Filtyp
Graves' disease (GD) is a complex autoimmune disorder characterized by hyperthyroidism and diffuse goitre. 25-50% of the patients with GD develop eye symptoms, Graves' ophthalmopathy (GO). The overall aim of this thesis was to explore the molecular etiology of GD and GO. By studying gene expression in Studies I, III, and IV, we demonstrated that adipocyte-related immediate early genes (IEGs) incl
The atmospheric concentration of elemental carbon (EC) in Europe during the six-year period 2005-2010 has been simulated with the EMEP MSC-W model. The model bias compared to EC measurements was less than 20% for most of the examined sites. The model results suggest that fossil fuel combustion is the dominant source of EC in most of Europe but that there are important contributions also from resid
Citizenship education is a popular and contested phenomenon in liberal democratic societies. It is difficult to imagine a school system that does not contribute to the preservation and improvement of society through education of democratic, responsible and tolerant citizens. On the contrary, the execution of such education is full of caveats, controversy and resistance. This special issue examines
Experimental studies have suggested that autoimmunity is involved in atherosclerosis and provided evidence that both protective and pro-atherogenic immune responses exist. This concept has received support from small clinical studies implicating autoantibodies directed against apolipoprotein B-100 (apoB-100) in human atherosclerosis. We examined circulating autoantibodies directed against native a
The Cambrian–Ordovician boundary interval in Scandinavia is characterized by largely endemic trilobite species and fossil-meager intervals within the Alum Shale Formation. Previous investigations of this interval in Scandinavia, based on drill cores, are rather sketchy. In order to characterize the faunal signature in a largely dysoxic setting during this time interval, as well as providing biostr
CONTEXT: Prior studies have demonstrated conflicting results regarding how much information novel biomarkers add to cardiovascular risk assessment. OBJECTIVE: To evaluate the utility of contemporary biomarkers for predicting cardiovascular risk when added to conventional risk factors. DESIGN, SETTING, AND PARTICIPANTS: Cohort study of 5067 participants (mean age, 58 years; 60% women) without cardi
Zabrze is a medium size town of 200 000 inhabitants in the region of Upper Silesia, Poland. The development of the town was originally based on the exploitation of heavy industries. In the past few years Zabrze has, however, moved towards more service and tourism oriented industries. As part of this journey, the city of Zabrze sees the need to improve its existing waste management system. This rep
It is well known that nature offers an abundance of materials and processes that can be adapted in low-tech fashion, to fabricate systems capable of removing pollutants from wastewater. During the last decade, extensive basic and engineering research on such natural treatment systems have led to improvement of the quality of discharged wastewaters. However, the mechanisms of natural treatment and
The family with the elderly and the home help workers’ team constitute two organisations, which meet in the care work. In this context the family is extended and often constitute not only members from the nuclear family but also other members of the network of relatives, whom take part in the care of the elderly. The extended family may in some cases include four generations (Finch & Mason, 19
Abstract The thesis aims at providing a better understanding of public policy instruments used in policy-making within the energy sector, particularly regarding their role in the change towards an increased use of renewable energy sources for generation of electricity. The research was guided by an underlying assumption that a markedly higher proportion of the energy generated from renewable sour
