Molekylär kunskap om tumörutveckling leder till allt fler målinriktade cancerbehandlingar.Heltäckande molekylär tumörkarakterisering ger möjlighet att undersöka samtliga behandlingsalternativ med en analys.Arbetsutskottet för solida tumörer inom Genomic Medicine Sweden samarbetar för att etablera regional och nationell infrastruktur för storskalig tumörsekvensering och kopplad dataanalys i sjukvårRapidly expanding knowledge of the molecular landscape of cancers has resulted in the implementation of an increasing number of specific therapies targeted at tumors with specific molecular aberrations. In response to this development, new tools for predictive testing for molecular targets need to be implemented in routine health care. To achieve robust future molecular diagnostic pathology, and e

Background: Thyroidectomy is a common surgical procedure performed worldwide. Postoperative complications can be life-threatening. Many efforts have been made during the last century to reduce the burden of postoperative complications, with remarkable achievements. However, there are still many patients suffering.Aims: the main aims of the first three studies were to understand risk factors for in

North Sámi has a class of derived verbs called sensive verbs. Descriptively, these verbs are formed by adding the suffix /ʃ/ to an adjectival or nominal base, and the resulting verb means ‘find [object] (too) ADJECTIVE/NOUN’. In this paper it is argued that the sensive verbs do not involve any psychological verb, and the suffix is not specified as “sensive” in the lexicon. Rather, the suffix is spNorth Sámi has a class of derived verbs called sensive verbs. Descriptively, these verbs are formed by adding the suffix /ʃ/ to an adjectival or nominal base, and the resulting verb means ‘find [object] (too) ADJECTIVE/NOUN’. In this paper it is argued that the sensive verbs do not involve any psychological verb, and the suffix is not specified as “sensive” in the lexicon. Rather, the suffix is sp

This paper investigates sustainability in retailing based on three different perspectives: i) the overall corporate management, ii) the development of an attractive product range, iii) the daily in-store management and activities. The purpose is to identify a set of main themes for each perspective, investigate contradictions and areas of conflict, and discuss how to bridge the perspectives. A qua

This chapter aims to discuss challenges related to governing in a digitalized era. In the public sector, digitalization and ICT solutions are regarded as a way to alleviate the burden of a sector under pressure. The suggested solutions are many, from computers making decisions to robots substituting teachers. Through digitalization resources can be freed up and public service provision be delivere

Exporting is a central growth strategy for most firms and managers with international experience are instrumental for export decisions. We suggest that such managers can be hired from Multinational Corporations (MNCs). We integrate theory from strategic human capital research into models explaining export decisions. We theorize that hiring managers from MNCs increases the odds of domestic firms to

Hudlymfom är en heterogen grupp av sjukdomar där lymfomcellerna primärt uppträder i huden. T-cellslymfom utgör 70–80 procent och B-cellslymfom 20–30 procent av de primära kutana lymfomen. Mycosis fungoides är det vanligaste hudlymfomet.Den kliniska bilden vid mycosis fungoides kan vara svårtolkad och kan likna vanliga hudsjukdomar som psoriasis och eksem. De histomorfologiska förändringarna vid tiPrimary cutaneous lymphoma is a heterogeneous group of diseases where the malignant lymphocytes are primarily present in the skin at the time of diagnosis. The most common type of primary cutaneous lymphoma is mycosis fungoides. Early stages of mycosis fungoides present with flat or slightly elevated red skin lesions and can resemble eczema or psoriasis. In advanced stages erythrodermia or skin tu

Purpose This paper investigates how the balanced scorecard (BSC) has been translated to fit the public healthcare environment. The paper discusses how the context, consisting of politicians, administrators, and medical professionals has influenced the design and function of the BSC. Design/methodology/approach A qualitative case study approach involving semi-structured interviews were conducted wi

Language and different sexual health discourses constitute barriers to the uptake of information on sexual and reproductive health and rights among migrants. Challenges remain with regards to the design and implementation of culturally appropriate programmes and interventions. This study explored the role of civic communicators in increasing access to sexual health information among migrants reset

The use of participatory action research in media studies is under development and has the last years become notable as a new way of exploring changes that has taken place on the media market the last decades. Media corporations in Sweden continue shutting down local editorial offices and centralize local news reporting to the head editorials. An absence of local reporting in several rural areas i

This special issue contributes to the emerging research field of religion and populism in contemporary media contexts. With a shared focus on how Protestant Nordic contexts align with populist practices in specific ways, the articles provide illustrative examples of how the entanglement between religion, populism and media needs to be taken into account when dealing with contemporary public and po

Importance: Hypochondriasis, also known as health anxiety disorder, is a prevalent, yet underdiagnosed psychiatric disorder characterized by persistent preoccupation about having serious and progressive physical disorders. The risk of mortality among individuals with hypochondriasis is unknown. Objective: To investigate all-cause and cause-specific mortality among a large cohort of individuals wit

In the latter half of the 1360s, Catherine became connected to the mantellate, a group of laywomen, most of whom were financially independent widows like Birgitta. When Tommaso di Antonio da Siena, known in scholarly literature as Caffarini, instigated a hearing in Venice in 1411 as a part of his efforts to see Catherine of Siena canonized, one of his principal strategies for promoting her holines

This article elaborates on the embodiment of heritage via dressing practices in several rural and urban Nordic communities in the United States. Getting dressed is a shared human practice that we engage in and repeat most days, and for special occasions, traditional dress, or folk costume, comes into particular focus. I approach dressing in folk costume as a "situated embodied practice," a mode of

Importance: The nature of the genetic relationship between major depression and bipolar disorder remains unclear and might be clarified by considering disorders outside of the mood spectrum. Objective: To better understand the relationship between genetic liabilities for major depression (MD) and bipolar disorder (BD). Design, Setting, and Participants: A cohort study was conducted with data for i

The term “intracellular complement” has been introduced recently as an umbrella term to distinguish functions of complement proteins that take place intracellularly, rather than in the extracellular environment. However, this rather undefined term leaves some confusion as to the classification of what intracellular complement really is, and as to which intracellular compartment(s) it should refer