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Reconciling Form and Function through Generative Design

The current form-giving activity in industrial design is characterized by explorations that depend on the individual capability to mentally manipulate a solution space from which to select and express the intended result. Industrial designers frequently rely on artistic experimentation, aesthetic inspiration, or design briefs. These points of departure often result in satisfactory results, but the

Dosimetric effects of removing the flattening filter in radiotherapy treatment units

The aim of this work was to investigate the dosimetric effects of removing the flattening filter from conventional C-arm medical linear accelerators. In conventional linear accelerators used for radiotherapy, a flattening filter is positioned in the beam line to provide a uniform lateral dose profile at a specified depth in water. However, for some radiotherapy treatments, a uniform lateral dose p

Negotiating Asylum. The EU acquis, Extraterritorial Protection and the Common Market of Deflection

How are access to asylum and other forms of extraterritorial protection regulated in the European Union? Is the EU acquis in these areas in conformity with international law? What tools does international law offer to solve conflicts between them? And, finally, is law capable of bridging the foundational oppositions embedded in migration and asylum issues? This work combines the potential of legal

Volumetric MRI measurements of velocity and flow - Accuracy, visualisation and technical improvements

In the last two decades, phase-contrast magnetic resonance imaging (PC-MRI) has evolved from two-dimensional velocity and flow measurements to volumetric, time-resolved depictions of velocity fields (4D PC). The acquisition of time-resolved velocity fields allows flow visualisations that might provide better understanding of the dynamics of the cardiac system. Because 4D PC is increasingly being u

The Polyamine Dependence of Cell Cycle Progression-Application in Breast Cancer Treatment

In the normal functioning organism, there is a balance between cell proliferation, cell differentiation, and cell death. An imbalance in these processes results in different diseases. This thesis concerns the imbalance where there is too little cell death and cell differentiation with increased cell proliferation. The result is uncontrolled cell proliferation resulting in the development of cancer

Implementation of MRI gel dosimetry in radiation therapy

Gel dosimetry was used together with magnetic resonance imaging (MRI) to measure three-dimensional absorbed dose distributions in radiation therapy. Two different dosimeters were studied: ferrous- and monomer gel, based on the principles of radiation-induced oxidation and polymerisation, respectively. Single clinical electron and photon beams were evaluated and gel dose distributions were mainly w

Pervaporative aroma recovery during beverage processing

In this study, the fundamental mass and heat transfer properties of the membrane separation process called pervaporation were investigated. The suitability of pervaporation for aroma compound recovery was especially evaluated. The mass transfer in pervaporation is affected by an external mass transfer resistance in the liquid feed boundary layer, i.e. the concentration polarization phenomenon. Th

Biomarkers of aromatic isocyanates in exposed workers

The aromatic isocyanates, toluene diisocyanate (TDI) and methylenediphenyl diisocyanate (MDI), are used in the production of polyurethane (PUR) foams, paints, elastomers and glues. The use of isocyanates is increasing, and exposure to isocyanates is the most common cause of occupational asthma. Biomarkers of TDI and MDI were determined as the corresponding amines, toluenediamine (TDA) and methyle

The (γ,p) reaction in 16O and 18O at Eγ=50 - 70 MeV

A measurement of the reactions 16O(γ,p)15N and 18O(γ,p)17N have been made with tagged photons in the energy range Eγ ≈ 50 – 70 MeV. The protons have been detected in ΔE-E telescopes with silicon strip detectors as ΔE detectors and HPGe crystals as E detectors. Two telescopes have been used with an average angle towards the photon beam of 70 and 110 degrees. The silicon strip detectors have been us

Throughput Analysis of Interfering Packet Radio Networks

In this thesis, a probabilistic framework is presented and used for analysis of the throughput of interfering packet-based radio networks, referred to as packet radio networks (PRNs). Previous research on the performance of PRNs covers a wide variety of systems and aspects in varying levels of detail. However, the work presented in the literature has mostly been limited to fixed packet lengths. Th

Aerosol Measurements as Applied for Exposure Characterization

It is important to decrease the burden of disease. This is in part achieved by decreasing risks. The aim of this thesis is to provide a methodology for the characterization of aerosol exposure, which may lead to negative health effects. Gases and airborne particles may cause negative health effects and the respiratory system is exceptional sensitive. Isocyanate is one group of substances that are

Voice Imitation : A Phonetic Study of Perceptual Illusions and Acoustic Success

This thesis is about voice imitations, more specifically impersonation. Questions are raised about the uniqueness of a person’s voice and speech behaviour and if it is possible to get close to another speaker’s voice and speech. Four main research questions are investigated in different studies. The studies focus mainly on how close the imitation is to the target speaker, and addresses to a lesser

Optimisation and modelling of aroma recovery by pervaporation

During production of concentrated fruit juices, both physical and chemical losses of aroma compounds occur due to heat treatment such as pasteurisation and evaporation. This leads to an inferior quality of the final product. By recovering the aroma complex from fresh juice and then adding it back to the processed juice, heat treatment can be avoided. Hydrophobic pervaporation is an emerging membr

Study of Two-Photon processes at low Q2 using the VSAT calorimeter in the DELPHI experiment

The study is based on data collected at the LEP II accelerator during the second period of the Large Electron-Positron collider operations (1996-2000). During that time the DELPHI (DEtector with Lepton, Photon and Hadron Identification) experiment collected about 90 Gb of data on tape corresponding to 687-691 pb-1 of luminosity. The data obtained by the VSAT (Very Small Angle Tagger) e

Bicyclic Ligands and Catalysts in Asymmetric Synthesis

Synthesis of compounds based on the structurally rigid bicyclo[2.2.2]octane and the dibenzobicyclo[3.3.1]nonane frameworks and also their application as ligands and catalysts in asymmetric synthesis are described. For the synthesis of 1,3-diols based on the bicyclo[2.2.2]octane framework, an improved synthesis of the starting material bicyclo[2.2.2]octan-2,6-dione was developed and performed at 0

Att utmana förändringens gränser : En studie om förändringsarbete, partnerskap och kön med Equal-programmet som exempel

In this thesis the overall aim is to analyse conceptions of change with the point of departure being texts developed within the framework of three development partnerships financed by the European Social Fund's Equal Programme 2001-2007. The development partnerships, consisting of collaborating parties from both the public and private sector, aimed at developing new methods and ideas in order to c

Två demokratier – två system: Grundlagsändring i Sverige och Danmark

One of the most invasive choices a democratic society can make is to amend its constitution. Despite the fact that Sweden and Denmark are frequently described as having very similar democracies, the two nations have made different decisions about how these changes should be carried out. The purpose of this essay is to compare and contrast Sweden's and Denmark's constitutional amendment pro

Säkerhetsillusion? En studie i organisationskultur och intern informationssäkerhet på ett svensk säkerhetsföretag

In the era of privatization and securitization, private security companies are becoming a more important actor for ensuring safety in a society felt increasingly unsafe. Ensuring safety has been seen as a fundamental task of the state, which is now transferring to the private sector. This study examines one of Sweden's private security companies. Do they consider themselves as having a social