs krav på tidsförlä

Characterization of a Zeeman Slower Designed for a 87 Sr Optical Clock

Mot ökad tidsnoggrannhet i Sverige Atomur baserade på mikrovågor är i dag den teknik som används för tidshållning. Snart kan detta komma att förändras i och med optiska klockor. Dessa klockor har bland annat potential att kunna förbättra satellitbaserade navigeringssystem som GPS och har en så hög noggrannhet att det öppnar upp nya möjligheter för forskning kring gravitation. En klocka är fundame

Låsta bevis: En nyckelfråga? - En studie av krypterat material som bevismedel i brottmål

Åtkomst till bevismaterial är avgörande för att förverkliga det straffrättsliga ansvaret. Idag är en stor del av detta bevismaterial digitalt och i syfte att skydda och hemlighålla sådan information används i allt större utsträckning kryptering. Kryptering, som enklast möjligt kan sägas utgöra den digitala versionen av att låsa in material i ett kassaskåp, innebär att man utan den särskilda dekrypBeing able to access evidence is crucial for the realisation of responsibility under criminal law. In today’s world, a large part of what can potentially be evidence is stored digitally. In order to protect and keep digital information confidential, encryption is becoming widespread. Encryption, put simply, can be said to be the digital version of locking material in a safe, and basically means th

God sed och riktade emissioner

En av de viktigaste aktörerna på aktiemarknaden är Aktiemarknadsnämnden (AMN). Även om nämndens formella kompetens är omfattande, ankommer det inte på nämnden att avgöra hur aktiebolagslagen (2005:551, ABL) ska tolkas. Trots detta är nämndens förhållningssätt till ABL ofta av stor betydelse för rättsläget, rörande riktade nyemissioner på den svenska aktiemarknaden. Uppsatsen diskuterar särskilt hu

Ett självklart offer? En intervjustudie av myndigheters samverkan gällande barn som bevittnat våld i nära relation

Denna studie undersöker samverkansprocessen mellan Socialtjänst, Polis- och Åklagarmyndighet i deras arbete med barn som bevittnat våld i nära relationer. Syftet är att skildra och problematisera samverkan beträffande barn som bevittnat våld och deras eventuella möjlighet till att uppnå status som offer. Även kvinnojourers uppfattning om myndigheternas arbete har undersökts. Materialet omfattar sj