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Prediabetes is a state of glycaemic dysregulation below the diagnostic threshold of type 2 diabetes (T2D). Globally, ~352 million people have prediabetes, of which 35–50% develop full-blown diabetes within five years. T2D and its complications are costly to treat, causing considerable morbidity and early mortality. Whether prediabetes is causally related to diabetes complications is unclear. Here
Dataharmonisering är en förutsättning för smarta städer, för ett mer effektivt informationsflöde i samhällsbyggnadsprocessen och för många andra tillämpningar i en stadsmiljö. Vid ett bästa tänkbart scenario kommer dataharmonisering att resultera i ett digitalt informationsflöde som inkluderar information från ett objekts hela livscykel, till exempel för byggnader, vägar och tunnlar. Alla aktörer Data harmonisation is a prerequisite for smart cities, for a more efficient information flow in the planning and building process and for many applications in the urban environment. Ideally, data harmonisation will result in a digital information flow that include information from the whole lifecycle of a feature, for example for buildings, roads and tunnels. All actors and applications involved i
Vi vill med den här artikeln peka på att Sveriges städer har flera utmaningar kring styrning och hantering av vatten, samt föreslår sju principer för lösningar. Klimatförändringarna och den urbana tillväxten gör att åtgärder behövs nu för att hantera både vattenbrist och översvämning på ett integrerat sätt. Här fokuserar vi på kommunnivå och urbana områden, där vi argumenterar för att det behövs e
During the last decade the link between religion and right-wing populism has been underlined by scholars, viewing the latter as a form of ‘religious backlash’ and encouraging progressives to fight back. However, by setting the religious against the secular, these arguments, paradoxically, have contributed to the development of populism—by enforcing what Ryszard Bobrowicz and Johanna Gustafsson Lun
The transport of neutrons in long beamlines at spallation neutron sources presents a unique challenge for Monte-Carlo transport calculations. This is due to the need to accurately model the deep-penetration of high-energy neutrons through meters of thick dense shields close to the source and at the same time to model the transport of low- energy neutrons across distances up to around 150 m in leng
Fine-tuning of insulin release from pancreatic β-cells is essential to maintain blood glucose homeostasis. Here, we report that insulin secretion is regulated by a circular RNA containing the lariat sequence of the second intron of the insulin gene. Silencing of this intronic circular RNA in pancreatic islets leads to a decrease in the expression of key components of the secretory machinery of β-c
BACKGROUND AND OBJECTIVES: Dementia cases are expected to triple during the next 30 years, highlighting the importance of finding modifiable risk factors for dementia. The aim of this study is to investigate whether adherence to conventional dietary recommendations or to a modified Mediterranean diet are associated with subsequent lower risk of developing all-cause dementia, Alzheimer's disease (A
Recent socioeconomic changes have created and intensified paradoxical organizational tensions that companies in numerous industries, including the construction sector, need to address when organizing and managing their activities. The nature of these tensions has not been sufficiently explored in the existing construction management literature. Thus, this study analyzes tensions between control an
Temporariness of refugee protection has started to emerge as a new standard in the policies of European countries. Given this development, the article focuses on one specific issue related to this temporariness: how refugee status intertwines with the conditions for the granting, revocation and prolongation of national residence permits. What are the interconnections between refugee status, includ
Top civil society organisations (CSOs) face a particular legitimacy dilemma as they need to have leaders who are seen as legitimate by the elite groups they interact with, and by those they represent. This article investigates how they handle this dilemma by studying legitimation practices of newly appointed leaders. Based on Weber’s theory of authority and Pitkin’s theory of representation, the a
ype 2 diabetes (T2D) and obesity are multifactorial and polygenic metabolic diseases. Combinations of genetic and non-genetic risk factors such as risk SNPs, age, unhealthy diets, and physical inactivity increase the risk for these diseases. Emerging data also support a key role for epigenetic mechanisms in the pathogenesis of T2D and obesity. In this chapter, we summarize current knowledge of epi
Målbeskrivningen för den nya sexåriga läkarutbildningen lyfter fram att en läkare ska kunna visa förmåga att självständigt inleda diagnostik och behandling vid livshotande akuta tillstånd. Sedan 2017 har fler än tusen läkarstudenter i Lund genomgått 5 veckors utbildning i akut omhändertagande.Under utbildningen handlägger studenterna ett stort antal olika livshotande akuta tillstånd i fullskalesim
